BDBM648427 US20240033256, Compound 2

SMILES CCN1CC(O)c2c(C1)c1cc(OC)c(OC)cc1c1cc(OC)ccc21

InChI Key InChIKey=YDGQYKBAQLQULF-UHFFFAOYSA-N

Data  9 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 648427   

TargetReplicase polyprotein 1ab(2019-nCoV)
National Health Research Institutes

US Patent
LigandPNGBDBM648427(US20240033256, Compound 2)
Affinity DataEC50:  9.10nMAssay Description:Vero E6 cells derived from BCRC #60476 (Bioresource Collection and Research Center, Hsinchu, Taiwan) were treated with each compound at an indicated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
National Health Research Institutes

US Patent
LigandPNGBDBM648427(US20240033256, Compound 2)
Affinity DataEC50:  13.9nMAssay Description:Vero E6 cells derived from BCRC #60476 (Bioresource Collection and Research Center, Hsinchu, Taiwan) were treated with each compound at an indicated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
National Health Research Institutes

US Patent
LigandPNGBDBM648427(US20240033256, Compound 2)
Affinity DataEC50:  10.8nMAssay Description:The assay was performed in triplicate in 24-well tissue culture plates. Vero E6 cells were seeded in Dulbecco's modified Eagle's medium ( DME...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
National Health Research Institutes

US Patent
LigandPNGBDBM648427(US20240033256, Compound 2)
Affinity DataEC50:  13.8nMAssay Description:The assay was performed in triplicate in 24-well tissue culture plates. Vero E6 cells were seeded in Dulbecco's modified Eagle's medium ( DME...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetReplicase polyprotein 1ab(HCoV-OC43)
National Health Research Institutes

US Patent
LigandPNGBDBM648427(US20240033256, Compound 2)
Affinity DataEC50:  16.4nMAssay Description:Human colon adenocarcinoma cell line HCT-8 (ATCC@ CCL-244, American Type Culture Collection, Manassas, VA, USA) was obtained from American Type Cultu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetReplicase polyprotein 1ab(HCoV-229E)
National Health Research Institutes

US Patent
LigandPNGBDBM648427(US20240033256, Compound 2)
Affinity DataEC50:  6.5nMAssay Description:HCoV-229E viral genome replication was examined by RT-PCR with specific primers against its open reading frame 1 (“ORF1”) and ORF nucleocap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetGenome polyprotein(ZIKV)
National Health Research Institutes

US Patent
LigandPNGBDBM648427(US20240033256, Compound 2)
Affinity DataEC50:  15.3nMAssay Description:Vero E6 cells (BCRC #60476, Bioresource Collection and Research Center, Hsinchu, Taiwan) were treated with one of Compounds 1-9 at a predetermined co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetGenome polyprotein(DENV-1)
National Health Research Institutes

US Patent
LigandPNGBDBM648427(US20240033256, Compound 2)
Affinity DataEC50:  4.30nMAssay Description:Vero E6 cells (BCRC #60476, Bioresource Collection and Research Center, Hsinchu, Taiwan) were treated with one of Compounds 1-9 at a predetermined co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetGenome polyprotein(DENV-2)
National Health Research Institutes

US Patent
LigandPNGBDBM648427(US20240033256, Compound 2)
Affinity DataEC50:  4.70nMAssay Description:Vero E6 cells (BCRC #60476, Bioresource Collection and Research Center, Hsinchu, Taiwan) were treated with one of Compounds 1-9 at a predetermined co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent