51 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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Phloroglucinol Derivatives with Protein Tyrosine Phosphatase 1B Inhibitory Activities from Eugenia jambolana Seeds.

Northeastern University
Probing the carboxyester side chain in controlled deactivation (-)-d(8)-tetrahydrocannabinols.

Northeastern University
Novel tail and head group prostamide probes.

Northeastern University
Repurposing human PDE4 inhibitors for neglected tropical diseases: design, synthesis and evaluation of cilomilast analogues as Trypanosoma brucei PDEB1 inhibitors.

Northeastern University
Synthesis and Structure-Activity Relationship Study of 5a-Carbasugar Analogues of SL0101.

Northeastern University
Establishment of a structure-activity relationship of 1H-imidazo[4,5-c]quinoline-based kinase inhibitor NVP-BEZ235 as a lead for African sleeping sickness.

Northeastern University
C-ring cannabinoid lactones: a novel cannabinergic chemotype.

Northeastern University
Expeditious synthesis, enantiomeric resolution, and enantiomer functional characterization of (4-(4-bromophenyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide (4BP-TQS): an allosteric agonist-positive allosteric modulator of α7 nicotinic acetylcholine receptors.

Northeastern University
Synthesis and assessment of catechol diether compounds as inhibitors of trypanosomal phosphodiesterase B1 (TbrPDEB1).

Northeastern University
Novel adamantyl cannabinoids as CB1 receptor probes.

Northeastern University
Sulfonyl fluoride inhibitors of fatty acid amide hydrolase.

Northeastern University
Assay and inhibition of diacylglycerol lipase activity.

Northeastern University
Synthesis and evaluation of 11ß-(4-substituted phenyl) estradiol analogs: transition from estrogen receptor agonists to antagonists.

Northeastern University
Potent cannabinergic indole analogues as radioiodinatable brain imaging agents for the CB1 cannabinoid receptor.

Northeastern University
(+/-)-3-allyl-7-halo-8-hydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines as selective high affinity D1 dopamine receptor antagonists: synthesis and structure-activity relationship.

Northeastern University
(+/-)-3-Allyl-6-bromo-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3- benzazepin, a new high-affinity D1 dopamine receptor ligand: synthesis and structure-activity relationship.

Northeastern University
R and S enantiomers of 11-hydroxy- and 10,11-dihydroxy-N-allylnoraporphine: synthesis and affinity for dopamine receptors in rat brain tissue.

Northeastern University
Synthesis and structural requirements of N-substituted norapomorphines for affinity and activity at dopamine D-1, D-2, and agonist receptor sites in rat brain.

Northeastern University
A photoaffinity label for the D-1 dopamine receptor, (RS)-7-[125I]Iodo-8-hydroxy-3-methyl-1-(4'-azidophenyl)-2,3,4,5- tetrahydro-1H-3-benzazepine, selectively identifies the ligand binding subunits of the receptor.

Northeastern University
Conformationally constrained analogs of BAY 59-3074 as novel cannabinoid receptor ligands.

Northeastern University
Novel 1',1'-chain substituted hexahydrocannabinols: 9ß-hydroxy-3-(1-hexyl-cyclobut-1-yl)-hexahydrocannabinol (AM2389) a highly potent cannabinoid receptor 1 (CB1) agonist.

Northeastern University
Bornyl- and isobornyl-Delta8-tetrahydrocannabinols: a novel class of cannabinergic ligands.

Northeastern University
Development of novel tail-modified anandamide analogs.

Northeastern University
Cannabilactones: a novel class of CB2 selective agonists with peripheral analgesic activity.

Northeastern University
Conformationally constrained analogues of 2-arachidonoylglycerol.

Northeastern University
Adamantyl cannabinoids: a novel class of cannabinergic ligands.

Northeastern University
Design, synthesis, and pharmacological profiling of cannabinoid 1 receptor allosteric modulators: Preclinical efficacy of C2-group GAT211 congeners for reducing intraocular pressure.

Northeastern University
Discovery of Anti-TNBC Agents Targeting PTP1B: Total Synthesis, Structure-Activity Relationship,

Northeastern University
Design and Structure-Activity Relationships of Isothiocyanates as Potent and Selective

Northeastern University
Focused structure-activity relationship profiling around the 2-phenylindole scaffold of a cannabinoid type-1 receptor agonist-positive allosteric modulator: site-III aromatic-ring congeners with enhanced activity and solubility.

Northeastern University
Synthesis of novel 5-substituted-2-aminotetralin analogs: 5-HT

Northeastern University
Design and synthesis of cyanamides as potent and selective N-acylethanolamine acid amidase inhibitors.

Northeastern University
Novel C-Ring-Hydroxy-Substituted Controlled Deactivation Cannabinergic Analogues.

Northeastern University
Application of Fluorine- and Nitrogen-Walk Approaches: Defining the Structural and Functional Diversity of 2-Phenylindole Class of Cannabinoid 1 Receptor Positive Allosteric Modulators.

Northeastern University
Piperidine and piperazine inhibitors of fatty acid amide hydrolase targeting excitotoxic pathology.

Northeastern University
Selectivity and Physicochemical Optimization of Repurposed Pyrazolo[1,5-

Northeastern University
Enantioselectivity of cocaine recognition sites: binding of (1S)- and (1R)-2 beta-carbomethoxy-3 beta-(4-iodophenyl)tropane (beta-CIT) to monoamine transporters.

Northeastern University
4,4'-Unsymmetrically substituted 3,3'-biphenyl alpha helical proteomimetics as potential coactivator binding inhibitors.

Northeastern University
Controlled-deactivation cannabinergic ligands.

Northeastern University
High affinity electrophilic and photoactivatable covalent endocannabinoid probes for the CB1 receptor.

Northeastern University
Stereochemical Structure Activity Relationship Studies (S-SAR) of Tetrahydrolipstatin.

Northeastern University
Oximes short-acting CB1 receptor agonists.

Northeastern University
Synthesis and dopamine agonist and antagonist effects of (R)-(-)- and (S)-(+)-11-hydroxy-N-n-propylnoraporphine.

Northeastern University
( R)- N-(1-Methyl-2-hydroxyethyl)-13-( S)-methyl-arachidonamide (AMG315): A Novel Chiral Potent Endocannabinoid Ligand with Stability to Metabolizing Enzymes.

Northeastern University
2-Haloaporphines as potent dopamine agonists.

Northeastern University
Synthesis and dopamine receptor affinities of enantiomers of 2-substituted apomorphines and their N-n-propyl analogues.

Northeastern University
STK19 inhibitors for treatment of cancer

Trustees of Boston University
TRIAZOLONE COMPOUNDS AND USES THEREOF

Tempest Therapeutics
Isoxazole carboxamides as irreversible SMYD inhibitors

Epizyme
In vitro inhibition effect and structure-activity relationships of some saccharin derivatives on erythrocyte carbonic anhydrase I and II.

Sakarya University
Subtype selectivity of peptide analogs for all five cloned human somatostatin receptors (hsstr 1-5).

Mcgill University