Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50020193
TargetGTPase KRas(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50627207(CHEMBL5428155)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of KRAS G12D mutant in human PANC-1 cells assessed as reduction in phosphorylation of ERK 1/2 level incubated for 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetGTPase KRas(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50627208(CHEMBL5394061)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of KRAS G12D mutant in human PANC-1 cells assessed as reduction in phosphorylation of ERK 1/2 level incubated for 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetGTPase KRas(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50627205(CHEMBL5406644)
Affinity DataIC50: 15nMAssay Description:Inhibition of KRAS G12D mutant in human PANC-1 cells assessed as reduction in phosphorylation of ERK 1/2 level incubated for 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetGTPase KRas(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50627209(CHEMBL5405893)
Affinity DataIC50: 24nMAssay Description:Inhibition of KRAS G12D mutant in human PANC-1 cells assessed as reduction in phosphorylation of ERK 1/2 level incubated for 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetGTPase KRas(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50627212(CHEMBL5398980)
Affinity DataIC50: 40nMAssay Description:Inhibition of KRAS G12D mutant in human PANC-1 cells assessed as reduction in phosphorylation of ERK 1/2 level incubated for 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetGTPase KRas(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50627206(CHEMBL5401145)
Affinity DataIC50: 46nMAssay Description:Inhibition of KRAS G12D mutant in human PANC-1 cells assessed as reduction in phosphorylation of ERK 1/2 level incubated for 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetGTPase KRas(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50627211(CHEMBL5430597)
Affinity DataIC50: 305nMAssay Description:Inhibition of KRAS G12D mutant in human PANC-1 cells assessed as reduction in phosphorylation of ERK 1/2 level incubated for 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetGTPase KRas(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50627210(CHEMBL5430615)
Affinity DataIC50: 439nMAssay Description:Inhibition of KRAS G12D mutant in human PANC-1 cells assessed as reduction in phosphorylation of ERK 1/2 level incubated for 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed