16 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Optimization of spirocyclic proline tryptophan hydroxylase-1 inhibitors.
Karos Pharmaceuticals
Discovery of spirocyclic proline tryptophan hydroxylase-1 inhibitors.
Karos Pharmaceuticals
Tryptophan hydroxylase 1 (Tph-1)-targeted bone anabolic agents for osteoporosis.
Nanjing University
Substituted 3-(4-(1,3,5-triazin-2-yl)-phenyl)-2-aminopropanoic acids as novel tryptophan hydroxylase inhibitors.
Lexicon Pharmaceuticals
Modulation of peripheral serotonin levels by novel tryptophan hydroxylase inhibitors for the potential treatment of functional gastrointestinal disorders.
Lexicon Pharmaceuticals
Structure-Based Design of Xanthine-Imidazopyridines and -Imidazothiazoles as Highly Potent and In Vivo Efficacious Tryptophan Hydroxylase Inhibitors.
Leibniz-Fmp
Synthesis and biological evaluation of xanthine derivatives with phenacyl group as tryptophan hydroxylase 1 (TPH1) inhibitors for obesity and fatty liver disease.
Gwangju Institute of Science and Technology
A decade of approved first-in-class small molecule orphan drugs: Achievements, challenges and perspectives.
China Pharmaceutical University
Structure-Based Design of Xanthine-Benzimidazole Derivatives as Novel and Potent Tryptophan Hydroxylase Inhibitors.
Leibniz-Forschungsinstitut F�R Molekulare Pharmakologie (Fmp)
Peripheral Selective Oxadiazolylphenyl Alanine Derivatives as Tryptophan Hydroxylase 1 Inhibitors for Obesity and Fatty Liver Disease.
Gwangju Institute of Science and Technology
(S)-5-ethynyl-anabasine, derivatives thereof, and related compositions and methods of making and using
Iowa State University Research Foundation