28 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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Article Title
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Synthesis and biological evaluation of a unique heparin mimetic hexasaccharide for structure-activity relationship studies.
Momenta Pharmaceuticals
Hit identification of novel heparanase inhibitors by structure- and ligand-based approaches.
Centro De Investigaci�N Pr�Ncipe Felipe
QSAR study of heparanase inhibitors activity using artificial neural networks and Levenberg-Marquardt algorithm.
Sharif University of Technology
Discovery of PG545: a highly potent and simultaneous inhibitor of angiogenesis, tumor growth, and metastasis.
Progen Pharmaceuticals
Synthesis and biological evaluation of polysulfated oligosaccharide glycosides as inhibitors of angiogenesis and tumor growth.
Progen Pharmaceuticals
Synthesis and heparanase inhibitory activity of sulfated mannooligosaccharides related to the antiangiogenic agent PI-88.
Progen Pharmaceuticals
Design Principle of Heparanase Inhibitors: A Combined In Vitro and In Silico Study.
University of Florida
Discovery of a novel tetrahydroimidazo[1,2-a]pyridine-5-carboxylic acid derivative as a potent and selective heparanase-1 inhibitor utilizing an improved synthetic approach.
Taisho Pharmaceutical Co, Ltd
Amphiphilic Heparinoids as Potent Antiviral Agents against SARS-CoV-2.
University of Queensland
Structure-based lead optimization to improve potency and selectivity of a novel tetrahydroimidazo[1,2-a]pyridine-5-carboxylic acid series of heparanase-1 inhibitor.
Taisho Pharmaceutical
Discovery and development of small-molecule heparanase inhibitors.
University of Florida
Amphiphilic glycoconjugates as potential anti-cancer chemotherapeutics.
Emory University
Recent advances in the discovery of heparanase inhibitors as anti-cancer agents.
Shandong University
The SAR and action mechanisms of autophagy inhibitors that eliminate drug resistance.
Guangzhou University of Chinese Medicine
Antitumor activity and structure-activity relationship of heparanase inhibitors: Recent advances.
Guangzhou University of Chinese Medicine
Lead identification of novel tetrahydroimidazo[1,2-a]pyridine-5-carboxylic acid derivative as a potent heparanase-1 inhibitor.
Taisho Pharmaceutical Co.
Synthesis, biological activity, and preliminary pharmacokinetic evaluation of analogues of a phosphosulfomannan angiogenesis inhibitor (PI-88).
Progen Industries
1-[4-(1H-Benzoimidazol-2-yl)-phenyl]-3-[4-(1H-benzoimidazol-2-yl)-phenyl]-urea derivatives as small molecule heparanase inhibitors.
Imclone Systems
N-(4-{[4-(1H-Benzoimidazol-2-yl)-arylamino]-methyl}-phenyl)-benzamide derivatives as small molecule heparanase inhibitors.
Imclone Systems
Furanyl-1,3-thiazol-2-yl and benzoxazol-5-yl acetic acid derivatives: novel classes of heparanase inhibitor.
Celltech R&D
2,3-Dihydro-1,3-dioxo-1H-isoindole-5-carboxylic acid derivatives: a novel class of small molecule heparanase inhibitors.
Celltech R&D
Rational design and synthesis of novel heparan sulfate mimetic compounds as antiadhesive agents.
Riken Discovery Research Institute
Modulating Heparanase Activity: Tuning Sulfation Pattern and Glycosidic Linkage of Oligosaccharides.
Wayne State University
Novel Benzazole Derivatives Endowed with Potent Antiheparanase Activity.
"Sapienza" Universit£
Novel Symmetrical Benzazolyl Derivatives Endowed with Potent Anti-Heparanase Activity.
"Sapienza" Universit£
Synthesis and antitumor activities of 1,2,3-triazines and their benzo- and heterofused derivatives.
University of Palermo
Arylamidonaphtalene sulfonate compounds as a novel class of heparanase inhibitors.
University of Ferrara
