37 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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Synthesis and pharmacological characterization of novel N-(trans-4-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)cyclohexyl)amides as potential multireceptor atypical antipsychotics.
Shanghai Jiao Tong University
Identification of SENP1 inhibitors through in silico screening and rational drug design.
Shanghai Jiao Tong University
Discovery and analgesic evaluation of 8-chloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione as a novel potent d-amino acid oxidase inhibitor.
Shanghai Jiao Tong University
Development and evaluation of a highly reliable assay for SUMO-specific protease inhibitors.
Shanghai Jiao Tong University
Design and Synthesis of Newa-Naphthoflavones as Cytochrome P450 (CYP) 1B1 Inhibitors To Overcome Docetaxel-Resistance Associated with CYP1B1 Overexpression.
Shanghai Jiao Tong University
Crystal Structures of PI3Kα Complexed with PI103 and Its Derivatives: New Directions for Inhibitors Design.
Shanghai Jiao Tong University
The effect of absolute configuration on activity, subtype selectivity (M3/M2) of 3a-acyloxy-6ß-acetoxyltropane derivatives as muscarinic M3 receptor antagonists.
Shanghai Jiao Tong University
2-(4-Chlorophenyl)-2-oxoethyl 4-benzamidobenzoate derivatives, a novel class of SENP1 inhibitors: Virtual screening, synthesis and biological evaluation.
Shanghai Jiao Tong University
Design, synthesis, and evaluation of 2-substituted ethenesulfonic acid ester derivatives as protein tyrosine phosphatase 1B inhibitors.
Shanghai Jiao Tong University
Pharmacophore modeling and in silico screening for new KDR kinase inhibitors.
Shanghai Jiao Tong University
Design, synthesis, and biological evaluation of benzodiazepine-based SUMO-specific protease 1 inhibitors.
Shanghai Jiao Tong University
Design, Synthesis, and Pharmacological Evaluation of Multisubstituted Pyrido[4,3-
Shanghai Jiao Tong University
Design, Synthesis, and Pharmacological Evaluation of Isoindoline Analogues as New HPK1 Inhibitors.
Shanghai Jiao Tong University
Structural Modification and Pharmacological Evaluation of Substituted Quinoline-5,8-diones as Potent NSD2 Inhibitors.
Shanghai Jiao Tong University
Inhibition of vertebrate aldehyde oxidase as a therapeutic treatment for cancer, obesity, aging and amyotrophic lateral sclerosis.
Shanghai Jiao Tong University
Computational methods-guided design of modulators targeting protein-protein interactions (PPIs).
Shanghai Jiao Tong University
Piezo-Type Mechanosensitive Ion Channel Component 1 (Piezo1): A Promising Therapeutic Target and Its Modulators.
Shanghai Jiao Tong University
Design, synthesis and pharmacological evaluation of new PARP1 inhibitors by merging pharmacophores of olaparib and the natural product alantolactone.
Shanghai Jiao Tong University
Structure-Activity relationship study of benzothiophene oxobutanoic acid analogues leading to novel stimulator of interferon gene (STING) agonists.
Shanghai Jiao Tong University
Small molecules targeting cGAS-STING pathway for autoimmune disease.
Shanghai Jiao Tong University
Design, Synthesis, and Pharmacological Evaluation of Biaryl-Containing PD-1/PD-L1 Interaction Inhibitors Bearing a Unique Difluoromethyleneoxy Linkage.
Shanghai Jiao Tong University
Synthesis and biological evaluation of geniposide derivatives as potent and selective PTPlB inhibitors.
Shanghai Jiao Tong University
Benzothiophene-2-carboxamide derivatives as SENPs inhibitors with selectivity within SENPs family.
Shanghai Jiao Tong University
Discovery of heterocycle-containing α-naphthoflavone derivatives as water-soluble, highly potent and selective CYP1B1 inhibitors.
Shanghai Jiao Tong University
Structural optimization of pyrazolo[1,5-a]pyrimidine derivatives as potent and highly selective DPP-4 inhibitors.
Shanghai Jiao Tong University
Discovery of a Bioactive Inhibitor with a New Scaffold for Cystathionine γ-Lyase.
Shanghai Jiao Tong University
Cinerols, Nitrogenous Meroterpenoids from the Marine Sponge
Shanghai Jiao Tong University
Inhibition of polypeptide N-acetyl-α-galactosaminyltransferases is an underlying mechanism of dietary polyphenols preventing colorectal tumorigenesis.
Shanghai Jiao Tong University
Synthesis and structure-activity relationship studies of α-naphthoflavone derivatives as CYP1B1 inhibitors.
Shanghai Jiao Tong University
Small Molecule Allosteric Modulators of G-Protein-Coupled Receptors: Drug-Target Interactions.
Shanghai Jiao Tong University
Surrogating and redirection of pyrazolo[1,5-a]pyrimidin-7(4H)-one core, a novel class of potent and selective DPP-4 inhibitors.
Shanghai Jiao Tong University
Sesquiterpene Quinones/Hydroquinones from the Marine Sponge Spongia pertusa Esper.
Shanghai Jiao Tong University
Development of a highly reliable assay for ubiquitin-specific protease 2 inhibitors.
Shanghai Jiao Tong University
Y-shaped bis-arylethenesulfonic acid esters: Potential potent and membrane permeable protein tyrosine phosphatase 1B inhibitors.
Shanghai Jiao Tong University
