44 articles for thisTarget
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Article Title
Organization
Synthesis and quantitative structure-activity relationships of diclofenac analogues.
Ciba-Geigy
New alpha-thiol dipeptide dual inhibitors of angiotensin-I converting enzyme and neutral endopeptidase EC 3.4.24.11.
Ciba-Geigy
N-Phosphonomethyl dipeptides and their phosphonate prodrugs, a new generation of neutral endopeptidase (NEP, EC 3.4.24.11) inhibitors.
Ciba-Geigy
Design and synthesis of an orally active macrocyclic neutral endopeptidase 24.11 inhibitor.
Ciba-Geigy
4-Amidinoindan-1-one 2'-amidinohydrazone: a new potent and selective inhibitor of S-Adenosylmethionine decarboxylase.
Ciba-Geigy
Thromboxane receptor antagonism combined with thromboxane synthase inhibition. 2. Synthesis and biological activity of 8-(benzenesulfonamido)-7-(3-pyridinyl)octaonic acid and related compounds.
Ciba-Geigy
Definition and display of steric, hydrophobic, and hydrogen-bonding properties of ligand binding sites in proteins using Lee and Richards accessible surface: validation of a high-resolution graphical tool for drug design.
Ciba-Geigy
Highly selective adenosine A2 receptor agonists in a series of N-alkylated 2-aminoadenosines.
Ciba-Geigy
Sulfonylbenzoyl-nitrostyrenes: potential bisubstrate type inhibitors of the EGF-receptor tyrosine protein kinase.
Ciba-Geigy
Fadrozole hydrochloride: a potent, selective, nonsteroidal inhibitor of aromatase for the treatment of estrogen-dependent disease.
Ciba-Geigy
2-(Arylalkylamino)adenosin-5'-uronamides: a new class of highly selective adenosine A2 receptor ligands.
Ciba-Geigy
Benzofuro[2,3-c]pyridin-6-ols: synthesis, affinity for opioid-receptor subtypes, and antinociceptive activity.
Ciba-Geigy
Synthesis, opioid receptor binding profile, and antinociceptive activity of 1-azaspiro[4.5]decan-10-yl amides.
Ciba-Geigy
New aza-dipeptide analogues as potent and orally absorbed HIV-1 protease inhibitors: candidates for clinical development.
Ciba-Geigy
Meta-substituted benzofused macrocyclic lactams as zinc metalloprotease inhibitors.
Ciba-Geigy
Aromatase inhibitors: synthesis, biological activity, and binding mode of azole-type compounds.
Ciba-Geigy
Thromboxane receptor antagonism combined with thromboxane synthase inhibition. 5. Synthesis and evaluation of enantiomers of 8-[[(4-chlorophenyl)sulfonyl]amino]-4-(3-pyridinylalkyl)octanoic acid.
Ciba-Geigy
S-adenosylmethionine decarboxylase inhibitors: new aryl and heteroaryl analogues of methylglyoxal bis(guanylhydrazone).
Ciba-Geigy
Heterocyclic lactam derivatives as dual angiotensin converting enzyme and neutral endopeptidase 24.11 inhibitors.
Ciba-Geigy
Structure-based design of inhibitors of purine nucleoside phosphorylase. 4. A study of phosphate mimics.
Ciba-Geigy
Dianilinophthalimides: potent and selective, ATP-competitive inhibitors of the EGF-receptor protein tyrosine kinase.
Ciba-Geigy
Derivatives of 2-[[N-(Aminocarbonyl)-N-hydroxyamino]methyl]-1,4- benzodioxan as orally active 5-lipoxygenase inhibitors.
Ciba-Geigy
Phosphinic acid analogues of GABA. 2. Selective, orally active GABAB antagonists.
Ciba-Geigy
Phosphinic acid analogues of GABA. 1. New potent and selective GABAB agonists.
Ciba-Geigy
Inhibition of peptidylglycine alpha-amidating monooxygenase by N-substituted homocysteine analogs.
Ciba-Geigy
Structure-activity profile of a series of novel triazoloquinazoline adenosine antagonists.
Ciba-Geigy
Synthesis and biological activity of some transition-state inhibitors of human renin.
Ciba-Geigy
2H-[1]benzopyrano[3,4-b]pyridines: synthesis and activity at central monoamine receptors.
Ciba-Geigy
Synthesis and aromatase inhibitory activity of novel 1-(4-aminophenyl)-3-azabicyclo[3.1.0]hexane- and -[3.1.1]heptane-2,4- diones.
Ciba-Geigy
Nonpeptidic angiotensin II antagonists: synthesis and in vitro activity of a series of novel naphthalene and tetrahydronaphthalene derivatives.
Ciba-Geigy
Thromboxane receptor antagonism combined with thromboxane synthase inhibition. 1. (+/-)-(3-pyridinylbicycloheptyl)alkanoic acids.
Ciba-Geigy
2-substituted 3-(aminooxy)propanamines as inhibitors of ornithine decarboxylase: synthesis and biological activity.
Ciba-Geigy
Thromboxane receptor antagonism combined with thromboxane synthase inhibition. 4. 8-[[(4-Chlorophenyl)sulfonyl]amino]-4-(3-(3-pyridinyl) propyl)octanoic acid and analogs.
Ciba-Geigy
Thromboxane receptor antagonism combined with thromboxane synthase inhibition. 3. Pyridinylalkyl-substituted 8-[(arylsulfonyl)amino]octanoic acids.
Ciba-Geigy
3-(1H-pyrrolo[2,3-B]pyridin-2-yl)-1H-pyrazolo[3,4-B] pyridines and therapeutic uses thereof
Samumed
Synthesis and structure-activity relationship of imidazo(1,2-a)thieno(3,2-e)pyrazines as IKK-beta inhibitors.
Bristol-Myers Squibb