Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50009754
TargetKallikrein-7(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM113069(US9695194, 5)
Affinity DataIC50: 48nMAssay Description:Inhibition of recombinant human KLK7 using S-2586 substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetKallikrein-14(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM113069(US9695194, 5)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human KLK14 using S-2302 substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetKallikrein-1(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50531895(CHEMBL4526462)
Affinity DataIC50: 126nMAssay Description:Inhibition of recombinant human N-terminal his-tagged KLK1 (19 to 262 residues) expressed in baculovirus infected sf9 insect cells using R110 labelle...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetKallikrein-5(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM113069(US9695194, 5)
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant human KLK5 using S-2288 substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetKallikrein-1(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50531896(CHEMBL4584434)
Affinity DataIC50: 251nMAssay Description:Inhibition of recombinant human N-terminal his-tagged KLK1 (19 to 262 residues) expressed in baculovirus infected sf9 insect cells using R110 labelle...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetKallikrein-1(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50531889(CHEMBL4476246)
Affinity DataIC50: 316nMAssay Description:Inhibition of recombinant human N-terminal his-tagged KLK1 (19 to 262 residues) expressed in baculovirus infected sf9 insect cells using R110 labelle...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetKallikrein-5(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50531889(CHEMBL4476246)
Affinity DataIC50: 501nMAssay Description:Inhibition of recombinant human FLAG-tagged KLK5 expressed in baculovirus infected sf9 insect cells using (Tos-Gly-Pro-Arg)2[R110].2TFA as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetKallikrein-1(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50115895(N-(4-Carbamimidoyl-phenyl)-3-chloro-2-hydroxy-benz...)
Affinity DataIC50: 631nMAssay Description:Inhibition of recombinant human N-terminal his-tagged KLK1 (19 to 262 residues) expressed in baculovirus infected sf9 insect cells using R110 labelle...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetKallikrein-5(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50531896(CHEMBL4584434)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human FLAG-tagged KLK5 expressed in baculovirus infected sf9 insect cells using (Tos-Gly-Pro-Arg)2[R110].2TFA as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetKallikrein-1(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50531900(CHEMBL4451358)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of recombinant human N-terminal his-tagged KLK1 (19 to 262 residues) expressed in baculovirus infected sf9 insect cells using R110 labelle...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetKallikrein-5(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50531892(CHEMBL4455170)
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of recombinant human FLAG-tagged KLK5 expressed in baculovirus infected sf9 insect cells using (Tos-Gly-Pro-Arg)2[R110].2TFA as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetKallikrein-5(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50115895(N-(4-Carbamimidoyl-phenyl)-3-chloro-2-hydroxy-benz...)
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of recombinant human FLAG-tagged KLK5 expressed in baculovirus infected sf9 insect cells using (Tos-Gly-Pro-Arg)2[R110].2TFA as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetKallikrein-5(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50531898(CHEMBL4439016)
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of recombinant human FLAG-tagged KLK5 expressed in baculovirus infected sf9 insect cells using (Tos-Gly-Pro-Arg)2[R110].2TFA as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetKallikrein-1(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50531892(CHEMBL4455170)
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of recombinant human N-terminal his-tagged KLK1 (19 to 262 residues) expressed in baculovirus infected sf9 insect cells using R110 labelle...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetKallikrein-1(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50115908(N-(4-Carbamimidoyl-phenyl)-2-hydroxy-3-methyl-benz...)
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of recombinant human N-terminal his-tagged KLK1 (19 to 262 residues) expressed in baculovirus infected sf9 insect cells using R110 labelle...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetKallikrein-1(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50531898(CHEMBL4439016)
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of recombinant human N-terminal his-tagged KLK1 (19 to 262 residues) expressed in baculovirus infected sf9 insect cells using R110 labelle...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetKallikrein-1(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50531891(CHEMBL4537596)
Affinity DataIC50: 5.01E+3nMAssay Description:Inhibition of recombinant human N-terminal his-tagged KLK1 (19 to 262 residues) expressed in baculovirus infected sf9 insect cells using R110 labelle...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetKallikrein-5(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50531895(CHEMBL4526462)
Affinity DataIC50: 5.01E+3nMAssay Description:Inhibition of recombinant human FLAG-tagged KLK5 expressed in baculovirus infected sf9 insect cells using (Tos-Gly-Pro-Arg)2[R110].2TFA as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetKallikrein-5(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM14155(N-(4-CARBAMIMIDOYL-PHENYL)-2-HYDROXY-BENZAMIDE | N...)
