Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50007677
TargetPlatelet factor 4(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50511576(CHEMBL4537045)
Affinity DataKd:  1.60E+4nMAssay Description:Binding affinity to PF4 (unknown origin) by BLI assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50511579(CHEBI:61033 | Fondaparinux)
Affinity DataIC50: 11nMAssay Description:Inhibition of coagulation factor 10a (unknown origin) incubated for 2 mins in presence of AT3 by chromogenic substrate based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHeparanase(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50511576(CHEMBL4537045)
Affinity DataIC50: 393nMAssay Description:Inhibition of heparanase (unknown origin) using biotin-heparan sulfate-Eu cryptate as substrate preincubated for 10 mins followed by substrate additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50511576(CHEMBL4537045)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of coagulation factor 10a (unknown origin) incubated for 2 mins in presence of AT3 by chromogenic substrate based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetProthrombin(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50511576(CHEMBL4537045)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of coagulation factor 2a (unknown origin) incubated for 2 mins in presence of AT3 by chromogenic substrate based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHeparanase(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50511571(CHEMBL4462283)
Affinity DataIC50: 3.01E+3nMAssay Description:Inhibition of heparanase (unknown origin) using biotin-heparan sulfate-Eu cryptate as substrate preincubated for 10 mins followed by substrate additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHeparanase(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50511572(CHEMBL4514370)
Affinity DataIC50: 3.94E+3nMAssay Description:Inhibition of heparanase (unknown origin) using biotin-heparan sulfate-Eu cryptate as substrate preincubated for 10 mins followed by substrate additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHeparanase(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50511582(CHEMBL4469617)
Affinity DataIC50: 8.12E+3nMAssay Description:Inhibition of heparanase (unknown origin) using biotin-heparan sulfate-Eu cryptate as substrate preincubated for 10 mins followed by substrate additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHeparanase(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50511583(CHEMBL4447606)
Affinity DataIC50: 8.23E+3nMAssay Description:Inhibition of heparanase (unknown origin) using biotin-heparan sulfate-Eu cryptate as substrate preincubated for 10 mins followed by substrate additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHeparanase(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50511574(CHEMBL4466579)
Affinity DataIC50: 9.54E+3nMAssay Description:Inhibition of heparanase (unknown origin) using biotin-heparan sulfate-Eu cryptate as substrate preincubated for 10 mins followed by substrate additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHeparanase(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50511584(CHEMBL4438835)
Affinity DataIC50: 9.96E+3nMAssay Description:Inhibition of heparanase (unknown origin) using biotin-heparan sulfate-Eu cryptate as substrate preincubated for 10 mins followed by substrate additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHeparanase(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50511577(CHEMBL4534223)
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibition of heparanase (unknown origin) using biotin-heparan sulfate-Eu cryptate as substrate preincubated for 10 mins followed by substrate additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHeparanase(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50511581(CHEMBL4474626)
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of heparanase (unknown origin) using biotin-heparan sulfate-Eu cryptate as substrate preincubated for 10 mins followed by substrate additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHeparanase(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50511573(CHEMBL4573010)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of heparanase (unknown origin) using biotin-heparan sulfate-Eu cryptate as substrate preincubated for 10 mins followed by substrate additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHeparanase(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50511578(CHEMBL4551276)
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of heparanase (unknown origin) using biotin-heparan sulfate-Eu cryptate as substrate preincubated for 10 mins followed by substrate additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHeparanase(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50511580(CHEMBL4540273)
Affinity DataIC50: 4.17E+4nMAssay Description:Inhibition of heparanase (unknown origin) using biotin-heparan sulfate-Eu cryptate as substrate preincubated for 10 mins followed by substrate additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHeparanase(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50511575(CHEMBL4462552)
Affinity DataIC50: 4.21E+4nMAssay Description:Inhibition of heparanase (unknown origin) using biotin-heparan sulfate-Eu cryptate as substrate preincubated for 10 mins followed by substrate additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed