BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.5M data for 737K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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16 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Application of desirability-based multi(bi)-objective optimization in the design of selective arylpiperazine derivates for the 5-HT1A serotonin receptor.EBI
University of Porto
Boosting caffeic acid performance as antioxidant and monoamine oxidase B/catechol-O-methyltransferase inhibitor.EBI
University of Porto
Design and synthesis of chromone-based monoamine oxidase B inhibitors with improved drug-like properties.EBI
University of Porto
Bis-chalcones: A review of synthetic methodologies and anti-inflammatory effects.EBI
University of Porto
Discovery of New Potent Positive Allosteric Modulators of Dopamine DEBI
University of Porto
Development of potent CPP6-gemcitabine conjugates against human prostate cancer cell line (PC-3).EBI
University of Porto
Structural Specificity of Flavonoids in the Inhibition of Human Fructose 1,6-Bisphosphatase.EBI
University of Porto
Discovery of New Chemical Entities for Old Targets: Insights on the Lead Optimization of Chromone-Based Monoamine Oxidase B (MAO-B) Inhibitors.EBI
University of Porto
Development of Blood-Brain Barrier Permeable Nitrocatechol-Based Catechol O-Methyltransferase Inhibitors with Reduced Potential for Hepatotoxicity.EBI
University of Porto
Benzoic acid-derived nitrones: A new class of potential acetylcholinesterase inhibitors and neuroprotective agents.EBI
University of Porto
Structure-Based Optimization of Coumarin hAEBI
University of Porto
Design of novel monoamine oxidase-B inhibitors based on piperine scaffold: Structure-activity-toxicity, drug-likeness and efflux transport studies.EBI
University of Porto
Multi-target-directed ligands for Alzheimer's disease: Discovery of chromone-based monoamine oxidase/cholinesterase inhibitors.EBI
University of Porto
Tight-Binding Inhibition of Human Monoamine Oxidase B by Chromone Analogs: A Kinetic, Crystallographic, and Biological Analysis.EBI
University of Porto
Coumarin versus Chromone Monoamine Oxidase B Inhibitors: Quo Vadis?EBI
University of Porto
Chromone as a Privileged Scaffold in Drug Discovery: Recent Advances.EBI
University of Porto