The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.1M data for 1.3M Compounds and 9.6K Targets. Of those, 1.5M data for 698K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

If BindingDB was of value to your research, please take a moment to donate to this nonprofit project. Your donation will let us provide you with more data and improved service.

To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

64 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
New arylalkanones from Horsfieldia macrobotrys, effective antidiabetic agents concomitantly inhibitinga-glucosidase and free radicals.EBI
Chulalongkorn University
Lanostane Triterpenes from the Tibetan Medicinal Mushroom Ganoderma leucocontextum and Their Inhibitory Effects on HMG-CoA Reductase anda-Glucosidase.EBI
Chinese Academy of Sciences
Polyketides witha-Glucosidase Inhibitory Activity from a Mangrove Endophytic Fungus, Penicillium sp. HN29-3B1.EBI
Hebei University
Synthesis and biological evaluation ofa-1-C-4'-arylbutyl-L-arabinoiminofuranoses, a new class ofa-glucosidase inhibitors.EBI
Tohoku Pharmaceutical University
Quercitylcinnamates, a new series of antidiabetic bioconjugates possessinga-glucosidase inhibition and antioxidant.EBI
Chulalongkorn University
Synthesis anda-glucosidase inhibitory activity evaluation of N-substituted aminomethyl-ß-d-glucopyranosides.EBI
Xi'An Jiaotong University
A new series of N2-substituted-5-(p-toluenesulfonylamino)phthalimide analogues asa-glucosidase inhibitors.EBI
Xi'An Jiaotong University
Synthesis, crystal structure and antidiabetic activity of substituted (E)-3-(Benzo [d]thiazol-2-ylamino) phenylprop-2-en-1-one.EBI
North Maharashtra University
Synthesis and glycosidase inhibitory activity of novel (2-phenyl-4H-benzopyrimedo[2,1-b]-thiazol-4-yliden)acetonitrile derivatives.EBI
North Maharashtra University
a-1-C-butyl-1,4-dideoxy-1,4-imino-l-arabinitol as a second-generation iminosugar-based orala-glucosidase inhibitor for improving postprandial hyperglycemia.EBI
University of Toyama
Discovery of a novel noniminosugar acida glucosidase chaperone series.EBI
National Center For Advancing Translational Sciences
Role of the side chain stereochemistry in thea-glucosidase inhibitory activity of kotalanol, a potent naturala-glucosidase inhibitor. Part 2.EBI
Kinki University
(+)-Pinoresinol is a putative hypoglycemic agent in defatted sesame (Sesamum indicum) seeds though inhibitinga-glucosidase.EBI
Chulalongkorn University
Isolation, structure identification and SAR studies on thiosugar sulfonium salts, neosalaprinol and neoponkoranol, as potenta-glucosidase inhibitors.EBI
Kinki University
Alpha-glucosidase inhibitor from Kothala-himbutu (Salacia reticulata WIGHT).EBI
Fuji-Sangyo
In vitro inhibition of glycogen-degrading enzymes and glycosidases by six-membered sugar mimics and their evaluation in cell cultures.EBI
Hokuriku University
Iminosugar-producing Thai medicinal plants.EBI
Hokuriku University
Synthesis and biological evaluation of novel 8-aminomethylated oroxylin A analogues as alpha-glucosidase inhibitors.EBI
Indian Institute of Chemical Technology
Homonojirimycin isomers and N-alkylated homonojirimycins: structural and conformational basis of inhibition of glycosidases.EBI
Hokuriku University
Nitrogen-in-the-ring pyranoses and furanoses: structural basis of inhibition of mammalian glycosidases.EBI
Hokuriku University
Homoisofagomines: chemical-enzymatic synthesis and evaluation as alpha- and beta-glucosidase inhibitors.EBI
Technische Universit£T Berlin
A new strong inhibitor of beta-mannosidase.EBI
S.E.S.N.A.B., Pole Sciences Et Technologie, Universit�
 
Inhibition of glycosidases by substituted amidinesEBI
TBA
 
Sulfoquinovosyldiacylglycerol as an -glucosidase inhibitorEBI
TBA
 
Potent glycosidase inhibitors, N-phenyl cyclic isourea derivatives of 5-amino- and 5-amino-1-C-(hydroxymethyl)-cyclopentane-1,2,3,4-tetraolsEBI
TBA
Concise synthesis of (+)-conduritol F and inositol analogues from naturally available (+)-proto-quercitol and their glucosidase inhibitory activity.EBI
Chulalongkorn University
Antidiabetogenic oligostilbenoids and 3-ethyl-4-phenyl-3,4-dihydroisocoumarins from the bark of Shorea roxburghii.EBI
Kinki University
Biological evaluation of 3'-O-alkylated analogs of salacinol, the role of hydrophobic alkyl group at 3' position in the side chain on thea-glucosidase inhibitory activity.EBI
Kinki University
Role of the side chain stereochemistry in thea-glucosidase inhibitory activity of kotalanol, a potent naturala-glucosidase inhibitor.EBI
Kinki University
Selectivea-glucosidase substrates and inhibitors containing short aromatic peptidyl moieties.EBI
Seoul National University
Identification of Potent and Selective Glucosylceramide Synthase Inhibitors from a Library of N-Alkylated IminosugarsEBI
TBA
The synthesis and biological evaluation of 1-C-alkyl-L-arabinoiminofuranoses, a novel class ofa-glucosidase inhibitors.EBI
Tohoku Pharmaceutical University
Dual-action lipophilic iminosugar improves glycemic control in obese rodents by reduction of visceral glycosphingolipids and buffering of carbohydrate assimilation.EBI
Leiden University
Total synthesis of (-)-uniflorine A.EBI
University of Florence
Synthesis and evaluation of D-gluco-pyranocyclopropyl amines as potential glucosidase inhibitors.EBI
Leiden University
Synthetic studies in butenonyl C-glycosides: Preparation of polyfunctional alkanonyl glycosides and their enzyme inhibitory activity.EBI
Central Drug Research Institute
 
New deoxynojirimycin derivatives as potent inhibitors of intestinal α-glucohydrolasesEBI
TBA
 
Synthesis of a new inhibitor of α-fucosidaseEBI
TBA
 
Synthesis of C2-symmetrical polyhydroxyazepanes as inhibitors of glycosidasesEBI
TBA
Glycosidase-inhibiting pyrrolidines and pyrrolizidines with a long side chain in Scilla peruviana.EBI
Hokuriku University
New polyhydroxylated pyrrolidine, piperidine, and pyrrolizidine alkaloids from Scilla sibirica.EBI
Hokuriku University
New sugar-mimic alkaloids from the pods of Angylocalyx pynaertii.EBI
Hokuriku University
Nitrogen-containing furanose and pyranose analogues from Hyacinthus orientalis.EBI
Hokuriku University
Design and Pharmacological Chaperone Effects of EBI
University of Toyama
Synthesis of the Purported Structure of Glyphaeaside C and Proposed Revisions to the Structures of the Glyphaeaside Alkaloids.EBI
University of Wollongong
Design and Synthesis of Sulfonium Derivatives: A Novel Class of α-Glucosidase Inhibitors with Potent In Vivo Antihyperglycemic Activities.EBI
China Pharmaceutical University
Harnessing polyhydroxylated pyrrolidines as a stabilizer of acid alpha-glucosidase (GAA) to enhance the efficacy of enzyme replacement therapy in Pompe disease.EBI
National Yang Ming Chiao Tung University
trans, trans-2-C-Aryl-3,4-dihydroxypyrrolidines as potent and selective β-glucosidase inhibitors: Pharmacological chaperones for Gaucher disease.EBI
Chinese Academy of Sciences
Design, synthesis and glycosidase inhibition of C-4 branched LAB and DAB derivatives.EBI
Chinese Academy of Sciences
5-EBI
University of Toyama
Glycosidase inhibition by cyclic sulfonium compounds.EBI
Graduate School of Bioscience and Biotechnology
Isotope edited NMR studies of glycosidases: design and synthesis of a novel glycosidase inhibitor.EBI
Ohio State University
Corrected Structure of Natural Hyacinthacine CEBI
University of Wollongong
Phenolic and triterpene glycosides from the stems of Ilex litseaefolia.EBI
Chinese Academy of Sciences
Callyspongynic acid, a polyacetylenic acid which inhibits alpha-glucosidase, from the marine sponge Callyspongia truncata.EBI
The University of Tokyo
Synthesis, in vitro evaluation and molecular docking studies of novel triazine-triazole derivatives as potentialα-glucosidase inhibitors.EBI
Jishou University
N-Butyl-l-deoxynojirimycin (l-NBDNJ): Synthesis of an Allosteric Enhancer ofα-Glucosidase Activity for the Treatment of Pompe Disease.EBI
University of Naples Federico II
Plasma Kallikrein inhibitors and uses thereofBDB
Takeda Pharmaceutical
Substituted imidazopyridines as HDM2 inhibitorsBDB
Merck Sharp & Dohme
[(pF)Phe4,Arg14,Lys15]N/OFQ-NH2 (UFP-102), a highly potent and selective agonist of the nociceptin/orphanin FQ receptor.BDB
Section of Pharmacology