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of recombinant human FLAG-tagged KLK5 expressed in baculovirus infected sf9 insect cells using (Tos-Gly-Pro-Arg)2[R110].2TFA as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetKallikrein-5(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50531897(CHEMBL4464957)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of KLK5 (unknown origin) using Boc-Val-Pro-Arg-AMC substrate incubated for 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetKallikrein-5(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50115908(N-(4-Carbamimidoyl-phenyl)-2-hydroxy-3-methyl-benz...)
Affinity DataIC50: 7.94E+3nMAssay Description:Inhibition of recombinant human FLAG-tagged KLK5 expressed in baculovirus infected sf9 insect cells using (Tos-Gly-Pro-Arg)2[R110].2TFA as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetKallikrein-5(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50531894(CHEMBL4450431)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human FLAG-tagged KLK5 expressed in baculovirus infected sf9 insect cells using (Tos-Gly-Pro-Arg)2[R110].2TFA as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetKallikrein-5(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50531900(CHEMBL4451358)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human FLAG-tagged KLK5 expressed in baculovirus infected sf9 insect cells using (Tos-Gly-Pro-Arg)2[R110].2TFA as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetKallikrein-5(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50531893(CHEMBL4467450)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human FLAG-tagged KLK5 expressed in baculovirus infected sf9 insect cells using (Tos-Gly-Pro-Arg)2[R110].2TFA as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetKallikrein-5(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50522478(CHEMBL4453014)
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of recombinant human FLAG-tagged KLK5 expressed in baculovirus infected sf9 insect cells using (Tos-Gly-Pro-Arg)2[R110].2TFA as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetKallikrein-1(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50531890(CHEMBL4469753)
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of recombinant human N-terminal his-tagged KLK1 (19 to 262 residues) expressed in baculovirus infected sf9 insect cells using R110 labelle...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetKallikrein-5(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50531891(CHEMBL4537596)
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of recombinant human FLAG-tagged KLK5 expressed in baculovirus infected sf9 insect cells using (Tos-Gly-Pro-Arg)2[R110].2TFA as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetKallikrein-1(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM14155(N-(4-CARBAMIMIDOYL-PHENYL)-2-HYDROXY-BENZAMIDE | N...)
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of recombinant human N-terminal his-tagged KLK1 (19 to 262 residues) expressed in baculovirus infected sf9 insect cells using R110 labelle...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetKallikrein-5(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50531890(CHEMBL4469753)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant human FLAG-tagged KLK5 expressed in baculovirus infected sf9 insect cells using (Tos-Gly-Pro-Arg)2[R110].2TFA as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetKallikrein-5(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50531899(CHEMBL4585609)
Affinity DataIC50: 1.58E+5nMAssay Description:Inhibition of recombinant human FLAG-tagged KLK5 expressed in baculovirus infected sf9 insect cells using (Tos-Gly-Pro-Arg)2[R110].2TFA as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetKallikrein-1(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50522478(CHEMBL4453014)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of recombinant human N-terminal his-tagged KLK1 (19 to 262 residues) expressed in baculovirus infected sf9 insect cells using R110 labelle...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetKallikrein-1(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50531893(CHEMBL4467450)
Affinity DataIC50: 5.01E+5nMAssay Description:Inhibition of recombinant human N-terminal his-tagged KLK1 (19 to 262 residues) expressed in baculovirus infected sf9 insect cells using R110 labelle...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetKallikrein-1(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50531899(CHEMBL4585609)
Affinity DataIC50: 5.01E+5nMAssay Description:Inhibition of recombinant human N-terminal his-tagged KLK1 (19 to 262 residues) expressed in baculovirus infected sf9 insect cells using R110 labelle...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetKallikrein-1(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50531894(CHEMBL4450431)
Affinity DataIC50: 6.31E+5nMAssay Description:Inhibition of recombinant human N-terminal his-tagged KLK1 (19 to 262 residues) expressed in baculovirus infected sf9 insect cells using R110 labelle...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed