Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50017208
TargetCREB-binding protein(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50600305(CHEMBL5193672)
Affinity DataIC50: 40nMAssay Description:Inhibition of CBP (unknown origin) using biotinylated H4 (1 to 25)-GSGSK peptide as substrate incubated for 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50600302(CHEMBL5193437)
Affinity DataIC50: 56nMAssay Description:Inhibition of N-terminal His tagged human EP300 (1159-1666 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H4 (1 to 25)-GSGSK p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50600297(CHEMBL5174606)
Affinity DataIC50: 130nMAssay Description:Inhibition of N-terminal His tagged human EP300 (1159-1666 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H4 (1 to 25)-GSGSK p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50600297(CHEMBL5174606)
Affinity DataIC50: 130nMAssay Description:Inhibition of N-terminal His tagged human EP300 (1159-1666 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H4 (1 to 25)-GSGSK p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50600296(CHEMBL5177811)
Affinity DataIC50: 140nMAssay Description:Inhibition of N-terminal His tagged human EP300 (1159-1666 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H4 (1 to 25)-GSGSK p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50600305(CHEMBL5193672)
Affinity DataIC50: 150nMAssay Description:Inhibition of N-terminal His tagged human EP300 (1159-1666 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H4 (1 to 25)-GSGSK p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone acetyltransferase p300(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50600300(CHEMBL5184238)
Affinity DataIC50: 170nMAssay Description:Inhibition of N-terminal His tagged human EP300 (1159-1666 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H4 (1 to 25)-GSGSK p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50600301(CHEMBL5178312)
Affinity DataIC50: 180nMAssay Description:Inhibition of N-terminal His tagged human EP300 (1159-1666 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H4 (1 to 25)-GSGSK p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone acetyltransferase p300(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50600298(CHEMBL5187549)
Affinity DataIC50: 190nMAssay Description:Inhibition of N-terminal His tagged human EP300 (1159-1666 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H4 (1 to 25)-GSGSK p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50600299(CHEMBL5191305)
Affinity DataIC50: 220nMAssay Description:Inhibition of N-terminal His tagged human EP300 (1159-1666 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H4 (1 to 25)-GSGSK p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50600304(CHEMBL5207535)
Affinity DataIC50: 260nMAssay Description:Inhibition of N-terminal His tagged human EP300 (1159-1666 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H4 (1 to 25)-GSGSK p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50600297(CHEMBL5174606)
Affinity DataIC50: 380nMAssay Description:Inhibition of EP300 in human LK2 cells assessed as reduction in intracellular histone H3 acetylation at lysine 27 residue incubated for 3 hrs by chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50600297(CHEMBL5174606)
Affinity DataIC50: 380nMAssay Description:Inhibition of EP300 in human LK2 cells assessed as reduction in intracellular histone H3 acetylation at lysine 27 residue incubated for 3 hrs by chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50600300(CHEMBL5184238)
Affinity DataIC50: 420nMAssay Description:Inhibition of EP300 in human LK2 cells assessed as reduction in intracellular histone H3 acetylation at lysine 27 residue incubated for 3 hrs by chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50600305(CHEMBL5193672)
Affinity DataIC50: 450nMAssay Description:Inhibition of EP300 in human LK2 cells assessed as reduction in intracellular histone H3 acetylation at lysine 27 residue incubated for 3 hrs by chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone acetyltransferase p300(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50600302(CHEMBL5193437)
Affinity DataIC50: 460nMAssay Description:Inhibition of EP300 in human LK2 cells assessed as reduction in intracellular histone H3 acetylation at lysine 27 residue incubated for 3 hrs by chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50600296(CHEMBL5177811)
Affinity DataIC50: 610nMAssay Description:Inhibition of EP300 in human LK2 cells assessed as reduction in intracellular histone H3 acetylation at lysine 27 residue incubated for 3 hrs by chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50600295(CHEMBL5209027)
Affinity DataIC50: 610nMAssay Description:Inhibition of N-terminal His tagged human EP300 (1159-1666 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H4 (1 to 25)-GSGSK p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50600301(CHEMBL5178312)
Affinity DataIC50: 690nMAssay Description:Inhibition of EP300 in human LK2 cells assessed as reduction in intracellular histone H3 acetylation at lysine 27 residue incubated for 3 hrs by chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone acetyltransferase p300(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50600303(CHEMBL5180471)
