Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50010759
TargetBromodomain-containing protein 4(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50541818(CHEMBL4648907 | US11530219, Compound 16)
Affinity DataIC50: 517nMAssay Description:Inhibition of BRD4 bromodomain 2 (unknown origin) in HEK293 cells cotransfected with eGFP by flow cytometry based mCherry reporter gene analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50541817(CHEMBL4635421 | US11530219, Compound 14)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of BRD4 bromodomain 2 (unknown origin) in HEK293 cells cotransfected with eGFP by flow cytometry based mCherry reporter gene analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50541820(CHEMBL4648134)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of BRD4 bromodomain 2 (unknown origin) in HEK293 cells cotransfected with eGFP by flow cytometry based mCherry reporter gene analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50541819(CHEMBL4645406 | US11530219, Compound 17)
Affinity DataIC50: 3.44E+3nMAssay Description:Inhibition of BRD4 bromodomain 2 (unknown origin) in HEK293 cells cotransfected with eGFP by flow cytometry based mCherry reporter gene analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM65454(Lenalidomide | US9694015, 6.1 | 191732-72-6 | Revl...)
Affinity DataIC50: 5.19E+3nMAssay Description:Inhibition of BRD4 bromodomain 2 (unknown origin) in HEK293 cells cotransfected with eGFP by flow cytometry based mCherry reporter gene analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50541821(CHEMBL4639892)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of BRD4 bromodomain 2 (unknown origin) in HEK293 cells cotransfected with eGFP by flow cytometry based mCherry reporter gene analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetProtein cereblon(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50541818(CHEMBL4648907 | US11530219, Compound 16)
Affinity DataKi:  130nMAssay Description:Binding affinity to CBRN (unknown origin) incubated for 60 mins by lenalidomide displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetProtein cereblon(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50541817(CHEMBL4635421 | US11530219, Compound 14)
Affinity DataKi:  440nMAssay Description:Binding affinity to CBRN (unknown origin) incubated for 60 mins by lenalidomide displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetProtein cereblon(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50541820(CHEMBL4648134)
Affinity DataKi:  800nMAssay Description:Binding affinity to CBRN (unknown origin) incubated for 60 mins by lenalidomide displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetProtein cereblon(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50541819(CHEMBL4645406 | US11530219, Compound 17)
Affinity DataKi:  970nMAssay Description:Binding affinity to CBRN (unknown origin) incubated for 60 mins by lenalidomide displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetProtein cereblon(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM65454(Lenalidomide | US9694015, 6.1 | 191732-72-6 | Revl...)
Affinity DataKi:  1.49E+3nMAssay Description:Binding affinity to CBRN (unknown origin) incubated for 60 mins by lenalidomide displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetProtein cereblon(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50541821(CHEMBL4639892)
Affinity DataKi:  2.20E+3nMAssay Description:Binding affinity to CBRN (unknown origin) incubated for 60 mins by lenalidomide displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed