31 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Discovery of Highly Potent and Selective Small-Molecule Reversible Factor D Inhibitors Demonstrating Alternative Complement Pathway Inhibition in Vivo.
Novartis Pharma
Structure-Based Library Design and Fragment Screening for the Identification of Reversible Complement Factor D Protease Inhibitors.
Novartis Institutes For Biomedical Research
Discovery of a new isomannide-based peptidomimetic synthetized by Ugi multicomponent reaction as human tissue kallikrein 1 inhibitor.
Universidade Federal Fluminense
Isocoumarins, miraculous natural products blessed with diverse pharmacological activities.
Quaid-I-Azam University
The natural flavone fukugetin as a mixed-type inhibitor for human tissue kallikreins.
Campus
Improving the Selectivity of Engineered Protease Inhibitors: Optimizing the P2 Prime Residue Using a Versatile Cyclic Peptide Library.
Queensland University of Technology
Pyrido-imidazodiazepinones as a new class of reversible inhibitors of human kallikrein 7.
University of Montpellier
Isomannide-based peptidomimetics as inhibitors for human tissue kallikreins 5 and 7.
Universidade Federal Do Abc
Identification by in silico and in vitro screenings of small organic molecules acting as reversible inhibitors of kallikreins.
Pierre and Marie Curie University
1,2,4-Triazole derivatives as transient inactivators of kallikreins involved in skin diseases.
Pierre and Marie Curie University
Isomannide derivatives as new class of inhibitors for human kallikrein 7.
Universidade Federal Do Tri£Ngulo Mineiro
Biological evaluation and docking studies of natural isocoumarins as inhibitors for human kallikrein 5 and 7.
Universidade Federal Do Tri£Ngulo Mineiro
Ahp-Cyclodepsipeptides as tunable inhibitors of human neutrophil elastase and kallikrein 7: Total synthesis of tutuilamide A, serine protease selectivity profile and comparison with lyngbyastatin 7.
University of Florida
Phage Display Selected Cyclic Peptide Inhibitors of Kallikrein-Related Peptidases 5 and 7 and Their
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)
Kallikrein 5 inhibitors identified through structure based drug design in search for a treatment for Netherton Syndrome.
Glaxosmithkline R&D
Design and development of a series of borocycles as selective, covalent kallikrein 5 inhibitors.
Glaxosmithkline
Structure guided drug design to develop kallikrein 5 inhibitors to treat Netherton syndrome.
Glaxosmithkline R&D
Binding Loop Substitutions in the Cyclic Peptide SFTI-1 Generate Potent and Selective Chymase Inhibitors.
The University of Queensland
Discovery and structure-activity relationship of imidazolinylindole derivatives as kallikrein 7 inhibitors.
Asubio Pharma
Amino Acid Scanning at P5' within the Bowman-Birk Inhibitory Loop Reveals Specificity Trends for Diverse Serine Proteases.
The University of Queensland
Potent, Selective, and Cell-Penetrating Inhibitors of Kallikrein-Related Peptidase 4 Based on the Cyclic Peptide MCoTI-II.
The University of Queensland
3-Acyltetramic acids as a novel class of inhibitors for human kallikreins 5 and 7.
Universidade Federal Fluminense
Structure-based drug design of 1,3,6-trisubstituted 1,4-diazepan-7-ones as selective human kallikrein 7 inhibitors.
Asubio Pharma
Depsipeptides Featuring a Neutral P1 Are Potent Inhibitors of Kallikrein-Related Peptidase 6 with On-Target Cellular Activity.
German Cancer Research Center (Dkfz)
Discovery and structure-activity relationship study of 1,3,6-trisubstituted 1,4-diazepane-7-ones as novel human kallikrein 7 inhibitors.
Asubio Pharma
Discovery, Synthesis, Pharmacological Profiling, and Biological Characterization of Brintonamides A-E, Novel Dual Protease and GPCR Modulators from a Marine Cyanobacterium.
University of Florida
Structure-based drug design to overcome species differences in kallikrein 7 inhibition of 1,3,6-trisubstituted 1,4-diazepan-7-ones.
Asubio Pharma
Design of Potent and Selective Cathepsin G Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold.
The University of Queensland
Pyrrolo[2,1-F[1,2,4]triazine compounds, preparation methods and applications thereof
Shanghai Institute of Material Medica, Chinese Academy of Sciences