Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50019125
TargetCeramide glucosyltransferase(Mouse)
Emory University

Curated by ChEMBL
LigandPNGBDBM50615552(CHEMBL5266608)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of GSG in mouse MEB5 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHeparanase(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50615549(CHEMBL5279990)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of Heparanase (unknown origin) using heparan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHeparanase(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50615550(CHEMBL5267191)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Heparanase (unknown origin) using heparan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFatty acid synthase(Chicken)
Emory University

Curated by ChEMBL
LigandPNGBDBM50615540(CHEMBL5271377)
Affinity DataIC50: 1.56E+4nMAssay Description:Inhibition of Fatty acid synthase in chicken liver using [3H]-acetyl CoA as substrate preincubated for 30 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFatty acid synthase(Chicken)
Emory University

Curated by ChEMBL
LigandPNGBDBM50615541(CHEMBL5266900)
Affinity DataIC50: 1.56E+4nMAssay Description:Inhibition of Fatty acid synthase in chicken liver using [3H]-acetyl CoA as substrate preincubated for 30 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFatty acid synthase(Chicken)
Emory University

Curated by ChEMBL
LigandPNGBDBM50615542(CHEMBL5269517)
Affinity DataIC50: 1.56E+4nMAssay Description:Inhibition of Fatty acid synthase in chicken liver using [3H]-acetyl CoA as substrate preincubated for 30 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFatty acid synthase(Chicken)
Emory University

Curated by ChEMBL
LigandPNGBDBM50615543(CHEMBL5274276)
Affinity DataIC50: 1.56E+4nMAssay Description:Inhibition of Fatty acid synthase in chicken liver using [3H]-acetyl CoA as substrate preincubated for 30 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFatty acid synthase(Chicken)
Emory University

Curated by ChEMBL
LigandPNGBDBM50615544(CHEMBL5283434)
Affinity DataIC50: 1.56E+4nMAssay Description:Inhibition of Fatty acid synthase in chicken liver using [3H]-acetyl CoA as substrate preincubated for 30 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50615545(CHEMBL5266053)
Affinity DataIC50: 1.97E+4nMAssay Description:Inhibition of AKT1 (unknown origin) in presence of ATP by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50615548(CHEMBL5280505)
Affinity DataIC50: 3.08E+4nMAssay Description:Inhibition of AKT1 (unknown origin) in presence of ATP by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetCeramide glucosyltransferase(Mouse)
Emory University

Curated by ChEMBL
LigandPNGBDBM18355(N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of GSG in mouse MEB5 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50615546(CHEMBL5288424)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of AKT1 (unknown origin) in presence of ATP by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50615547(CHEMBL5268980)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of AKT1 (unknown origin) in presence of ATP by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Rabbit)
Emory University

Curated by ChEMBL
LigandPNGBDBM50615551(CHEMBL5268892)
Affinity DataKi:  18nMAssay Description:Inhibition of SERCA1a in rabbit Sarcoplasmic reticulum assessed as inhibition constant in presence of [gamma-32P]ATP and calcium ionophore A23187 by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Rabbit)
Emory University

Curated by ChEMBL
LigandPNGBDBM50453611(CHEMBL4207081)
Affinity DataKi:  19nMAssay Description:Inhibition of SERCA1a in rabbit Sarcoplasmic reticulum assessed as inhibition constant in presence of [gamma-32P]ATP and calcium ionophore A23187 by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed