Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50030758
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50300929((S)-2-amino-3-(4-(4-amino-6-(biphenyl-2-ylmethylam...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50300932((S)-2-amino-3-(4-(4-amino-6-((4'-methylbiphenyl-4-...)
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50300935((S)-3-{4-[4-(1-Adamantan-1-yl-ethylamino)-6-amino-...)
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243613((S)-2-amino-3-(4-(4-amino-6-(naphthalen-2-ylmethyl...)
Affinity DataIC50: 24nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50300934((2S)-2-amino-3-(4-(4-amino-6-(1-(biphenyl-4-yl)eth...)
Affinity DataIC50: 24nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243020((S)-2-amino-3-(4-(4-amino-6-((R)-1-(naphthalen-2-y...)
Affinity DataIC50: 26nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50300930((S)-2-amino-3-(4-(4-amino-6-(biphenyl-3-ylmethylam...)
Affinity DataIC50: 38nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50300936((S)-2-amino-3-(4-(4-amino-6-((S)-1-(naphthalen-2-y...)
Affinity DataIC50: 44nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50300940((S)-2-amino-3-(4-(4-amino-6-(methyl((R)-1-(naphtha...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50300937((S)-2-amino-3-(4-(4-amino-6-(2-(naphthalen-2-yl)pr...)
Affinity DataIC50: 55nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50300928((S)-2-amino-3-(4-(4-amino-6-(biphenyl-4-ylmethylam...)
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50300925((S)-2-amino-3-(4-(4-amino-6-(3,4-dimethylbenzylami...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50300926((S)-2-amino-3-(4-(4-amino-6-(4-(trifluoromethyl)be...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50300924((S)-2-amino-3-(4-(4-amino-6-(cyclohexylmethylamino...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50300942((2S)-2-amino-3-(4-(4-amino-6-(3-methyl-1-(naphthal...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50300931((S)-2-amino-3-(4-(4-amino-6-(4-phenoxybenzylamino)...)
Affinity DataIC50: 150nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50300941((2S)-2-amino-3-(4-(4-amino-6-(1-(naphthalen-2-yl)p...)
Affinity DataIC50: 150nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50300933((S)-2-amino-3-(4-(4-amino-6-((4'-(trifluoromethyl)...)
Affinity DataIC50: 160nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50300946((2S)-2-amino-3-(4-(4-(1-(naphthalen-2-yl)ethylamin...)
Affinity DataIC50: 190nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50300943((2S)-2-amino-3-(4-(4-amino-6-(2-methyl-1-(naphthal...)
Affinity DataIC50: 250nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50300938((2S)-2-amino-3-(4-(4-amino-6-(2,2,2-trifluoro-1-(n...)
Affinity DataIC50: 320nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50300939((2S)-2-amino-3-(4-(4-amino-6-(2,2,2-trifluoro-1-(n...)
Affinity DataIC50: 330nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50300927((S)-2-amino-3-(4-(4-amino-6-(benzylamino)-1,3,5-tr...)
Affinity DataIC50: 500nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50300945((S)-2-amino-3-(4-(4-(methylamino)-6-((R)-1-(naphth...)
Affinity DataIC50: 610nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50300944((S)-2-amino-3-(4-(4-morpholino-6-(naphthalen-2-ylm...)
Affinity DataIC50: 1.56E+4nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed