Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50045168
TargetSucrase-isomaltase, intestinal(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50048090(CHEMBL3311519)
Affinity DataIC50: 26nMAssay Description:Inhibition of Wistar rat intestinal sucrase assessed as inhibition of D-glucose release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50333455((2S,3S,4S,5S)-2-butyl-5-(hydroxymethyl)pyrrolidine...)
Affinity DataIC50: 32nMAssay Description:Inhibition of Wistar rat intestinal sucrase assessed as inhibition of D-glucose release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50048086(CHEMBL3311515)
Affinity DataIC50: 45nMAssay Description:Inhibition of Wistar rat intestinal sucrase assessed as inhibition of D-glucose release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50048087(CHEMBL3311516)
Affinity DataIC50: 110nMAssay Description:Inhibition of Wistar rat intestinal maltase assessed as inhibition of D-glucose release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50048088(CHEMBL3311517)
Affinity DataIC50: 110nMAssay Description:Inhibition of Wistar rat intestinal sucrase assessed as inhibition of D-glucose release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50263044(Voglibose | CHEMBL476960)
Affinity DataIC50: 120nMAssay Description:Inhibition of Wistar rat intestinal maltase assessed as inhibition of D-glucose release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50333455((2S,3S,4S,5S)-2-butyl-5-(hydroxymethyl)pyrrolidine...)
Affinity DataIC50: 130nMAssay Description:Inhibition of Wistar rat intestinal maltase assessed as inhibition of D-glucose release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50048087(CHEMBL3311516)
Affinity DataIC50: 130nMAssay Description:Inhibition of Wistar rat intestinal sucrase assessed as inhibition of D-glucose release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50048089(CHEMBL3311518)
Affinity DataIC50: 170nMAssay Description:Inhibition of Wistar rat intestinal sucrase assessed as inhibition of D-glucose release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50048088(CHEMBL3311517)
Affinity DataIC50: 170nMAssay Description:Inhibition of Wistar rat intestinal maltase assessed as inhibition of D-glucose release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 180nMAssay Description:Inhibition of Wistar rat intestinal maltase assessed as inhibition of D-glucose release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50048089(CHEMBL3311518)
Affinity DataIC50: 180nMAssay Description:Inhibition of Wistar rat intestinal maltase assessed as inhibition of D-glucose release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50399655(CHEMBL2177690)
Affinity DataIC50: 220nMAssay Description:Inhibition of Wistar rat intestinal maltase assessed as inhibition of D-glucose release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50048090(CHEMBL3311519)
Affinity DataIC50: 220nMAssay Description:Inhibition of Wistar rat intestinal isomaltase assessed as inhibition of D-glucose release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50048086(CHEMBL3311515)
Affinity DataIC50: 280nMAssay Description:Inhibition of Wistar rat intestinal maltase assessed as inhibition of D-glucose release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50399655(CHEMBL2177690)
Affinity DataIC50: 310nMAssay Description:Inhibition of Wistar rat intestinal sucrase assessed as inhibition of D-glucose release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50048090(CHEMBL3311519)
Affinity DataIC50: 340nMAssay Description:Inhibition of Wistar rat intestinal maltase assessed as inhibition of D-glucose release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50263044(Voglibose | CHEMBL476960)
Affinity DataIC50: 370nMAssay Description:Inhibition of Wistar rat intestinal sucrase assessed as inhibition of D-glucose release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50048086(CHEMBL3311515)
Affinity DataIC50: 630nMAssay Description:Inhibition of Wistar rat intestinal isomaltase assessed as inhibition of D-glucose release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50242271(Glyset | N-Hydroxyethyl-1-deoxynojirimycin | CHEMB...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Wistar rat intestinal sucrase assessed as inhibition of D-glucose release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50242271(Glyset | N-Hydroxyethyl-1-deoxynojirimycin | CHEMB...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Wistar rat intestinal maltase assessed as inhibition of D-glucose release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSucrase-isomaltase, intestinal(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50048087(CHEMBL3311516)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of Wistar rat intestinal isomaltase assessed as inhibition of D-glucose release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of Wistar rat intestinal sucrase assessed as inhibition of D-glucose release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50048089(CHEMBL3311518)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of Wistar rat intestinal isomaltase assessed as inhibition of D-glucose release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50333455((2S,3S,4S,5S)-2-butyl-5-(hydroxymethyl)pyrrolidine...)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of Wistar rat intestinal isomaltase assessed as inhibition of D-glucose release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50263044(Voglibose | CHEMBL476960)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of Wistar rat intestinal isomaltase assessed as inhibition of D-glucose release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50048088(CHEMBL3311517)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of Wistar rat intestinal isomaltase assessed as inhibition of D-glucose release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50399655(CHEMBL2177690)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of Wistar rat intestinal isomaltase assessed as inhibition of D-glucose release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50242271(Glyset | N-Hydroxyethyl-1-deoxynojirimycin | CHEMB...)
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of Wistar rat intestinal isomaltase assessed as inhibition of D-glucose release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed