38 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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Article Title
Organization
2-(3-Methoxyphenyl)quinazoline Derivatives: A New Class of Direct Constitutive Androstane Receptor (CAR) Agonists.
Palacky University In Olomouc
Optimization of ADME Properties for Sulfonamides Leading to the Discovery of a T-Type Calcium Channel Blocker, ABT-639.
Abbvie
Synthesis and biological evaluation of 2,3'-diindolylmethanes as agonists of aryl hydrocarbon receptor.
University of Wisconsin
Bis-aryloxadiazoles as effective activators of the aryl hydrocarbon receptor.
University of Utah
8-Benzamidochromen-4-one-2-carboxylic acids: potent and selective agonists for the orphan G protein-coupled receptor GPR35.
University of Bonn
Three-dimensional quantitative structure-activity relationships from molecular similarity matrices and genetic neural networks. 2. Applications.
Harvard University
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
University of Oxford
Targeting cytochrome P450 enzymes: a new approach in anti-cancer drug development.
University of Maryland
Imidazo[1,5-a]quinoxalines as irreversible BTK inhibitors for the treatment of rheumatoid arthritis.
Pfizer
Improvement in aqueous solubility in small molecule drug discovery programs by disruption of molecular planarity and symmetry.
The University of Tokyo
beta-Naphthoflavone analogs as potent and soluble aryl hydrocarbon receptor agonists: improvement of solubility by disruption of molecular planarity.
The University of Tokyo
Synthesis and biological properties of benzothiazole, benzoxazole, and chromen-4-one analogues of the potent antitumor agent 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (PMX 610, NSC 721648).
Cardiff University
Discovery of 5-((1H-indazol-3-yl) methylene)-2-thioxoimidazolidin-4-one derivatives as a new class of AHR agonists with anti-psoriasis activity in a mouse model.
Sichuan University
Novel Aryl Hydrocarbon Receptor Agonists for Treating Psoriasis.
Smith, Gambrell & Russell
An overview of aryl hydrocarbon receptor ligands in the Last two decades (2002-2022): A medicinal chemistry perspective.
China Pharmaceutical University
2-substituted benzothiazoles as antiproliferative agents: Novel insights on structure-activity relationships.
"G. D'Annunzio" University of Chieti-Pescara
Targeting the Aryl Hydrocarbon Receptor with Microbial Metabolite Mimics Alleviates Experimental Colitis in Mice.
Palack£
Identification of triazolopyridine derivatives as a new class of AhR agonists and evaluation of anti-psoriasis effect in a mouse model.
Sichuan University
The Highly Potent AhR Agonist Picoberin Modulates Hh-Dependent Osteoblast Differentiation.
Max Planck Institute of Molecular Physiology
Structural modification aimed for improving solubility of lead compounds in early phase drug discovery.
Indian Institute of Technology (B.H.U.)
An electrochemical device for the assay of the interaction between a dioxin receptor and its various ligands.
Kyushu University
Targeting the aryl hydrocarbon receptor with a novel set of triarylmethanes.
Universitat De Val£Ncia. Av. Vicente Andr£S Estell£S
Synthesis and biological evaluation of FICZ analogues as agonists of aryl hydrocarbon receptor.
University of Wisconsin-Madison
Development of Chemical Entities Endowed with Potent Fast-Killing Properties against
Glaxosmithkline
Identification of new aryl hydrocarbon receptor (AhR) antagonists using a zebrafish model.
Gwangju Institute of Science and Technology
Targeting Aryl hydrocarbon receptor for next-generation immunotherapies: Selective modulators (SAhRMs) versus rapidly metabolized ligands (RMAhRLs).
University of Perugia
Potential Antiosteoporotic Natural Product Lead Compounds That Inhibit 17β-Hydroxysteroid Dehydrogenase Type 2.
University of Basel
Synthesis and biological evaluation of pyrrole-based chalcones as CYP1 enzyme inhibitors, for possible prevention of cancer and overcoming cisplatin resistance.
De Montfort University
Cytotoxicity and topoisomerase I/II inhibition activity of novel 4-aryl/alkyl-1-(piperidin-4-yl)-carbonylthiosemicarbazides and 4-benzoylthiosemicarbazides.
Medical University
Identification of 2-arylbenzimidazoles as potent human histamine H4 receptor ligands.
Johnson & Johnson Pharmaceutical