The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.1M data for 1.3M Compounds and 9.6K Targets. Of those, 1.5M data for 698K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

If BindingDB was of value to your research, please take a moment to donate to this nonprofit project. Your donation will let us provide you with more data and improved service.

To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

20 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
NTS2-selective neurotensin mimetics with tetrahydrofuran amino acids.EBI
University of Regensburg
Discovery of a novel small molecule agonist scaffold for the APJ receptor.EBI
Rti International
Mimicking of Arginine by Functionalized N(¿)-Carbamoylated Arginine As a New Broadly Applicable Approach to Labeled Bioactive Peptides: High Affinity Angiotensin, Neuropeptide Y, Neuropeptide FF, and Neurotensin Receptor Ligands As Examples.EBI
University of Regensburg
Synthesis and Characterization in Vitro and in Vivo of (l)-(Trimethylsilyl)alanine Containing Neurotensin Analogues.EBI
University of Montpellier
The amide linker in nonpeptide neurotensin receptor ligands plays a key role in calcium signaling at the neurotensin receptor type 2.EBI
Rti International
Identification of N-{[6-chloro-4-(2,6-dimethoxyphenyl)quinazolin-2-yl]carbonyl}-l-leucine (NTRC-808), a novel nonpeptide chemotype selective for the neurotensin receptor type 2.EBI
Research Triangle Institute
Identification of N-[(5-{[(4-methylphenyl)sulfonyl]amino}-3-(trifluoroacetyl)-1H-indol-1-yl)acetyl]-l-leucine (NTRC-824), a neurotensin-like nonpeptide compound selective for the neurotensin receptor type 2.EBI
Research Triangle Institute
Identification of 1-({[1-(4-fluorophenyl)-5-(2-methoxyphenyl)-1H-pyrazol-3-yl]carbonyl}amino)cyclohexane carboxylic acid as a selective nonpeptide neurotensin receptor type 2 compound.EBI
Research Triangle Institute
Imidazole-derived agonists for the neurotensin 1 receptor.EBI
Sanford-Burnham Medical Research Institute
In vitro analysis of stable, receptor-selective neurotensin[8-13] analogues.EBI
Medical University of South Carolina
Discovery of highly potent and neurotensin receptor 2 selective neurotensin mimetics.EBI
Friedrich-Alexander University
Identification and functional characterization of a stable, centrally active derivative of the neurotensin (8-13) fragment as a potential first-in-class analgesic.EBI
Medical University of South Carolina Campus
Neurotensin(8-13) analogs as dual NTS1 and NTS2 receptor ligands with enhanced effects on a mouse model of Parkinson's disease.EBI
University of Bonn
Pseudoprolines as stereoelectronically tunable proline isosteres.EBI
Bristol Myers Squibb
Development of disulfide-functionalized peptides covalently binding G protein-coupled receptors.EBI
Friedrich-Alexander Universit£T Erlangen-N£Rnberg
Design, Structural Optimization, and Characterization of the First Selective Macrocyclic Neurotensin Receptor Type 2 Non-opioid Analgesic.EBI
University of Sherbrooke
Optimized Opioid-Neurotensin Multitarget Peptides: From Design to Structure-Activity Relationship Studies.EBI
Vrije Universiteit Brussel
Fluorescence Labeling of Neurotensin(8-13) via Arginine Residues Gives Molecular Tools with High Receptor Affinity.EBI
University of Regensburg
Use of Molecular Modeling to Design Selective NTS2 Neurotensin Analogues.EBI
University of Montpellier
Design, synthesis, and pharmacological evaluation of N-bicyclo-5-chloro-1H-indole-2-carboxamide derivatives as potent glycogen phosphorylase inhibitors.BDB
Astellas Pharma