Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 50018314
TargetNeurotensin receptor type 1(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50342242((S)-2-((2S,3S)-2-((S)-2-((S)-1-((S)-6-amino-2-((S)...)
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of human NTR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetNeurotensin receptor type 1(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50130880(pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-L...)
Affinity DataIC50: 0.160nMAssay Description:Inhibition of human NTR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDipeptidyl peptidase 4(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50421791(CHEMBL5267798)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of DPP4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetNeurotensin receptor type 2(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50342242((S)-2-((2S,3S)-2-((S)-2-((S)-1-((S)-6-amino-2-((S)...)
Affinity DataIC50: 0.470nMAssay Description:Inhibition of human NTR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDipeptidyl peptidase 4(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50421792(CHEMBL5287917)
Affinity DataIC50: 0.480nMAssay Description:Inhibition of DPP4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetNeurotensin receptor type 2(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50130880(pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-L...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human NTR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM793(Noa-Asn-Apns-Dmt-NH-tBu | (2S)-N-[(2S,3S)-4-[(4R)-...)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of HIV1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetNeurotensin receptor type 2(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50124143(CHEMBL3622806)
Affinity DataIC50: 5nMAssay Description:Inhibition of human NTR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetIntegrin alpha-2(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50421786(CHEMBL5277760)
Affinity DataIC50: 6nMAssay Description:Inhibition of alpha2beta1 integrin-mediated cell adhesion to type 1 collagen in human platelets incubated for 30 mins in presence of ADP by microplat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetAngiotensin-converting enzyme(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50406931(RENTIAPRIL)
Affinity DataIC50: 6nMAssay Description:Inhibition of ACE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetAngiotensin-converting enzyme(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM21642((2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolid...)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of ACE (unknown origin) using tripeptide Hip-His-Leu-OH as substrate incubated for 4 mins by fluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM579(Kynostatin 272 | CHEMBL414640 | (4R)-N-tert-butyl-...)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of HIV1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50421790(CHEMBL5271231)
Affinity DataIC50: 8.80nMAssay Description:Inhibition of HIV1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetIntegrin alpha-2(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50421788(CHEMBL5266636)
Affinity DataIC50: 12nMAssay Description:Inhibition of alpha2beta1 integrin-mediated cell adhesion to type 1 collagen in human platelets incubated for 30 mins in presence of ADP by microplat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetIntegrin alpha-2(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50421760(CHEMBL5266675)
Affinity DataIC50: 17nMAssay Description:Inhibition of alpha2beta1 integrin-mediated cell adhesion to type 1 collagen in human platelets incubated for 30 mins in presence of ADP by microplat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetNeurotensin receptor type 1(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50124143(CHEMBL3622806)
Affinity DataIC50: 18nMAssay Description:Inhibition of human NTR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProlyl endopeptidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50421793(CHEMBL5282548)
Affinity DataIC50: 20nMAssay Description:Inhibition of POP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetIntegrin alpha-2(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50421785(CHEMBL5286317)
Affinity DataIC50: 25nMAssay Description:Inhibition of alpha2beta1 integrin-mediated cell adhesion to type 1 collagen in human platelets incubated for 30 mins in presence of ADP by microplat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetAngiotensin-converting enzyme(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM21642((2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolid...)
Affinity DataIC50: 30nMAssay Description:Inhibition of ACE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50421789(CHEMBL5270344)
Affinity DataIC50: 31nMAssay Description:Inhibition of HIV1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50421703(CHEMBL429088)
Affinity DataIC50: 67nMAssay Description:Inhibition of alpha2beta1 integrin-mediated cell adhesion to type 1 collagen in human platelets incubated for 30 mins in presence of ADP by microplat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetIntegrin alpha-2(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50421704(CHEMBL5276382)
Affinity DataIC50: 82nMAssay Description:Inhibition of alpha2beta1 integrin-mediated cell adhesion to type 1 collagen in human platelets incubated for 30 mins in presence of ADP by microplat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM4215(benzyl N-[(1S)-1-{[(2S,3S)-4-[(2S)-2-(tert-butylca...)
Affinity DataIC50: 89nMAssay Description:Inhibition of HIV1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetIntegrin alpha-2(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50421787(CHEMBL5276876)
Affinity DataIC50: 180nMAssay Description:Inhibition of alpha2beta1 integrin-mediated cell adhesion to type 1 collagen in human platelets incubated for 30 mins in presence of ADP by microplat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProlyl endopeptidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50312223((2R,5S,7R)-1-Aza-7-benzyloxycarbonylamino-8-oxo-4-...)
Affinity DataIC50: 200nMAssay Description:Inhibition of POP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProlyl endopeptidase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50421794(CHEMBL1079473)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of POP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM580(AG1776 | (4R)-3-[(2S,3S)-2-hydroxy-3-[(3-hydroxy-2...)
Affinity DataKi:  0.330nMAssay Description:Inhibition of HIV1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM579(Kynostatin 272 | CHEMBL414640 | (4R)-N-tert-butyl-...)
Affinity DataKi:  0.740nMAssay Description:Inhibition of HIV1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetType-2 angiotensin II receptor(Rat)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50421796(CHEMBL5286105)
Affinity DataKi:  1nMAssay Description:Displacement of [I125I]AngII form AT2 receptor in rat liver membrane incubated for 1.5 hrs by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetType-1 angiotensin II receptor A(Rat)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50421795(CHEMBL5274111)
Affinity DataKi:  1.10nMAssay Description:Displacement of [I125I]AngII form AT1 receptor in rat liver membrane incubated for 1.5 hrs by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetType-2 angiotensin II receptor(Rat)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50421795(CHEMBL5274111)
Affinity DataKi:  1.20nMAssay Description:Displacement of [I125I]AngII form AT2 receptor in rat liver membrane incubated for 1.5 hrs by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetAngiotensin-converting enzyme(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50406931(RENTIAPRIL)
Affinity DataKi:  2.20nMAssay Description:Inhibition of ACE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetType-2 angiotensin II receptor(Rat)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50421797(CHEMBL5286767)
Affinity DataKi:  3.70nMAssay Description:Displacement of [I125I]AngII form AT2 receptor in rat liver membrane incubated for 1.5 hrs by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetType-1 angiotensin II receptor A(Rat)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50421796(CHEMBL5286105)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [I125I]AngII form AT1 receptor in rat liver membrane incubated for 1.5 hrs by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetType-1 angiotensin II receptor A(Rat)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50421797(CHEMBL5286767)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [I125I]AngII form AT1 receptor in rat liver membrane incubated for 1.5 hrs by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed