Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50014309
TargetKappa-type opioid receptor(Mouse)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM50574769(CHEMBL4870603)
Affinity DataEC50:  17nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as inhibition of forskolin in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM50574769(CHEMBL4870603)
Affinity DataEC50:  1.04E+4nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as beta-arrestin recruitment ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM50000296(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)
Affinity DataEC50:  4.89E+3nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as beta-arrestin recruitment ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM50574769(CHEMBL4870603)
Affinity DataEC50:  0.5nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as inhibition of forskolin in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM50574769(CHEMBL4870603)
Affinity DataEC50:  1nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as inhibition of forskolin in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM50574769(CHEMBL4870603)
Affinity DataEC50:  0.900nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as inhibition of forskolin in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM50574769(CHEMBL4870603)
Affinity DataEC50:  0.900nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as inhibition of forskolin in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM50574769(CHEMBL4870603)
Affinity DataEC50:  0.900nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as inhibition of forskolin in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM50574769(CHEMBL4870603)
Affinity DataEC50:  0.800nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as inhibition of forskolin in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM50000296(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)
Affinity DataEC50:  1.70nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as inhibition of forskolin in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM50574769(CHEMBL4870603)
Affinity DataEC50:  8.80nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as inhibition of forskolin in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM50574769(CHEMBL4870603)
Affinity DataEC50:  8.80nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as inhibition of forskolin in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM50574769(CHEMBL4870603)
Affinity DataEC50:  5nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as inhibition of forskolin in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataEC50:  6.70nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as inhibition of forskolin in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM50574769(CHEMBL4870603)
Affinity DataEC50:  2.40E+4nMAssay Description:Agonist activity at mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as inhibition of forskolin induced cAMP production ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataEC50:  159nMAssay Description:Agonist activity at mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as beta-arrestin 2 recruitment using furimazine as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM50574769(CHEMBL4870603)
Affinity DataEC50:  6.80nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as inhibition of forskolin in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM50574768(CHEMBL4848577)
Affinity DataEC50:  6.02E+4nMAssay Description:Agonist activity at mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as inhibition of forskolin induced cAMP production ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM50574769(CHEMBL4870603)
Affinity DataKi:  0.200nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as binding affinity of dyn A1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM50574769(CHEMBL4870603)
Affinity DataKi:  0.300nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as binding affinity of dyn A1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM214798(YGGFLRRIRPKLK | Dynorphin A (1-17))
Affinity DataKi:  0.300nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as binding affinity of dyn A1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM50574769(CHEMBL4870603)
Affinity DataKi:  0.400nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as binding affinity of dyn A1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM50574769(CHEMBL4870603)
Affinity DataKi:  0.400nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as binding affinity of dyn A1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM50574769(CHEMBL4870603)
Affinity DataKi:  0.400nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as binding affinity of dyn A1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM50000296(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)
Affinity DataKi:  8.10nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as binding affinity of U50,48...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM50574769(CHEMBL4870603)
Affinity DataKi:  10nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as binding affinity of U50,48...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM50574769(CHEMBL4870603)
Affinity DataKi:  15nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as binding affinity of U50,48...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM50574769(CHEMBL4870603)
Affinity DataKi:  15nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as binding affinity of U50,48...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM50574769(CHEMBL4870603)
Affinity DataKi:  17nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as binding affinity of U50,48...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM50574769(CHEMBL4870603)
Affinity DataKi:  36nMAssay Description:Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as binding affinity of U50,48...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM50574768(CHEMBL4848577)
Affinity DataKi:  1.20E+3nMAssay Description:Displacement of [3H]-DPN from mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as inhibition constant incubated for 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM50574769(CHEMBL4870603)
Affinity DataKi:  2.00E+3nMAssay Description:Displacement of [3H]-DPN from mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as inhibition constant incubated for 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed