Compile Data Set for Download or QSAR
Report error Found 46 Enz. Inhib. hit(s) with all data for entry = 50009383
TargetCREB-binding protein(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50456444(CHEMBL3734823)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of CBP BHC domain (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT6A [507-778](Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50518832(CHEMBL4455897 | US10829446, Compound 36)
Affinity DataIC50: 8nMAssay Description:Inhibition of KAT6A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50456444(CHEMBL3734823)
Affinity DataIC50: 9.80nMAssay Description:Inhibition of P300 BHC domain (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50528248(CHEMBL4524766)
Affinity DataIC50: 11nMAssay Description:Displacement of [3H]-acetyl-CoA from recombinant GST-tagged P300 (unknown origin) by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50528248(CHEMBL4524766)
Affinity DataIC50: 11nMAssay Description:Displacement of [3H]-acetyl-CoA from recombinant GST-tagged P300 (unknown origin) after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50528262(CHEMBL4447371)
Affinity DataIC50: 22nMAssay Description:Displacement of [3H]-acetyl-CoA from recombinant GST-tagged P300 (unknown origin) by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT6B(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50518832(CHEMBL4455897 | US10829446, Compound 36)
Affinity DataIC50: 28nMAssay Description:Inhibition of KAT6B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50528249(CHEMBL4573224)
Affinity DataIC50: 420nMAssay Description:Displacement of [3H]-acetyl-CoA from P300 (unknown origin) using peptide as substrate after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50528253(CHEMBL4579084)
Affinity DataIC50: 750nMAssay Description:Inhibition of P300 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50528253(CHEMBL4579084)
Affinity DataIC50: 750nMAssay Description:Displacement of [3H]-acetyl-CoA from P300 in human HeLa cells using peptide as substrate after 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50528247(CHEMBL4465296)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human P300 (1284 to1673 residues) catalytic domain expressed in Escherichia coli by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50456444(CHEMBL3734823)
Affinity DataIC50: 1.60E+3nMAssay Description:Noncompetitive inhibition of P300 (1287 to 1652 residues) VMA intein chitin binding domain (unknown origin) expressed in Escherichia coli BL21(RIL)-D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50456444(CHEMBL3734823)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of P300 (unknown origin) (1287 to 1652 residues) expressed in Escherichia coli BL21(RIL)-DE3 cells using [12C]-acetyl-CoA/[14C]-acetyl-CoA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50528261(CHEMBL4591290)
Affinity DataIC50: 1.80E+3nMAssay Description:Displacement of [3H]-acetyl-CoA from P300 (unknown origin) using peptide as substrate after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50528252(CHEMBL4461297)
Affinity DataIC50: 1.80E+3nMAssay Description:Displacement of [3H]-acetyl-CoA from P300 (unknown origin) using peptide as substrate after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50528243(CHEMBL4564898)
Affinity DataIC50: 1.80E+3nMAssay Description:Displacement of [3H]-acetyl-CoA from P300 (unknown origin) using peptide as substrate after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50151658(CHEMBL3775671)
Affinity DataIC50: 1.98E+3nMAssay Description:Inhibition of P300 (unknown origin) using histone H3 as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50528246(CHEMBL4468817)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of P300 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT5(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50151660(CHEMBL3774630)
Affinity DataIC50: 2.00E+3nMAssay Description:Displacement of [3H]-acetyl-CoA from recombinant Tip60 (unknown origin) by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT5(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50151660(CHEMBL3774630)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Tip60 (unknown origin) using [3H]-acetyl-CoA as substrate preincubated for 10 mins followed by substrate addition measured after 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT2B(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50528257(CHEMBL4590729)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of recombinant GST-tagged PCAF (32 residues) (unknown origin) expressed in Escherichia coli using radiolabelled acetyl-CoA as substrate af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50528259(CHEMBL4446385)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of P300 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50528245(CHEBI:9419 | taxodione)
Affinity DataIC50: 4.85E+3nMAssay Description:Inhibition of P300 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50528256(CHEMBL4446656)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of P300 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50528244(CHEMBL4456463)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of P300 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50528242(CHEMBL4516760)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of P300 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50528256(CHEMBL4446656)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of P300 (unknown origin) assessed as reduction in p53 acetylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50528258(CHEMBL4466490)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]-acetyl-CoA from P300 (unknown origin) using peptide as substrate after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50528250(CHEMBL4538233)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]-acetyl-CoA from P300 (unknown origin) using peptide as substrate after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50528251(CHEMBL4536287)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]-acetyl-CoA from P300 (unknown origin) using peptide as substrate after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50528260(CHEMBL4457203)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]-acetyl-CoA from P300 (unknown origin) using peptide as substrate after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50528255(CHEMBL4455088)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]-acetyl-CoA from P300 (unknown origin) using peptide as substrate after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50012070(CHEMBL295316 | plumbagin | 5-hydroxy-2-methylnapht...)
Affinity DataIC50: 2.00E+4nMAssay Description:Displacement of [3H]-acetyl-CoA from recombinant P300 (unknown origin) expressed in baculovirus expression system preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50012070(CHEMBL295316 | plumbagin | 5-hydroxy-2-methylnapht...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of P300 in human HeLa cells using [3H]-acetyl-CoA as substrate preincubated for 10 mins followed by substrate addition measured after 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetCREB-binding protein/Histone acetyltransferase p300(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50140172(CHEBI:3962 | CHEMBL140 | Curcumin | US9409845, Tab...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of p300 (unknown origin)/CBP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetCREB-binding protein/Histone acetyltransferase p300(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50326997(CHEMBL590878 | Delphinidin)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of p300 (unknown origin)/CBP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50151658(CHEMBL3775671)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of P300 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50070942((-)-Epigallocatechin-3-o-gallate | (-)-Epigallocat...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of P300 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT2B(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50012070(CHEMBL295316 | plumbagin | 5-hydroxy-2-methylnapht...)
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of [3H]-acetyl-CoA from recombinant PCAF (unknown origin) expressed in baculovirus expression system preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT2B(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50012070(CHEMBL295316 | plumbagin | 5-hydroxy-2-methylnapht...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of PCAF in human HeLa cells using [3H]-acetyl-CoA as substrate preincubated for 10 mins followed by substrate addition measured after 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetCREB-binding protein(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50070942((-)-Epigallocatechin-3-o-gallate | (-)-Epigallocat...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CBP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50528254(CHEMBL4515219)
Affinity DataIC50: 5.75E+4nMAssay Description:Inhibition of P300 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT2B(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50070942((-)-Epigallocatechin-3-o-gallate | (-)-Epigallocat...)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of PCAF (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT5(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50070942((-)-Epigallocatechin-3-o-gallate | (-)-Epigallocat...)
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of Tip60 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT5(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50518801(CHEMBL4470091)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of KAT5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT7(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50518801(CHEMBL4470091)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of KAT7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed