Binding Database

The following articles (labelled with PubMed ID or TBD) are for your review

PMID

Data

Article Title

Organization

Acetyl-Click Screening Platform Identifies Small-Molecule Inhibitors of Histone Acetyltransferase 1 (HAT1).

Wayne State University

First-in-Class Selective Inhibitors of the Lysine Acetyltransferase KAT8.

Sapienza University of Rome

Discovery of DS-9300: A Highly Potent, Selective, and Once-Daily Oral EP300/CBP Histone Acetyltransferase Inhibitor.

Daiichi Sankyo Co.

Discovery of EP300/CBP histone acetyltransferase inhibitors through scaffold hopping of 1,4-oxazepane ring.

Daiichi Sankyo

Design, synthesis and biological evaluation of a novel spiro oxazolidinedione as potent p300/CBP HAT inhibitor for the treatment of ovarian cancer.

China Pharmaceutical University

4-Pyridone-3-carboxylic acid as a benzoic acid bioisostere: Design, synthesis, and evaluation of EP300/CBP histone acetyltransferase inhibitors.

Daiichi Sankyo

Histone acetyltransferase inhibitors: An overview in synthesis, structure-activity relationship and molecular mechanism.

Sichuan University

Discovery of Highly Potent, Selective, and Orally Efficacious p300/CBP Histone Acetyltransferases Inhibitors.

Chinese Academy of Sciences

Substituted heterocycles as aldehyde dehydrogenase inhibitors

Kayothera

Isoquinolin-3-yl carboxamides and preparation and use thereof

Biosplice Therapeutics

Mu opioid receptor modulators

University of California

Methylamine derivatives as lysysl oxidase inhibitors for the treatment of cancer

The Institute of Cancer Research: Royal Cancer Hospital