Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50014905
TargetHistone acetyltransferase p300(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580965(CHEMBL5090239)
Affinity DataIC50: 0.490nMAssay Description:Inhibition of p300 (unknown origin) preincubated for 15 mins followed by addition of substrate [3H] Ac-CoA and measured after 60 mins by liquid scint...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580965(CHEMBL5090239)
Affinity DataIC50: 0.510nMAssay Description:Inhibition of p300 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580962(CHEMBL5082755)
Affinity DataIC50: 0.560nMAssay Description:Inhibition of p300 (unknown origin) preincubated for 15 mins followed by addition of substrate [3H] Ac-CoA and measured after 60 mins by liquid scint...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50506372(CHEMBL4475351)
Affinity DataIC50: 0.950nMAssay Description:Inhibition of p300 (unknown origin) preincubated for 15 mins followed by addition of substrate [3H] Ac-CoA and measured after 60 mins by liquid scint...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580968(CHEMBL5083020)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of p300 (unknown origin) preincubated for 15 mins followed by addition of substrate [3H] Ac-CoA and measured after 60 mins by liquid scint...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580963(CHEMBL5077158)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of p300 (unknown origin) preincubated for 15 mins followed by addition of substrate [3H] Ac-CoA and measured after 60 mins by liquid scint...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50506366(CHEMBL4524352)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of p300 (unknown origin) preincubated for 15 mins followed by addition of substrate [3H] Ac-CoA and measured after 60 mins by liquid scint...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580964(CHEMBL5094423)
Affinity DataIC50: 4nMAssay Description:Inhibition of p300 (unknown origin) preincubated for 15 mins followed by addition of substrate [3H] Ac-CoA and measured after 60 mins by liquid scint...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCREB-binding protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580962(CHEMBL5082755)
Affinity DataIC50: 7nMAssay Description:Inhibition of CBP (unknown origin) preincubated for 15 mins followed by addition of substrate [3H] Ac-CoA and measured after 60 mins by liquid scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCREB-binding protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580965(CHEMBL5090239)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of CBP (unknown origin) preincubated for 15 mins followed by addition of substrate [3H] Ac-CoA and measured after 60 mins by liquid scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCREB-binding protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50506372(CHEMBL4475351)
Affinity DataIC50: 8.10nMAssay Description:Inhibition of CBP (unknown origin) preincubated for 15 mins followed by addition of substrate [3H] Ac-CoA and measured after 60 mins by liquid scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCREB-binding protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580968(CHEMBL5083020)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of CBP (unknown origin) preincubated for 15 mins followed by addition of substrate [3H] Ac-CoA and measured after 60 mins by liquid scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580974(CHEMBL5078353)
Affinity DataIC50: 8.60nMAssay Description:Inhibition of p300 (unknown origin) preincubated for 15 mins followed by addition of substrate [3H] Ac-CoA and measured after 60 mins by liquid scint...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580970(CHEMBL5081689)
Affinity DataIC50: 8.60nMAssay Description:Inhibition of p300 (unknown origin) preincubated for 15 mins followed by addition of substrate [3H] Ac-CoA and measured after 60 mins by liquid scint...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580972(CHEMBL5078021)
Affinity DataIC50: 9.80nMAssay Description:Inhibition of p300 (unknown origin) preincubated for 15 mins followed by addition of substrate [3H] Ac-CoA and measured after 60 mins by liquid scint...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580971(CHEMBL5085891)
Affinity DataIC50: 10nMAssay Description:Inhibition of p300 (unknown origin) preincubated for 15 mins followed by addition of substrate [3H] Ac-CoA and measured after 60 mins by liquid scint...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580967(CHEMBL5083262)
Affinity DataIC50: 11nMAssay Description:Inhibition of p300 (unknown origin) preincubated for 15 mins followed by addition of substrate [3H] Ac-CoA and measured after 60 mins by liquid scint...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580969(CHEMBL5073432)
Affinity DataIC50: 12nMAssay Description:Inhibition of p300 (unknown origin) preincubated for 15 mins followed by addition of substrate [3H] Ac-CoA and measured after 60 mins by liquid scint...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCREB-binding protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580964(CHEMBL5094423)
Affinity DataIC50: 12nMAssay Description:Inhibition of CBP (unknown origin) preincubated for 15 mins followed by addition of substrate [3H] Ac-CoA and measured after 60 mins by liquid scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580973(CHEMBL5084035)
Affinity DataIC50: 13nMAssay Description:Inhibition of p300 (unknown origin) preincubated for 15 mins followed by addition of substrate [3H] Ac-CoA and measured after 60 mins by liquid scint...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCREB-binding protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580963(CHEMBL5077158)
Affinity DataIC50: 14nMAssay Description:Inhibition of CBP (unknown origin) preincubated for 15 mins followed by addition of substrate [3H] Ac-CoA and measured after 60 mins by liquid scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50467836(CHEMBL4282264)
Affinity DataIC50: 15nMAssay Description:Inhibition of p300 (unknown origin) preincubated for 15 mins followed by addition of substrate [3H] Ac-CoA and measured after 60 mins by liquid scint...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCREB-binding protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580970(CHEMBL5081689)
Affinity DataIC50: 22nMAssay Description:Inhibition of CBP (unknown origin) preincubated for 15 mins followed by addition of substrate [3H] Ac-CoA and measured after 60 mins by liquid scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCREB-binding protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50506366(CHEMBL4524352)
Affinity DataIC50: 28nMAssay Description:Inhibition of CBP (unknown origin) preincubated for 15 mins followed by addition of substrate [3H] Ac-CoA and measured after 60 mins by liquid scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCREB-binding protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580972(CHEMBL5078021)
Affinity DataIC50: 28nMAssay Description:Inhibition of CBP (unknown origin) preincubated for 15 mins followed by addition of substrate [3H] Ac-CoA and measured after 60 mins by liquid scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCREB-binding protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580974(CHEMBL5078353)
Affinity DataIC50: 30nMAssay Description:Inhibition of CBP (unknown origin) preincubated for 15 mins followed by addition of substrate [3H] Ac-CoA and measured after 60 mins by liquid scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCREB-binding protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580973(CHEMBL5084035)
Affinity DataIC50: 41nMAssay Description:Inhibition of CBP (unknown origin) preincubated for 15 mins followed by addition of substrate [3H] Ac-CoA and measured after 60 mins by liquid scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCREB-binding protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580971(CHEMBL5085891)
Affinity DataIC50: 44nMAssay Description:Inhibition of CBP (unknown origin) preincubated for 15 mins followed by addition of substrate [3H] Ac-CoA and measured after 60 mins by liquid scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCREB-binding protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580969(CHEMBL5073432)
Affinity DataIC50: 51nMAssay Description:Inhibition of CBP (unknown origin) preincubated for 15 mins followed by addition of substrate [3H] Ac-CoA and measured after 60 mins by liquid scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCREB-binding protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50467836(CHEMBL4282264)
Affinity DataIC50: 61nMAssay Description:Inhibition of CBP (unknown origin) preincubated for 15 mins followed by addition of substrate [3H] Ac-CoA and measured after 60 mins by liquid scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCREB-binding protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580967(CHEMBL5083262)
Affinity DataIC50: 69nMAssay Description:Inhibition of CBP (unknown origin) preincubated for 15 mins followed by addition of substrate [3H] Ac-CoA and measured after 60 mins by liquid scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580966(CHEMBL5089370)
Affinity DataIC50: 430nMAssay Description:Inhibition of p300 (unknown origin) preincubated for 15 mins followed by addition of substrate [3H] Ac-CoA and measured after 60 mins by liquid scint...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCREB-binding protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580966(CHEMBL5089370)
Affinity DataIC50: 680nMAssay Description:Inhibition of CBP (unknown origin) preincubated for 15 mins followed by addition of substrate [3H] Ac-CoA and measured after 60 mins by liquid scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT2A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580965(CHEMBL5090239)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of GCN5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetN-alpha-acetyltransferase 40(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580965(CHEMBL5090239)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of NatD (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT2B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580965(CHEMBL5090239)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PCAF (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT7(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580965(CHEMBL5090239)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of KAT7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT8(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580965(CHEMBL5090239)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of MOF (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetLysine-specific demethylase 4A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580965(CHEMBL5090239)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of JMJD2A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580965(CHEMBL5090239)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580965(CHEMBL5090239)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580965(CHEMBL5090239)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed