Compile Data Set for Download or QSAR
Report error Found 132 Enz. Inhib. hit(s) with all data for entry = 50012061
TargetMu-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50070386(CHEMBL3408737)
Affinity DataEC50:  0.100nMAssay Description:Agonist activity at human MOR stably expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 1 hr by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50553766(CHEMBL4761165)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human MOR stably expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 1 hr by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50553767(CHEMBL4789659)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human MOR stably expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 1 hr by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50553768(CHEMBL4744531)
Affinity DataEC50:  65nMAssay Description:Agonist activity at human MOR stably expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 1 hr by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50553769(CHEMBL4798887)
Affinity DataEC50:  9.10nMAssay Description:Agonist activity at human MOR stably expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 1 hr by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50553770(CHEMBL4758754)
Affinity DataEC50:  49nMAssay Description:Agonist activity at human MOR stably expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 1 hr by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50553771(CHEMBL4776986)
Affinity DataEC50:  29nMAssay Description:Agonist activity at human MOR stably expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 1 hr by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50553772(CHEMBL4749016)
Affinity DataEC50:  65nMAssay Description:Agonist activity at human MOR stably expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 1 hr by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50553773(CHEMBL4742666)
Affinity DataEC50:  4.60nMAssay Description:Agonist activity at human MOR stably expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 1 hr by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50553774(CHEMBL4750783)
Affinity DataEC50:  46nMAssay Description:Agonist activity at human MOR stably expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 1 hr by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50553775(CHEMBL4745899)
Affinity DataEC50:  6.5nMAssay Description:Agonist activity at human MOR stably expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 1 hr by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50553776(CHEMBL4747286)
Affinity DataEC50:  27nMAssay Description:Agonist activity at human MOR stably expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 1 hr by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50070386(CHEMBL3408737)
Affinity DataEC50:  5.5nMAssay Description:Agonist activity at human MOR expressed in human U2OS cells assessed as increase in beta arrestin2 recruitment incubated for 90 mins by pathhunter be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50553766(CHEMBL4761165)
Affinity DataEC50:  956nMAssay Description:Agonist activity at human MOR expressed in human U2OS cells assessed as increase in beta arrestin2 recruitment incubated for 90 mins by pathhunter be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50553767(CHEMBL4789659)
Affinity DataEC50:  1.33E+3nMAssay Description:Agonist activity at human MOR expressed in human U2OS cells assessed as increase in beta arrestin2 recruitment incubated for 90 mins by pathhunter be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50553768(CHEMBL4744531)
Affinity DataEC50:  2.46E+3nMAssay Description:Agonist activity at human MOR expressed in human U2OS cells assessed as increase in beta arrestin2 recruitment incubated for 90 mins by pathhunter be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50553769(CHEMBL4798887)
Affinity DataEC50:  1.14E+3nMAssay Description:Agonist activity at human MOR expressed in human U2OS cells assessed as increase in beta arrestin2 recruitment incubated for 90 mins by pathhunter be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50553770(CHEMBL4758754)
Affinity DataEC50:  1.97E+3nMAssay Description:Agonist activity at human MOR expressed in human U2OS cells assessed as increase in beta arrestin2 recruitment incubated for 90 mins by pathhunter be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50553771(CHEMBL4776986)
Affinity DataEC50:  1.07E+3nMAssay Description:Agonist activity at human MOR expressed in human U2OS cells assessed as increase in beta arrestin2 recruitment incubated for 90 mins by pathhunter be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50553772(CHEMBL4749016)
Affinity DataEC50:  3.04E+3nMAssay Description:Agonist activity at human MOR expressed in human U2OS cells assessed as increase in beta arrestin2 recruitment incubated for 90 mins by pathhunter be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50553773(CHEMBL4742666)
Affinity DataEC50:  934nMAssay Description:Agonist activity at human MOR expressed in human U2OS cells assessed as increase in beta arrestin2 recruitment incubated for 90 mins by pathhunter be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50553774(CHEMBL4750783)
Affinity DataEC50:  2.16E+3nMAssay Description:Agonist activity at human MOR expressed in human U2OS cells assessed as increase in beta arrestin2 recruitment incubated for 90 mins by pathhunter be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50553775(CHEMBL4745899)
Affinity DataEC50:  359nMAssay Description:Agonist activity at human MOR expressed in human U2OS cells assessed as increase in beta arrestin2 recruitment incubated for 90 mins by pathhunter be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50553776(CHEMBL4747286)
Affinity DataEC50:  1.27E+3nMAssay Description:Agonist activity at human MOR expressed in human U2OS cells assessed as increase in beta arrestin2 recruitment incubated for 90 mins by pathhunter be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50070386(CHEMBL3408737)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at human DOR stably expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 1 hr by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50553766(CHEMBL4761165)
Affinity DataEC50:  479nMAssay Description:Agonist activity at human DOR stably expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 1 hr by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50553767(CHEMBL4789659)
Affinity DataEC50:  301nMAssay Description:Agonist activity at human DOR stably expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 1 hr by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50553768(CHEMBL4744531)
Affinity DataEC50:  1.32E+3nMAssay Description:Agonist activity at human DOR stably expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 1 hr by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50553769(CHEMBL4798887)
Affinity DataEC50:  313nMAssay Description:Agonist activity at human DOR stably expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 1 hr by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50553770(CHEMBL4758754)
Affinity DataEC50:  898nMAssay Description:Agonist activity at human DOR stably expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 1 hr by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50553771(CHEMBL4776986)
Affinity DataEC50:  305nMAssay Description:Agonist activity at human DOR stably expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 1 hr by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50553772(CHEMBL4749016)
Affinity DataEC50:  248nMAssay Description:Agonist activity at human DOR stably expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 1 hr by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50553773(CHEMBL4742666)
Affinity DataEC50:  227nMAssay Description:Agonist activity at human DOR stably expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 1 hr by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50553774(CHEMBL4750783)
Affinity DataEC50:  842nMAssay Description:Agonist activity at human DOR stably expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 1 hr by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50553775(CHEMBL4745899)
Affinity DataEC50:  177nMAssay Description:Agonist activity at human DOR stably expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 1 hr by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50553776(CHEMBL4747286)
Affinity DataEC50:  452nMAssay Description:Agonist activity at human DOR stably expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 1 hr by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50070386(CHEMBL3408737)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human KOR stably expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 1 hr by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50553766(CHEMBL4761165)
Affinity DataEC50:  47nMAssay Description:Agonist activity at human KOR stably expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 1 hr by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50553767(CHEMBL4789659)
Affinity DataEC50:  514nMAssay Description:Agonist activity at human KOR stably expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 1 hr by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50553768(CHEMBL4744531)
Affinity DataEC50:  1.65E+3nMAssay Description:Agonist activity at human KOR stably expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 1 hr by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50553769(CHEMBL4798887)
Affinity DataEC50:  415nMAssay Description:Agonist activity at human KOR stably expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 1 hr by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50553770(CHEMBL4758754)
Affinity DataEC50:  1.57E+3nMAssay Description:Agonist activity at human KOR stably expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 1 hr by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50553771(CHEMBL4776986)
Affinity DataEC50:  158nMAssay Description:Agonist activity at human KOR stably expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 1 hr by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50553772(CHEMBL4749016)
Affinity DataEC50:  239nMAssay Description:Agonist activity at human KOR stably expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 1 hr by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50553773(CHEMBL4742666)
Affinity DataEC50:  399nMAssay Description:Agonist activity at human KOR stably expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 1 hr by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50553774(CHEMBL4750783)
Affinity DataEC50:  1.56E+3nMAssay Description:Agonist activity at human KOR stably expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 1 hr by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50553775(CHEMBL4745899)
Affinity DataEC50:  424nMAssay Description:Agonist activity at human KOR stably expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 1 hr by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50553776(CHEMBL4747286)
Affinity DataEC50:  401nMAssay Description:Agonist activity at human KOR stably expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 1 hr by liquid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetNeurotensin receptor type 1(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50048908(CHEMBL415788)
Affinity DataEC50:  0.150nMAssay Description:Agonist activity at human NTS1 expressed in HEK293 cells co-expressing Galphaq/RlucII/GFP10-Ggamma1/Gbeta1 assessed as increase in Galphaq activation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetNeurotensin receptor type 1(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50553766(CHEMBL4761165)
Affinity DataEC50:  19nMAssay Description:Agonist activity at human NTS1 expressed in HEK293 cells co-expressing Galphaq/RlucII/GFP10-Ggamma1/Gbeta1 assessed as increase in Galphaq activation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
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