Compile Data Set for Download or QSAR
Report error Found 46 Enz. Inhib. hit(s) with all data for entry = 50036385
TargetNeprilysin(Rat)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50048318((S)-2-{[1-((S)-2-Mercapto-3-methyl-butyrylamino)-c...)
Affinity DataIC50: 1.20nMAssay Description:Evaluation of in vitro inhibitory activity against Neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetNeprilysin(Rat)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50048320((S)-2-{[1-((S)-2-Mercapto-3-methyl-butyrylamino)-c...)
Affinity DataIC50: 1.5nMAssay Description:Evaluation of in vitro inhibitory activity against Neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetNeprilysin(Rat)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50048312((S)-3-(4-Hydroxy-phenyl)-2-{[1-((S)-2-mercapto-3-m...)
Affinity DataIC50: 1.5nMAssay Description:Evaluation of in vitro inhibitory activity against Neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetNeprilysin(Rat)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50048304((S)-3-(4-Fluoro-phenyl)-2-{[1-((S)-2-mercapto-3-me...)
Affinity DataIC50: 1.80nMAssay Description:Evaluation of in vitro inhibitory activity against Neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetNeprilysin(Rat)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50048303((S)-3-(5-Hydroxy-1H-indol-3-yl)-2-{[1-((S)-2-merca...)
Affinity DataIC50: 2nMAssay Description:Evaluation of in vitro inhibitory activity against Neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetNeprilysin(Rat)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50048314((S)-3-(1H-Indol-3-yl)-2-{[1-((S)-2-mercapto-3-meth...)
Affinity DataIC50: 2.10nMAssay Description:Evaluation of in vitro inhibitory activity against Neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetNeprilysin(Rat)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50048315((S)-2-{[1-((S)-2-Mercapto-3-methyl-butyrylamino)-c...)
Affinity DataIC50: 2.20nMAssay Description:Evaluation of in vitro inhibitory activity against Neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetNeprilysin(Rat)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50048305((S)-2-{[1-((S)-2-Mercapto-3-methyl-butyrylamino)-c...)
Affinity DataIC50: 2.60nMAssay Description:Evaluation of in vitro inhibitory activity against Neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetNeprilysin(Rat)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50048310((S)-2-{[1-((S)-2-Mercapto-3-methyl-butyrylamino)-c...)
Affinity DataIC50: 3nMAssay Description:Evaluation of in vitro inhibitory activity against Neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetNeprilysin(Rat)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50048317((S)-3-(4-Hydroxy-phenyl)-2-{[1-((S)-2-mercapto-3-p...)
Affinity DataIC50: 3nMAssay Description:Evaluation of in vitro inhibitory activity against Neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetNeprilysin(Rat)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50048316((S)-2-{[1-((S)-2-Mercapto-3-methyl-butyrylamino)-c...)
Affinity DataIC50: 3.10nMAssay Description:Evaluation of in vitro inhibitory activity against Neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetNeprilysin(Rat)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50048308((S)-3-(4-Hydroxy-phenyl)-2-{[1-((S)-2-mercapto-3-m...)
Affinity DataIC50: 5nMAssay Description:Evaluation of in vitro inhibitory activity against Neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetNeprilysin(Rat)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50048311((S)-3-(4-Hydroxy-phenyl)-2-({1-[(1-mercapto-cyclop...)
Affinity DataIC50: 5.20nMAssay Description:Evaluation of in vitro inhibitory activity against Neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetNeprilysin(Rat)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM21641(2-(2-benzyl-3-sulfanylpropanamido)acetic acid | CH...)
Affinity DataIC50: 5.40nMAssay Description:Evaluation of in vitro inhibitory activity against Neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNeprilysin(Rat)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50048322((S)-3-(4-Hydroxy-phenyl)-2-{[4-((S)-2-mercapto-3-m...)
Affinity DataIC50: 6.40nMAssay Description:Evaluation of in vitro inhibitory activity against Neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Rabbit)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50048312((S)-3-(4-Hydroxy-phenyl)-2-{[1-((S)-2-mercapto-3-m...)
Affinity DataIC50: 7nMAssay Description:Evaluation of in vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetNeprilysin(Rat)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50048313((S)-3-(4-Hydroxy-phenyl)-2-{[1-((S)-2-mercapto-3-m...)
Affinity DataIC50: 8.70nMAssay Description:Evaluation of in vitro inhibitory activity against Neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Rabbit)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50367254(ENALAPRILAT)
Affinity DataIC50: 8.80nMAssay Description:Evaluation of in vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetNeprilysin(Rat)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50048324((S)-3-(4-Hydroxy-phenyl)-2-[2-((S)-2-mercapto-3-me...)
Affinity DataIC50: 9.20nMAssay Description:Evaluation of in vitro inhibitory activity against Neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Rabbit)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM21642((2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolid...)
Affinity DataIC50: 10nMAssay Description:Evaluation of in vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Rabbit)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50048314((S)-3-(1H-Indol-3-yl)-2-{[1-((S)-2-mercapto-3-meth...)
Affinity DataIC50: 10nMAssay Description:Evaluation of in vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Rabbit)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50048322((S)-3-(4-Hydroxy-phenyl)-2-{[4-((S)-2-mercapto-3-m...)
Affinity DataIC50: 11nMAssay Description:Evaluation of in vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Rabbit)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50048305((S)-2-{[1-((S)-2-Mercapto-3-methyl-butyrylamino)-c...)
Affinity DataIC50: 11nMAssay Description:Evaluation of in vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Rabbit)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50048303((S)-3-(5-Hydroxy-1H-indol-3-yl)-2-{[1-((S)-2-merca...)
Affinity DataIC50: 13nMAssay Description:Evaluation of in vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetNeprilysin(Rat)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50048323((S)-3-(4-Hydroxy-phenyl)-2-{[2-((S)-2-mercapto-3-m...)
Affinity DataIC50: 15nMAssay Description:Evaluation of in vitro inhibitory activity against Neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Rabbit)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50048324((S)-3-(4-Hydroxy-phenyl)-2-[2-((S)-2-mercapto-3-me...)
Affinity DataIC50: 15nMAssay Description:Evaluation of in vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetNeprilysin(Rat)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50048309((S)-3-(4-Hydroxy-phenyl)-2-{[1-(2-mercapto-acetyla...)
Affinity DataIC50: 15nMAssay Description:Evaluation of in vitro inhibitory activity against Neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Rabbit)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50048308((S)-3-(4-Hydroxy-phenyl)-2-{[1-((S)-2-mercapto-3-m...)
Affinity DataIC50: 15nMAssay Description:Evaluation of in vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetNeprilysin(Rat)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50048319((S)-3-Biphenyl-4-yl-2-{[1-((S)-2-mercapto-3-methyl...)
Affinity DataIC50: 16nMAssay Description:Evaluation of in vitro inhibitory activity against Neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Rabbit)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50048311((S)-3-(4-Hydroxy-phenyl)-2-({1-[(1-mercapto-cyclop...)
Affinity DataIC50: 17nMAssay Description:Evaluation of in vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Rabbit)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50048320((S)-2-{[1-((S)-2-Mercapto-3-methyl-butyrylamino)-c...)
Affinity DataIC50: 18nMAssay Description:Evaluation of in vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Rabbit)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50048315((S)-2-{[1-((S)-2-Mercapto-3-methyl-butyrylamino)-c...)
Affinity DataIC50: 19nMAssay Description:Evaluation of in vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Rabbit)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50048317((S)-3-(4-Hydroxy-phenyl)-2-{[1-((S)-2-mercapto-3-p...)
Affinity DataIC50: 22nMAssay Description:Evaluation of in vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Rabbit)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50048304((S)-3-(4-Fluoro-phenyl)-2-{[1-((S)-2-mercapto-3-me...)
Affinity DataIC50: 24nMAssay Description:Evaluation of in vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetNeprilysin(Rat)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50048307((S)-3-(4-Hydroxy-phenyl)-2-{[2-((S)-2-mercapto-3-m...)
Affinity DataIC50: 25nMAssay Description:Evaluation of in vitro inhibitory activity against Neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Rabbit)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50048307((S)-3-(4-Hydroxy-phenyl)-2-{[2-((S)-2-mercapto-3-m...)
Affinity DataIC50: 26nMAssay Description:Evaluation of in vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetNeprilysin(Rat)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50251742((S)-2-{(R)-2-[Hydroxy-((2R,3R,4R,5R,6S)-3,4,5-trih...)
Affinity DataIC50: 26nMAssay Description:Evaluation of in vitro inhibitory activity against Neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetNeprilysin(Rat)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50048306((S)-2-[(S)-3-Biphenyl-4-yl-2-((S)-2-mercapto-3-met...)
Affinity DataIC50: 28nMAssay Description:Evaluation of in vitro inhibitory activity against Neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Rabbit)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50048318((S)-2-{[1-((S)-2-Mercapto-3-methyl-butyrylamino)-c...)
Affinity DataIC50: 30nMAssay Description:Evaluation of in vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Rabbit)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50048313((S)-3-(4-Hydroxy-phenyl)-2-{[1-((S)-2-mercapto-3-m...)
Affinity DataIC50: 33nMAssay Description:Evaluation of in vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Rabbit)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50048310((S)-2-{[1-((S)-2-Mercapto-3-methyl-butyrylamino)-c...)
Affinity DataIC50: 35nMAssay Description:Evaluation of in vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Rabbit)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50048316((S)-2-{[1-((S)-2-Mercapto-3-methyl-butyrylamino)-c...)
Affinity DataIC50: 37nMAssay Description:Evaluation of in vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Rabbit)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50048309((S)-3-(4-Hydroxy-phenyl)-2-{[1-(2-mercapto-acetyla...)
Affinity DataIC50: 58nMAssay Description:Evaluation of in vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Rabbit)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50048306((S)-2-[(S)-3-Biphenyl-4-yl-2-((S)-2-mercapto-3-met...)
Affinity DataIC50: 62nMAssay Description:Evaluation of in vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Rabbit)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50048323((S)-3-(4-Hydroxy-phenyl)-2-{[2-((S)-2-mercapto-3-m...)
Affinity DataIC50: 65nMAssay Description:Evaluation of in vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Rabbit)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50048319((S)-3-Biphenyl-4-yl-2-{[1-((S)-2-mercapto-3-methyl...)
Affinity DataIC50: 139nMAssay Description:Evaluation of in vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed