Target Names are taken from UniProtKB. To view the associated UniProt page, click on the UniProt ID. When we have data for a given Target in multiple species or for mutants of a given Target, we provide a header row (upper case, bold font) with all of the data followed by a separate for each species or variant of the Target.
Human
Kd: 98
Human
Human
Human
Baculoviral IAP repeat-containing protein 2/Baculoviral IAP repeat-containing protein 3/E3 ubiquitin-protein ligase XIAP P98170 Q13489 Q13490
Human
IC50: 30
Human
Human
IC50: 128
Human
IC50: 67
Human
BETA-1 ADRENERGIC RECEPTOR A0A4Y6F0G0 B0FL73 P07550 P08588 P10608 P13945 P18090 P26255 P34971 Q28998
Human
BETA-2 ADRENERGIC RECEPTOR P07550 P08588 P10608 P13945 P18090 P18762 P26255 P54833 Q28044 Q8K4Z4 Q9BFY9
Human
Rat
Human
Human
Rat
BETA-GALACTOSIDASE A0A0E1EGE5 A4XI97 B7VU80 D3ZUM4 P00722 P16278 P23780 P29853 Q2U7N3 Q58D55 Q59750 Q8VNN2
Caldicellulosiruptor saccharolyticus (strain ATCC 43494 / DSM 8903)
IC50: 5
BETA-GLUCURONIDASE A0A0E1EGE5 A3KMY8 A4XI97 B7VU80 D3ZUM4 P00722 P05804 P06760 P08236 P12265 P16278 P23780 P29853 Q2U7N3 Q58D55 Q59750 Q8VNN2 Q8XP19
Caldicellulosiruptor saccharolyticus (strain ATCC 43494 / DSM 8903)
IC50: 5
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228)
Ki: 5
Enterococcus faecalis (strain ATCC 700802 / V583)
IC50: 89
Streptococcus pyogenes serotype M3
IC50: 4
Staphylococcus aureus (strain NCTC 8325 / PS 47)
IC50: 4
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
IC50: 4
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
IC50: 5
BETA-LACTAMASE A0ZX81 A1E3K9 A2RP81 A3FFR5 A4KCT8 A4ZYU9 A8DS27 A8RR46 B2ZTR6 B8R6A5 D1MIX9 D2SSQ3 D5HSX5 D6NSM8 F0KJS2 I7AKP2 O31272 P00807 P00808 P00811 P05193 P05364 P24735 P30897 P94958 P9WKD2 Q0VTR6 Q0VTR8 Q0VTS0 Q2QC95 Q2V0Y6 Q2XPY6 Q3LG62 Q3SAW3 Q44079 Q46991 Q48435 Q4GY26 Q4TVR4 Q53TY8 Q59401 Q5J463 Q670S6 Q6GWS8 Q6JP75 Q6REX6 Q6XEC0 Q79MP6 Q7B899 Q7X575 Q83YP9 Q840M4 Q8KZP2 Q8RLA6 Q8RT60 Q932Y6 Q93T40 Q9EXV5 Q9L5C7 Q9L5C8
Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67
IC50: 93
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228)
Pseudomonas aeruginosa (g-Proteobacteria)
BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE A7UD81 O02604 P07382 P13922 Q07422 Q27552 Q27713 Q27783 Q27793 Q582G3 Q8I1R6
Trypanosoma brucei brucei
IC50: 11
Cryptosporidium parvum
IC50: 87
malaria parasite P. vivax
Plasmodium Falciparum
Plasmodium Falciparum
Leishmania major
Toxoplasma gondii
IC50: 1364
malaria parasite P. falciparum
Ki: 31
Plasmodium berghei (strain Anka)
IC50: 5
Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
IC50: 34
Trypanosoma cruzi
malaria parasite P. vivax
malaria parasite P. falciparum
Ki: 31
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
IC50: 5
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
IC50: 1
Human
Clostridium botulinum
Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A)
Human
Human
Human
IC50: 371