Affinity DataIC50: 910nMAssay Description:Inhibition of N-terminal His tagged human EP300 (1159-1666 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H4 (1 to 25)-GSGSK p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50600298(CHEMBL5187549)
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of EP300 in human LK2 cells assessed as reduction in intracellular histone H3 acetylation at lysine 27 residue incubated for 3 hrs by chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50600304(CHEMBL5207535)
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of EP300 in human LK2 cells assessed as reduction in intracellular histone H3 acetylation at lysine 27 residue incubated for 3 hrs by chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50600303(CHEMBL5180471)
Affinity DataIC50: 1.45E+3nMAssay Description:Inhibition of EP300 in human LK2 cells assessed as reduction in intracellular histone H3 acetylation at lysine 27 residue incubated for 3 hrs by chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50600295(CHEMBL5209027)
Affinity DataIC50: 2.24E+3nMAssay Description:Inhibition of EP300 in human LK2 cells assessed as reduction in intracellular histone H3 acetylation at lysine 27 residue incubated for 3 hrs by chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50600299(CHEMBL5191305)
Affinity DataIC50: 5.02E+3nMAssay Description:Inhibition of EP300 in human LK2 cells assessed as reduction in intracellular histone H3 acetylation at lysine 27 residue incubated for 3 hrs by chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone acetyltransferase KAT7(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50346552(CHEMBL1797936)
Affinity DataIC50: 7.81E+3nMAssay Description:Inhibition of MYST2 (unknown origin) using biotinylated H4 (1 to 25)-GSGSK peptide as substrate incubated for 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone acetyltransferase KAT6B(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50346552(CHEMBL1797936)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of MYST4 (unknown origin) using biotinylated H4 (1 to 25)-GSGSK peptide as substrate incubated for 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50600297(CHEMBL5174606)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of EP300 in human LK2 cells assessed as reduction in intracellular histone H3 acetylation at lysine 27 residue incubated for 3 hrs by chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone acetyltransferase KAT5(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50346552(CHEMBL1797936)
Affinity DataIC50: 3.72E+4nMAssay Description:Inhibition of GST tagged human TIP60 expressed in Sf9 cells using biotinylated H4 (1 to 25)-GSGSK peptide as substrate incubated for 1 hr by AlphaLIS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone acetyltransferase KAT2B(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50346552(CHEMBL1797936)
Affinity DataIC50: 3.89E+4nMAssay Description:Inhibition of GST tagged human PCAF (431 to end residues) expressed in Sf9 cells using biotinylated H3 (1 to 21)-GGK peptide as substrate incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone acetyltransferase KAT2A(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50346552(CHEMBL1797936)
Affinity DataIC50: 4.74E+4nMAssay Description:Inhibition of GST tagged human GCN5 (323 to end residues) expressed in Sf9 cells using biotinylated H3 (1 to 21)-GGK peptide as substrate incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCREB-binding protein(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50346552(CHEMBL1797936)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CBP (unknown origin) using biotinylated H4 (1 to 25)-GSGSK peptide as substrate incubated for 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone acetyltransferase KAT5(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50600305(CHEMBL5193672)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of GST tagged human TIP60 expressed in Sf9 cells using biotinylated H4 (1 to 25)-GSGSK peptide as substrate incubated for 1 hr by AlphaLIS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone acetyltransferase KAT7(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50600305(CHEMBL5193672)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of MYST2 (unknown origin) using biotinylated H4 (1 to 25)-GSGSK peptide as substrate incubated for 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone acetyltransferase KAT6B(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50600305(CHEMBL5193672)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of MYST4 (unknown origin) using biotinylated H4 (1 to 25)-GSGSK peptide as substrate incubated for 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone acetyltransferase KAT2B(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50600305(CHEMBL5193672)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of GST tagged human PCAF (431 to end residues) expressed in Sf9 cells using biotinylated H3 (1 to 21)-GGK peptide as substrate incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone acetyltransferase KAT2A(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50600305(CHEMBL5193672)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of GST tagged human GCN5 (323 to end residues) expressed in Sf9 cells using biotinylated H3 (1 to 21)-GGK peptide as substrate incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed