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BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 748K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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75 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Current Trends in Psychedelic Science: Integrating Modified Lysergic Acid Derivatives and Psilocybin in Modern Medicine.EBI
Usona Institute
Advancements in Targeted Therapeutics: Integrating Metabolic Modulation, Immune Engineering, and Biologic Formulation Technologies.EBI
Usona Institute
Treatment of Metabolic Disorders Using Novel DGAT2 Inhibitors: Pyrazolopyridine and Triazolopyridine Derivatives.EBI
Usona Institute
Innovative Therapeutic Approaches Targeting K-Ras: Analysis of Macrocyclic Compounds, Peptidomimetics, and Pyridopyrimidine Inhibitors.EBI
Usona Institute
Toward Precision Oncology: The Role of TPD in Targeting CDK2 and Beyond.EBI
Usona Institute
Lysosomal Degradation of Extracellular Targets: Innovations and Implications.EBI
Usona Institute
Development and Utilization of Novel Transglutaminase 2 Inhibitors for Potential Treatment of Autoimmune Disease and Gastrointestinal Disorder.EBI
Usona Institute
Small-Molecule Heterocyclic Compounds: Gq-Biased Agonists for the 5-HT2A Receptor in Neuropsychiatric Treatment.EBI
Usona Institute
Expanding the Chemical Space: New Approach to Cell-Permeable Drugs.EBI
Usona Institute
PARP7 Inhibition: A Promising Pathway to Advancements in Cancer Therapy.EBI
Usona Institute
New Horizons in Cancer Treatment: A Closer Look at Novel PI3Kα Inhibitors.EBI
Usona Institute
Targeting KRASEBI
Usona Institute
Cyclin-Dependent Kinase Degradation via E3 Ligase Binding for Potential Disease Modulation in Cancer Treatment.EBI
Usona Institute
Unveiling New KRASEBI
Usona Institute
Innovative Therapeutic Strategies in TYK2-Targeted Treatments: From Cancer to Autoimmune Disorders.EBI
Usona Institute
Advancements in Predictive Medicine: NLRP3 Inflammasome Inhibitors and AI-Driven Predictive Health Analytics.EBI
Usona Institute
PROTAC: Harnessing Targeted Chimeras for Selective BCL-2 Degradation in Cancer Treatment.EBI
Usona Institute
Targeting the "Undruggable" Driver Protein, KRASEBI
Usona Institute
Discovery of Potent Deuterated Compounds as Potential KRASEBI
Usona Institute
Discovery of Selective and Potent KRASEBI
Usona Institute
Discovery of Selective Aldehyde Dehydrogenase Inhibitors for the Treatment of Cancer.EBI
Usona Institute
Restoration of Motor Function Post-Neurological Injury Using Serotonergic Agonist.EBI
Usona Institute
Ibogaine and Their Analogs as Therapeutics for Neurological and Psychiatric Disorders.EBI
Usona Institute
Application of Rapidly Accelerating Fibrosarcoma Protein Degraders in Drug Discovery.EBI
Usona Institute
KRAS Inhibitors and Target Engagement Technology: From Undruggable to Druggable Targets in Cancer Therapeutics.EBI
Usona Institute
3-Pyrrolidine-indole Derivatives as 5-HT2-Selective Receptor Modulators for the Potential Treatment of Mental Disorders.EBI
Usona Institute
Recent Discovery of PARP7 Inhibitors as Anticancer Agents.EBI
Usona Institute
ALK Inhibitors for Treating Cancer, Blood, and Kidney Diseases.EBI
Usona Institute
SARS-CoV-2: Novel Therapeutic Approaches for Diagnosis and Treatment.EBI
Usona Institute
Selective Cyclin-Dependent Kinase Inhibitors and Their Application in Cancer Therapy.EBI
Usona Institute
Improved 5-HT2 Selective Receptor Modulators for the Treatment of Psychological Disorders.EBI
Usona Institute
Small-Molecule Inhibitor of the Oncogenic KRASEBI
Usona Institute
Improved Metabolically Stable 5-HT Receptor Modulators and the Development of New Antidepressants.EBI
Usona Institute
Targeting KRAS G12D Mutant for the Potential Treatment of Pancreatic Cancer.EBI
Usona Institute
Targeting KRAS Mutant Protein Inhibitor for Potential Treatment in Cancer.EBI
Usona Institute
The Psychedelic Renaissance: Addressing Potential Adverse Effects in a Therapeutic Setting.EBI
Usona Institute
Targeting the KRAS G12D Mutant as Potential Therapy in Cancer.EBI
Usona Institute
Psilocin Derivatives as Serotonergic Psychedelic Agents for the Treatment of CNS Disorders.EBI
Usona Institute
Modulation of KRAS Mutant by Inhibiting PLK1 Kinase in Cancer Therapeutics.EBI
Usona Institute
Dual Inhibition of KRAS G12C and G12D Mutants as a Potential Treatment in Cancer Therapy.EBI
Usona Institute
Small Molecule Inhibitors of KRAS G12C Mutant.EBI
Usona Institute
Small Molecule Inhibitors of KRAS Mutant as a Therapeutic Strategy for the Treatment of Cancer.EBI
Usona Institute
Modulation of Androgen Receptor for Therapeutic Application in Cancer and Viral Infection.EBI
Usona Institute
Selective DYRK1A Inhibitor for the Treatment of Neurodegenerative Diseases: Alzheimer, Parkinson, Huntington, and Down Syndrome.EBI
Usona Institute
Methionine Adenosyltransferase Inhibitors for the Treatment of Cancer.EBI
Usona Institute
Targeting Stimulator of Interferon Genes (STING) for the Potential Treatment of Cancer and Infectious Diseases.EBI
Usona Institute
Tumor-Targeted Bivalent Protein Degradation for Application in Cancer Therapy.EBI
Usona Institute
Sigma-1 and Sigma-2 Receptor Modulators as Potential Therapeutics for Alzheimer's Disease.EBI
Usona Institute
Cyclin-Dependent Kinase Inhibitors in Cancer Therapeutics.EBI
Usona Institute
Estrogen Receptor Degrading PROTACS for the Treatment of Breast Cancer.EBI
Usona Institute
Ligand Design for Cereblon Based Immunomodulatory Therapy.EBI
Usona Institute
Synthesis and Biological Evaluation of Tryptamines Found in Hallucinogenic Mushrooms: Norbaeocystin, Baeocystin, Norpsilocin, and Aeruginascin.EBI
Usona Institute
PROTAC Molecules for the Treatment of Autoimmune Disorders.EBI
Usona Institute
Inhibitors of G12C Mutant Ras Proteins for the Treatment of Cancers.EBI
Usona Institute
Selective Estrogen Receptor Degraders for the Potential Treatment of Cancer.EBI
Usona Institute
Bifunctional Pyrimidines as Modulators of Focal Adhesion Kinase.EBI
Usona Institute
Cereblon Based Immunomodulatory Therapeutics.EBI
Usona Institute
Inhibition of ACSS2 for Treatment of Cancer and Neuropsychiatric Diseases.EBI
Usona Institute
Allosteric mGluREBI
Usona Institute
TRPV1 Modulators for the Treatment of Pain and Inflammation.EBI
Usona Institute
Allosteric CBEBI
Usona Institute
Heterocyclic Amides as Kinase Inhibitors.EBI
Usona Institute
Modulation of Tropomyosin Receptor Kinase for the Treatment of Neurotrophin Diseases: Alzheimer's, Huntington's and Parkinson's.EBI
Usona Institute
PROTAC-Mediated Degradation of Estrogen Receptor in the Treatment of Cancer.EBI
Usona Institute
PROTAC Degradation of IRAK4 for the Treatment of Neurodegenerative and Cardiovascular Diseases.EBI
Usona Institute
Treatment of Cancers by Inhibition of Isoprenylcysteine Carboxyl Methyltransferase.EBI
Usona Institute
NLRP3 Modulators for the Treatment of Autoinflammatory Disorders.EBI
Usona Institute
Toll-like Receptors for the Treatment of Autoimmune, Inflammation, and Infectious Diseases.EBI
Usona Institute
Thiazole Derivatives as Inhibitors for the Treatment of Cancer Cells Resistant.EBI
Usona Institute
Histone Deacetylase Inhibitors as Treatment for Targeting Multiple Components in Cancer Therapy.EBI
Usona Institute
5-HTEBI
Usona Institute
Allosteric Modulators of the M4 Muscarinic Acetylcholine Receptor.EBI
Usona Institute
Modulators of the Cystic Fibrosis Transmembrane Conductance Regulator Protein.EBI
Usona Institute
2,7-Diazaspiro[4,4]nonanes for the Treatment or Prevention of Cancers and Diabetes.EBI
Usona Institute
Ubiquitin-Specific Inhibitors for the Treatment of Cancers, Autoimmune, and Infectious Diseases.EBI
Usona Institute