Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50017805
TargetAryl hydrocarbon receptor(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50605061(CHEMBL5179114)
Affinity DataEC50:  110nMAssay Description:Agonist activity at AhR (unknown origin) transfected in human AZ-AHR reporter cells derived from human HepG2 cells incubated for 4 hrs by luciferase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50605062(CHEMBL5185943)
Affinity DataEC50:  32nMAssay Description:Agonist activity at AhR (unknown origin) transfected in human AZ-AHR reporter cells derived from human HepG2 cells incubated for 4 hrs by luciferase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50605060(CHEMBL5198290 | US11891386, Compound 004)
Affinity DataEC50:  1.60nMAssay Description:Agonist activity at AhR (unknown origin) transfected in human AZ-AHR reporter cells derived from human HepG2 cells incubated for 4 hrs by luciferase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandPNGBDBM50605060(CHEMBL5198290 | US11891386, Compound 004)
Affinity DataEC50:  1.20E+4nMAssay Description:Agonist activity at human PXR transfected in human LS180 cells cotransfected with luciferase reporter plasmid p2A4-Luc assessed as transcriptional ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Mouse)
Palack£

Curated by ChEMBL
LigandPNGBDBM50506039(CHEMBL1324296 | US11891386, Compound 002)
Affinity DataEC50:  10nMAssay Description:Agonist activity at AhR in mouse Hepa2Dluc cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandPNGBDBM50605060(CHEMBL5198290 | US11891386, Compound 004)
Affinity DataIC50: 3.21E+4nMAssay Description:Displacement of fluorescence labeled ligand from human PXR ligand binding domain by Lanthascreen TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Mouse)
Palack£

Curated by ChEMBL
LigandPNGBDBM50506039(CHEMBL1324296 | US11891386, Compound 002)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]TCDD from mouse AhR expressed in mouse Hepa1c1c7 cells cytosol incubated for 2 hrs by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Mouse)
Palack£

Curated by ChEMBL
LigandPNGBDBM50605060(CHEMBL5198290 | US11891386, Compound 004)
Affinity DataKi:  88nMAssay Description:Displacement of [3H]TCDD from mouse AhR expressed in mouse Hepa1c1c7 cells cytosol incubated for 2 hrs by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Mouse)
Palack£

Curated by ChEMBL
LigandPNGBDBM50605061(CHEMBL5179114)
Affinity DataKi:  800nMAssay Description:Displacement of [3H]TCDD from mouse AhR expressed in mouse Hepa1c1c7 cells cytosol incubated for 2 hrs by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed