19 articles for thisTarget
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Discovery of a novel dual-target inhibitor of CDK12 and PARP1 that induces synthetic lethality for treatment of triple-negative breast cancer.

Southwest Jiaotong University
Research progress of VEGFR small molecule inhibitors in ocular neovascular diseases.

Southwest Jiaotong University
Targeting protein kinases for the treatment of Alzheimer's disease: Recent progress and future perspectives.

Southwest Jiaotong University
Unleashing the Potential of Camptothecin: Exploring Innovative Strategies for Structural Modification and Therapeutic Advancements.

Southwest Jiaotong University
Targeting VPS34 in autophagy: An update on pharmacological small-molecule compounds.

Southwest Jiaotong University
Deciphering the multifunctional role of dual leucine zipper kinase (DLK) and its therapeutic potential in disease.

Southwest Jiaotong University
Targeting Death-Associated Protein Kinases for Treatment of Human Diseases: Recent Advances and Future Directions.

Southwest Jiaotong University
Palladium-Catalyzed Synthesis, Acetylcholinesterase Inhibition, and Neuroprotective Activities of

Southwest Jiaotong University
Recent advances of dual FGFR inhibitors as a novel therapy for cancer.

Southwest Jiaotong University
Targeting Extracellular Signal-Regulated Protein Kinase 1/2 (ERK1/2) in Cancer: An Update on Pharmacological Small-Molecule Inhibitors.

Southwest Jiaotong University
Inhibiting Sodium Taurocholate Cotransporting Polypeptide in HBV-Related Diseases: From Biological Function to Therapeutic Potential.

Southwest Jiaotong University
Identification of a selective BRD4 PROTAC with potent antiproliferative effects in AR-positive prostate cancer based on a dual BET/PLK1 inhibitor.

Southwest Jiaotong University
NAE modulators: A potential therapy for gastric carcinoma.

Southwest Jiaotong University
Pd-Catalyzed Direct Diversification of Natural Anti-Alzheimer's Disease Drug: Synthesis and Biological Evaluation of

Southwest Jiaotong University
Discovery of a novel small-molecule inhibitor of Fam20C that induces apoptosis and inhibits migration in triple negative breast cancer.

Southwest Jiaotong University
Design, synthesis and structure-activity relationship study of piperazinone-containing thieno[3,2-d]pyrimidine derivatives as new PI3Kδ inhibitors.

Southwest Jiaotong University
Design, synthesis, and biological evaluation of 4,5-dihydro-[1,2,4]triazolo[4,3-f]pteridine derivatives as novel dual-PLK1/BRD4 inhibitors.

Southwest Jiaotong University
Design, synthesis and biological evaluation of benzamide derivatives as novel NTCP inhibitors that induce apoptosis in HepG2 cells.

Southwest Jiaotong University
Natural products as important tyrosine kinase inhibitors.

Southwest Jiaotong University