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51 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Phloroglucinol Derivatives with Protein Tyrosine Phosphatase 1B Inhibitory Activities from Eugenia jambolana Seeds.EBI
Northeastern University
Probing the carboxyester side chain in controlled deactivation (-)-d(8)-tetrahydrocannabinols.EBI
Northeastern University
Novel tail and head group prostamide probes.EBI
Northeastern University
Repurposing human PDE4 inhibitors for neglected tropical diseases: design, synthesis and evaluation of cilomilast analogues as Trypanosoma brucei PDEB1 inhibitors.EBI
Northeastern University
Synthesis and Structure-Activity Relationship Study of 5a-Carbasugar Analogues of SL0101.EBI
Northeastern University
Establishment of a structure-activity relationship of 1H-imidazo[4,5-c]quinoline-based kinase inhibitor NVP-BEZ235 as a lead for African sleeping sickness.EBI
Northeastern University
C-ring cannabinoid lactones: a novel cannabinergic chemotype.EBI
Northeastern University
Expeditious synthesis, enantiomeric resolution, and enantiomer functional characterization of (4-(4-bromophenyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide (4BP-TQS): an allosteric agonist-positive allosteric modulator of α7 nicotinic acetylcholine receptors.EBI
Northeastern University
Synthesis and assessment of catechol diether compounds as inhibitors of trypanosomal phosphodiesterase B1 (TbrPDEB1).EBI
Northeastern University
Novel adamantyl cannabinoids as CB1 receptor probes.EBI
Northeastern University
Sulfonyl fluoride inhibitors of fatty acid amide hydrolase.EBI
Northeastern University
Assay and inhibition of diacylglycerol lipase activity.EBI
Northeastern University
Synthesis and evaluation of 11ß-(4-substituted phenyl) estradiol analogs: transition from estrogen receptor agonists to antagonists.EBI
Northeastern University
Potent cannabinergic indole analogues as radioiodinatable brain imaging agents for the CB1 cannabinoid receptor.EBI
Northeastern University
(+/-)-3-allyl-7-halo-8-hydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines as selective high affinity D1 dopamine receptor antagonists: synthesis and structure-activity relationship.EBI
Northeastern University
(+/-)-3-Allyl-6-bromo-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3- benzazepin, a new high-affinity D1 dopamine receptor ligand: synthesis and structure-activity relationship.EBI
Northeastern University
R and S enantiomers of 11-hydroxy- and 10,11-dihydroxy-N-allylnoraporphine: synthesis and affinity for dopamine receptors in rat brain tissue.EBI
Northeastern University
Synthesis and structural requirements of N-substituted norapomorphines for affinity and activity at dopamine D-1, D-2, and agonist receptor sites in rat brain.EBI
Northeastern University
A photoaffinity label for the D-1 dopamine receptor, (RS)-7-[125I]Iodo-8-hydroxy-3-methyl-1-(4'-azidophenyl)-2,3,4,5- tetrahydro-1H-3-benzazepine, selectively identifies the ligand binding subunits of the receptor.EBI
Northeastern University
Conformationally constrained analogs of BAY 59-3074 as novel cannabinoid receptor ligands.EBI
Northeastern University
Novel 1',1'-chain substituted hexahydrocannabinols: 9ß-hydroxy-3-(1-hexyl-cyclobut-1-yl)-hexahydrocannabinol (AM2389) a highly potent cannabinoid receptor 1 (CB1) agonist.EBI
Northeastern University
Bornyl- and isobornyl-Delta8-tetrahydrocannabinols: a novel class of cannabinergic ligands.EBI
Northeastern University
Development of novel tail-modified anandamide analogs.EBI
Northeastern University
Cannabilactones: a novel class of CB2 selective agonists with peripheral analgesic activity.EBI
Northeastern University
Conformationally constrained analogues of 2-arachidonoylglycerol.EBI
Northeastern University
Adamantyl cannabinoids: a novel class of cannabinergic ligands.EBI
Northeastern University
Design, synthesis, and pharmacological profiling of cannabinoid 1 receptor allosteric modulators: Preclinical efficacy of C2-group GAT211 congeners for reducing intraocular pressure.EBI
Northeastern University
Discovery of Anti-TNBC Agents Targeting PTP1B: Total Synthesis, Structure-Activity Relationship, EBI
Northeastern University
Design and Structure-Activity Relationships of Isothiocyanates as Potent and Selective EBI
Northeastern University
Focused structure-activity relationship profiling around the 2-phenylindole scaffold of a cannabinoid type-1 receptor agonist-positive allosteric modulator: site-III aromatic-ring congeners with enhanced activity and solubility.EBI
Northeastern University
Synthesis of novel 5-substituted-2-aminotetralin analogs: 5-HTEBI
Northeastern University
Design and synthesis of cyanamides as potent and selective N-acylethanolamine acid amidase inhibitors.EBI
Northeastern University
Novel C-Ring-Hydroxy-Substituted Controlled Deactivation Cannabinergic Analogues.EBI
Northeastern University
Application of Fluorine- and Nitrogen-Walk Approaches: Defining the Structural and Functional Diversity of 2-Phenylindole Class of Cannabinoid 1 Receptor Positive Allosteric Modulators.EBI
Northeastern University
Piperidine and piperazine inhibitors of fatty acid amide hydrolase targeting excitotoxic pathology.EBI
Northeastern University
Selectivity and Physicochemical Optimization of Repurposed Pyrazolo[1,5-EBI
Northeastern University
Enantioselectivity of cocaine recognition sites: binding of (1S)- and (1R)-2 beta-carbomethoxy-3 beta-(4-iodophenyl)tropane (beta-CIT) to monoamine transporters.EBI
Northeastern University
4,4'-Unsymmetrically substituted 3,3'-biphenyl alpha helical proteomimetics as potential coactivator binding inhibitors.EBI
Northeastern University
Controlled-deactivation cannabinergic ligands.EBI
Northeastern University
High affinity electrophilic and photoactivatable covalent endocannabinoid probes for the CB1 receptor.EBI
Northeastern University
Stereochemical Structure Activity Relationship Studies (S-SAR) of Tetrahydrolipstatin.EBI
Northeastern University
Oximes short-acting CB1 receptor agonists.EBI
Northeastern University
Synthesis and dopamine agonist and antagonist effects of (R)-(-)- and (S)-(+)-11-hydroxy-N-n-propylnoraporphine.EBI
Northeastern University
( R)- N-(1-Methyl-2-hydroxyethyl)-13-( S)-methyl-arachidonamide (AMG315): A Novel Chiral Potent Endocannabinoid Ligand with Stability to Metabolizing Enzymes.EBI
Northeastern University
2-Haloaporphines as potent dopamine agonists.EBI
Northeastern University
Synthesis and dopamine receptor affinities of enantiomers of 2-substituted apomorphines and their N-n-propyl analogues.EBI
Northeastern University
STK19 inhibitors for treatment of cancerBDB
Trustees of Boston University
TRIAZOLONE COMPOUNDS AND USES THEREOFBDB
Tempest Therapeutics
Isoxazole carboxamides as irreversible SMYD inhibitorsBDB
Epizyme
In vitro inhibition effect and structure-activity relationships of some saccharin derivatives on erythrocyte carbonic anhydrase I and II.BDB
Sakarya University
Subtype selectivity of peptide analogs for all five cloned human somatostatin receptors (hsstr 1-5).BDB
Mcgill University