Compile Data Set for Download or QSAR
Report error Found 63 Enz. Inhib. hit(s) with all data for entry = 50008519
TargetChymase(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520051(CHEMBL4592765)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human chymase expressed in Pichia pastoris X-33 cells assessed as decrease in angiotensin 1 cleavage to angiotensin 2 incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetChymase(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520049(CHEMBL4560112)
Affinity DataIC50: 33nMAssay Description:Inhibition of recombinant human chymase expressed in Pichia pastoris X-33 cells assessed as decrease in angiotensin 1 cleavage to angiotensin 2 incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetChymase(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520052(CHEMBL4554739)
Affinity DataIC50: 290nMAssay Description:Inhibition of recombinant human chymase expressed in Pichia pastoris X-33 cells assessed as decrease in angiotensin 1 cleavage to angiotensin 2 incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetChymase(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50124947(CHEMBL453539)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human chymase expressed in Pichia pastoris X-33 cells using NleTDY-pNA as substrate assessed as cleavage of pNA at pH 7.2 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetChymase(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520054(CHEMBL4471031)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human chymase expressed in Pichia pastoris X-33 cells using NleTDY-pNA as substrate assessed as cleavage of pNA at pH 7.2 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetChymase(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520067(CHEMBL4546815)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human chymase expressed in Pichia pastoris X-33 cells using NleTDY-pNA as substrate assessed as cleavage of pNA at pH 7.2 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetProthrombin(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520060(CHEMBL4465306)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human thrombin using Boc-VPR-MCA as substrate at pH 8 and 298 K measured every 60 secs for 600 secsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520061(CHEMBL4556207)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human neutrophil elastase using MeOSuc-AAPV-MCA as substrate at pH 7.2 and 298 K measured every 60 secs for 600 secsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520052(CHEMBL4554739)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human neutrophil elastase using MeOSuc-AAPV-MCA as substrate at pH 7.2 and 298 K measured every 60 secs for 600 secsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetKallikrein-7(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520061(CHEMBL4556207)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human KLK7 expressed in Pichia pastoris X-33 using KHLY-pNA as substrate at pH 8 and 298 K measured every 60 secs for 600 s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetKallikrein-7(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520049(CHEMBL4560112)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human KLK7 expressed in Pichia pastoris X-33 using KHLY-pNA as substrate at pH 8 and 298 K measured every 60 secs for 600 s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetProthrombin(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520061(CHEMBL4556207)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human thrombin using Boc-VPR-MCA as substrate at pH 8 and 298 K measured every 60 secs for 600 secsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520049(CHEMBL4560112)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human coagulation factor 12a using Ac-QRFR-pNA as substrate at pH 8 and 298 K measured every 60 secs for 600 secsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520061(CHEMBL4556207)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human coagulation factor 12a using Ac-QRFR-pNA as substrate at pH 8 and 298 K measured every 60 secs for 600 secsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetChymase(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520062(CHEMBL4472737)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human chymase expressed in Pichia pastoris X-33 cells using NleTDY-pNA as substrate assessed as cleavage of pNA at pH 7.2 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetChymotrypsinogen B2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520052(CHEMBL4554739)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human chymotrypsin using Suc-AAPF-MCA as substrate at pH 8 and 298 K measured every 60 secs for 600 secsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520049(CHEMBL4560112)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human neutrophil elastase using MeOSuc-AAPV-MCA as substrate at pH 7.2 and 298 K measured every 60 secs for 600 secsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520060(CHEMBL4465306)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human coagulation factor 12a using Ac-QRFR-pNA as substrate at pH 8 and 298 K measured every 60 secs for 600 secsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetKallikrein-7(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520060(CHEMBL4465306)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human KLK7 expressed in Pichia pastoris X-33 using KHLY-pNA as substrate at pH 8 and 298 K measured every 60 secs for 600 s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520060(CHEMBL4465306)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human neutrophil elastase using MeOSuc-AAPV-MCA as substrate at pH 7.2 and 298 K measured every 60 secs for 600 secsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetProthrombin(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520052(CHEMBL4554739)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human thrombin using Boc-VPR-MCA as substrate at pH 8 and 298 K measured every 60 secs for 600 secsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520052(CHEMBL4554739)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human coagulation factor 12a using Ac-QRFR-pNA as substrate at pH 8 and 298 K measured every 60 secs for 600 secsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetKallikrein-7(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520052(CHEMBL4554739)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human KLK7 expressed in Pichia pastoris X-33 using KHLY-pNA as substrate at pH 8 and 298 K measured every 60 secs for 600 s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetProthrombin(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520049(CHEMBL4560112)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human thrombin using Boc-VPR-MCA as substrate at pH 8 and 298 K measured every 60 secs for 600 secsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCathepsin G(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520048(CHEMBL4450993)
Affinity DataKi: <0.100nMAssay Description:Inhibition of human cathepsin G using Suc-AAPF-MCA as substrate at pH 7.2 and 298 K measured every 60 secs for 600 secsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520068(CHEMBL4447828)
Affinity DataKi: <0.100nMAssay Description:Inhibition of bovine beta-trypsin using L-BAPNA as substrate preincubated for 5 mins followed by substrate addition measured after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetChymase(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520051(CHEMBL4592765)
Affinity DataKi:  0.220nMAssay Description:Inhibition of recombinant human chymase expressed in Pichia pastoris X-33 cells using NleTDY-pNA as substrate assessed as cleavage of pNA at pH 7.2 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCathepsin G(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520051(CHEMBL4592765)
Affinity DataKi:  0.260nMAssay Description:Inhibition of human cathepsin G using Suc-AAPF-MCA as substrate at pH 7.2 and 298 K measured every 60 secs for 600 secsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetChymotrypsinogen B2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520048(CHEMBL4450993)
Affinity DataKi:  0.420nMAssay Description:Inhibition of human chymotrypsin using Suc-AAPF-MCA as substrate at pH 8 and 298 K measured every 60 secs for 600 secsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetChymotrypsinogen B2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520063(CHEMBL4586444)
Affinity DataKi:  0.880nMAssay Description:Inhibition of human chymotrypsin using Suc-AAPF-MCA as substrate at pH 8 and 298 K measured every 60 secs for 600 secsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetChymotrypsinogen B2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520058(CHEMBL4469390)
Affinity DataKi:  1.5nMAssay Description:Inhibition of human chymotrypsin using Suc-AAPF-MCA as substrate at pH 8 and 298 K measured every 60 secs for 600 secsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetChymase(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520048(CHEMBL4450993)
Affinity DataKi:  1.70nMAssay Description:Inhibition of recombinant human chymase expressed in Pichia pastoris X-33 cells using NleTDY-pNA as substrate assessed as cleavage of pNA at pH 7.2 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetChymase(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520049(CHEMBL4560112)
Affinity DataKi:  1.80nMAssay Description:Inhibition of recombinant human chymase expressed in Pichia pastoris X-33 cells using NleTDY-pNA as substrate assessed as cleavage of pNA at pH 7.2 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetChymase(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520060(CHEMBL4465306)
Affinity DataKi:  2.20nMAssay Description:Inhibition of recombinant human chymase expressed in Pichia pastoris X-33 cells using NleTDY-pNA as substrate assessed as cleavage of pNA at pH 7.2 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetChymase(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520063(CHEMBL4586444)
Affinity DataKi:  5.70nMAssay Description:Inhibition of recombinant human chymase expressed in Pichia pastoris X-33 cells using NleTDY-pNA as substrate assessed as cleavage of pNA at pH 7.2 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetChymase(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520050(CHEMBL4457132)
Affinity DataKi:  6.60nMAssay Description:Inhibition of recombinant human chymase expressed in Pichia pastoris X-33 cells using NleTDY-pNA as substrate assessed as cleavage of pNA at pH 7.2 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCathepsin G(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520058(CHEMBL4469390)
Affinity DataKi:  7.40nMAssay Description:Inhibition of human cathepsin G using Suc-AAPF-MCA as substrate at pH 7.2 and 298 K measured every 60 secs for 600 secsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetChymase(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520064(CHEMBL4590739)
Affinity DataKi:  7.5nMAssay Description:Inhibition of recombinant human chymase expressed in Pichia pastoris X-33 cells using NleTDY-pNA as substrate assessed as cleavage of pNA at pH 7.2 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCathepsin G(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520063(CHEMBL4586444)
Affinity DataKi:  8.20nMAssay Description:Inhibition of human cathepsin G using Suc-AAPF-MCA as substrate at pH 7.2 and 298 K measured every 60 secs for 600 secsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetChymase(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520066(CHEMBL4442550)
Affinity DataKi:  10nMAssay Description:Inhibition of recombinant human chymase expressed in Pichia pastoris X-33 cells using NleTDY-pNA as substrate assessed as cleavage of pNA at pH 7.2 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetChymotrypsinogen B2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520064(CHEMBL4590739)
Affinity DataKi:  11nMAssay Description:Inhibition of human chymotrypsin using Suc-AAPF-MCA as substrate at pH 8 and 298 K measured every 60 secs for 600 secsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetChymase(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520059(CHEMBL4561218)
Affinity DataKi:  11nMAssay Description:Inhibition of recombinant human chymase expressed in Pichia pastoris X-33 cells using NleTDY-pNA as substrate assessed as cleavage of pNA at pH 7.2 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCathepsin G(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520064(CHEMBL4590739)
Affinity DataKi:  14nMAssay Description:Inhibition of human cathepsin G using Suc-AAPF-MCA as substrate at pH 7.2 and 298 K measured every 60 secs for 600 secsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetChymase(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520052(CHEMBL4554739)
Affinity DataKi:  19nMAssay Description:Inhibition of recombinant human chymase expressed in Pichia pastoris X-33 cells using NleTDY-pNA as substrate assessed as cleavage of pNA at pH 7.2 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetChymase(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520058(CHEMBL4469390)
Affinity DataKi:  20nMAssay Description:Inhibition of recombinant human chymase expressed in Pichia pastoris X-33 cells using NleTDY-pNA as substrate assessed as cleavage of pNA at pH 7.2 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetChymase(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520057(CHEMBL4441622)
Affinity DataKi:  37nMAssay Description:Inhibition of recombinant human chymase expressed in Pichia pastoris X-33 cells using NleTDY-pNA as substrate assessed as cleavage of pNA at pH 7.2 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCathepsin G(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520050(CHEMBL4457132)
Affinity DataKi:  54nMAssay Description:Inhibition of human cathepsin G using Suc-AAPF-MCA as substrate at pH 7.2 and 298 K measured every 60 secs for 600 secsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetChymase(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520055(CHEMBL4464900)
Affinity DataKi:  54nMAssay Description:Inhibition of recombinant human chymase expressed in Pichia pastoris X-33 cells using NleTDY-pNA as substrate assessed as cleavage of pNA at pH 7.2 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetChymase(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520061(CHEMBL4556207)
Affinity DataKi:  54nMAssay Description:Inhibition of recombinant human chymase expressed in Pichia pastoris X-33 cells using NleTDY-pNA as substrate assessed as cleavage of pNA at pH 7.2 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetChymase(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50520053(CHEMBL4449838)
Affinity DataKi:  64nMAssay Description:Inhibition of recombinant human chymase expressed in Pichia pastoris X-33 cells using NleTDY-pNA as substrate assessed as cleavage of pNA at pH 7.2 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
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