Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50020407
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM527983(US11179399, Example 25_2)
Affinity DataKd:  1nMAssay Description:Binding affinity to VPS34 (unknown origin) assessed as dissociation constant by KINOMEscan analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50610495(CHEMBL5286775)
Affinity DataKd:  0.530nMAssay Description:Binding affinity to VPS34 (unknown origin) assessed as dissociation constant by KINOMEscan analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50121212(CHEMBL3622372)
Affinity DataIC50: 1.20nMAssay Description:Competitive inhibition of recombinant human VPS34 in presence of ATP by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandPNGBDBM50503134(CHEMBL4447963)
Affinity DataIC50: 6nMAssay Description:Competitive inhibition of P13Kdelta (unknown origin) using PIP2:PS as substrate preincubated for 1 hr followed by substrate addition for 1 hr by ADP-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50629710(CHEMBL5436994)
Affinity DataIC50: 7.60nMAssay Description:Competitive inhibition of VPS34 (unknown origin) incubated for 15 mins in presence of ATP by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50156294(CHEMBL3781415)
Affinity DataIC50: 18nMAssay Description:Inhibition of Vps34 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50503134(CHEMBL4447963)
Affinity DataIC50: 19nMAssay Description:Competitive inhibition of Vps34 (unknown origin) using PI:PS as substrate preincubated for 1 hr followed by substrate addition for 1 hr by ADP-Glo as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50197067(CHEMBL3913746)
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human Vps34-Vps15 complex expressed in insect cells assessed as reduction in PtdIns phosphorylation in presence of gamma32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50121212(CHEMBL3622372)
Affinity DataIC50: 38nMAssay Description:Competitive inhibition of VPS34 (unknown origin) incubated for 15 mins in presence of ATP by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed