BDBM648426 US20240033256, Compound 1

SMILES COc1cc2c3CC4CCCN4Cc3c3cc(OC)c(OC)cc3c2cc1OC

InChI Key InChIKey=SSEUDFYBEOIWGF-UHFFFAOYSA-N

Data  7 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 648426   

TargetReplicase polyprotein 1ab(2019-nCoV)
National Health Research Institutes

US Patent
LigandPNGBDBM648426(US20240033256, Compound 1)
Affinity DataEC50:  76.8nMAssay Description:Vero E6 cells derived from BCRC #60476 (Bioresource Collection and Research Center, Hsinchu, Taiwan) were treated with each compound at an indicated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
National Health Research Institutes

US Patent
LigandPNGBDBM648426(US20240033256, Compound 1)
Affinity DataEC50:  64nMAssay Description:Vero E6 cells derived from BCRC #60476 (Bioresource Collection and Research Center, Hsinchu, Taiwan) were treated with each compound at an indicated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetReplicase polyprotein 1ab(HCoV-OC43)
National Health Research Institutes

US Patent
LigandPNGBDBM648426(US20240033256, Compound 1)
Affinity DataEC50:  68nMAssay Description:Human colon adenocarcinoma cell line HCT-8 (ATCC@ CCL-244, American Type Culture Collection, Manassas, VA, USA) was obtained from American Type Cultu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetReplicase polyprotein 1ab(HCoV-229E)
National Health Research Institutes

US Patent
LigandPNGBDBM648426(US20240033256, Compound 1)
Affinity DataEC50:  71.4nMAssay Description:HCoV-229E viral genome replication was examined by RT-PCR with specific primers against its open reading frame 1 (“ORF1”) and ORF nucleocap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetGenome polyprotein(ZIKV)
National Health Research Institutes

US Patent
LigandPNGBDBM648426(US20240033256, Compound 1)
Affinity DataEC50:  61.4nMAssay Description:Vero E6 cells (BCRC #60476, Bioresource Collection and Research Center, Hsinchu, Taiwan) were treated with one of Compounds 1-9 at a predetermined co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetGenome polyprotein(DENV-1)
National Health Research Institutes

US Patent
LigandPNGBDBM648426(US20240033256, Compound 1)
Affinity DataEC50:  18.4nMAssay Description:Vero E6 cells (BCRC #60476, Bioresource Collection and Research Center, Hsinchu, Taiwan) were treated with one of Compounds 1-9 at a predetermined co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetGenome polyprotein(DENV-2)
National Health Research Institutes

US Patent
LigandPNGBDBM648426(US20240033256, Compound 1)
Affinity DataEC50:  32.5nMAssay Description:Vero E6 cells (BCRC #60476, Bioresource Collection and Research Center, Hsinchu, Taiwan) were treated with one of Compounds 1-9 at a predetermined co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent