Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50035934
TargetAromatase(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM8611(CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...)
Affinity DataIC50: 0.0300nMAssay Description:In vitro inhibition of estrogen production in hamster ovarian tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50368174(CHEMBL1203762)
Affinity DataIC50: 2nMAssay Description:In vitro inhibition of cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM8611(CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...)
Affinity DataIC50: 6.40nMAssay Description:In vitro inhibition of cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50368173(CHEMBL1203766)
Affinity DataIC50: 7.60nMAssay Description:In vitro inhibition of cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50008725(CHEMBL162834 | 4-(6,7,8,9-Tetrahydro-5H-imidazo[1,...)
Affinity DataIC50: 14nMAssay Description:In vitro inhibition of cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50008726(CHEMBL348913 | [4-(5,6,7,8-Tetrahydro-imidazo[1,5-...)
Affinity DataIC50: 14nMAssay Description:In vitro inhibition of cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50008729(1-(4-Cyanobenzyl)-5-methyl-1H-imidazole | CHEMBL16...)
Affinity DataIC50: 15nMAssay Description:In vitro inhibition of cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50008733(4-((1H-imidazol-1-yl)methyl)benzonitrile | 4-Imida...)
Affinity DataIC50: 15nMAssay Description:In vitro inhibition of cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50368172(CHEMBL1203757)
Affinity DataIC50: 18nMAssay Description:In vitro inhibition of cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50368175(CHEMBL1203760)
Affinity DataIC50: 21nMAssay Description:In vitro inhibition of cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM8611(CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...)
Affinity DataIC50: 39nMAssay Description:In vitro inhibition of cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM8611(CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...)
Affinity DataIC50: 39nMAssay Description:In vitro inhibition of cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50008724(CHEMBL163420 | 4-(5,6,7,8-Tetrahydro-imidazo[1,5-a...)
Affinity DataIC50: 93nMAssay Description:In vitro inhibition of cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50008730(CHEMBL163413 | 4-(5,6,7,8-Tetrahydro-imidazo[1,5-a...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Rat)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM8611(CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ACTH-stimulated aldosterone production in rat adrenal tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | C...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human placental microsome cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | C...)
Affinity DataIC50: 3.00E+4nMAssay Description:In vitro inhibition of estrogen production in hamster ovarian tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | C...)
Affinity DataIC50: 8.00E+4nMAssay Description:In vitro inhibition of progesterone production in hamster ovarian tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Rat)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM8611(CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of ACTH-stimulated corticosterone production in rat adrenal tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM10044((2S,15S)-15-methyl-2-[(methylsulfanyl)methyl]tetra...)
Affinity DataKi:  1nMAssay Description:Aromatase inhibitor potency as iron-binding-related type II difference spectrumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM8611(CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...)
Affinity DataKi:  1.5nMAssay Description:Aromatase inhibitor potency as iron-binding-related type II difference spectrumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | C...)
Affinity DataKi:  470nMAssay Description:Competitive inhibition of human placental Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed