Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50018979
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50614394(CHEMBL5273238)
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of heparanase (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50614394(CHEMBL5273238)
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of human heparanase using fondaparinux as substrate incubated for 18 hrs by Polymer-H fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50614397(CHEMBL5279386)
Affinity DataIC50: 12nMAssay Description:Inhibition of heparanase (unknown origin) incubated for 18 hrs by fondaparinux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50614398(CHEMBL5268939)
Affinity DataIC50: 20nMAssay Description:Inhibition of heparanase (unknown origin) incubated for 18 hrs by fondaparinux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetP-selectin(Mouse)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50614401(CHEMBL5269532)
Affinity DataIC50: 150nMAssay Description:Inhibition of mouse P-selectin assessed as inhibition of adhesion to human LS180 cells to immobilized P-selectin incubated for 1 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50147546(2-[3-(5-Benzo[1,3]dioxol-5-yl-benzooxazol-2-yl)-4-...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human heparanase assessed as reduction in basic fibroblast growth factor binding incubated for 2 hrs by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50165639(2-(2-(4-(3-(2,4-dichlorophenylamino)-3-oxoprop-1-e...)
Affinity DataIC50: 200nMAssay Description:Inhibition of heparanase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50412102(CHEMBL495255)
Affinity DataIC50: 200nMAssay Description:Inhibition of human heparanase assessed as reduction in basic fibroblast growth factor binding incubated for 2 hrs by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50614402(CHEMBL5285151)
Affinity DataIC50: 200nMAssay Description:Inhibition of human heparanase assessed as reduction in basic fibroblast growth factor binding incubated for 2 hrs by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50147534(1,3-dioxo-2-(3-(5-phenylbenzo[d]oxazol-2-yl)-4-(pr...)
Affinity DataIC50: 250nMAssay Description:Inhibition of human heparanase assessed as reduction in basic fibroblast growth factor binding incubated for 2 hrs by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50165652(2-(2-(4-(3-(4-bromophenyl)acrylamido)-3-fluorophen...)
Affinity DataIC50: 400nMAssay Description:Inhibition of human heparanase assessed as reduction in basic fibroblast growth factor binding incubated for 2 hrs by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50147537(2-{5-[5-(4-Fluoro-phenyl)-benzooxazol-2-yl]-2-meth...)
Affinity DataIC50: 400nMAssay Description:Inhibition of human heparanase assessed as reduction in basic fibroblast growth factor binding incubated for 2 hrs by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50165636(2-(4-(5-(4-(3-(4-bromophenyl)acrylamido)-2-chlorop...)
Affinity DataIC50: 400nMAssay Description:Inhibition of human heparanase assessed as reduction in basic fibroblast growth factor binding incubated for 2 hrs by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50614399(CHEMBL5266136)
Affinity DataIC50: 416nMAssay Description:Inhibition of heparanase (unknown origin) incubated for 18 hrs by fondaparinux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50165660(2-(3-(5-(4-chlorophenyl)benzo[d]oxazol-2-yl)-4-(pr...)
Affinity DataIC50: 500nMAssay Description:Inhibition of human heparanase assessed as reduction in basic fibroblast growth factor binding incubated for 2 hrs by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50614395(CHEMBL5279972)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of heparanase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50614400(CHEMBL5286425)
Affinity DataIC50: 4.82E+3nMAssay Description:Inhibition of heparanase (unknown origin) incubated for 18 hrs by fondaparinux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50147526(2-(3-Benzooxazol-2-yl-phenyl)-1,3-dioxo-indan-5-ca...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human heparanase assessed as reduction in basic fibroblast growth factor binding incubated for 2 hrs by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50147508(2-(2-methoxy-5-(5-(2-methoxyphenyl)benzo[d]oxazol-...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human heparanase assessed as reduction in basic fibroblast growth factor binding incubated for 2 hrs by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50614396(CHEMBL5270472)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of heparanase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50147532(2-[4-Methylamino-3-(5-phenyl-benzooxazol-2-yl)-phe...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human heparanase assessed as reduction in basic fibroblast growth factor binding incubated for 2 hrs by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50431651(CHEMBL2349236)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of heparanase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50093526(CHEMBL426373 | RK-682)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of heparanase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50614393(CHEMBL5279103)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of heparanase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50614392(CHEMBL276295)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of heparanase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50595401(CHEMBL5175115)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of heparanase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50179360(CHEMBL3040216)
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of heparanase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50611971(CHEMBL5280887)
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibition of heparanase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50614397(CHEMBL5279386)
Affinity DataKi:  6nMAssay Description:Binding affinity to heparanase (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed