Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50044498
TargetTryptophan 5-hydroxylase 1(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50019142(CHEMBL3288777)
Affinity DataKd:  6.82E+3nMAssay Description:Binding affinity to TPH-1 (unknown origin) by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Rat)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50019143(CHEMBL511275 | US10683309, Example LP533401)
Affinity DataIC50: 400nMAssay Description:Inhibition of TPH-1-mediated serotonin biosynthesis in rat RBL2H3 cells after 48 hrs by RP-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Rat)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50019142(CHEMBL3288777)
Affinity DataIC50: 6.22E+3nMAssay Description:Inhibition of TPH-1-mediated serotonin biosynthesis in rat RBL2H3 cells after 48 hrs by RP-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 2(Rat)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50019142(CHEMBL3288777)
Affinity DataIC50: 4.55E+4nMAssay Description:Inhibition of TPH-2-mediated serotonin biosynthesis in rat PC12 cells after 48 hrs by RP-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed