Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50000106
TargetAmine oxidase [flavin-containing] B(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50350110(CHEMBL1814068)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human MAO-B using p-tyramine as substrate by amplex red-based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50240678(CHEMBL4077771)
Affinity DataIC50: 42nMAssay Description:Inhibition of human MAO-B using p-tyramine as substrate by amplex red-based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50240677(CHEMBL4080202)
Affinity DataIC50: 270nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated with substrate for 15 mins followed by protein addition meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50240676(CHEMBL4077452)
Affinity DataIC50: 960nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated with substrate for 15 mins followed by protein addition meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50240681(CHEMBL4066788)
Affinity DataIC50: 6.84E+3nMAssay Description:Inhibition of recombinant human BACE-1 using rhodamine labelled EVNLDAEFK as substrate after 90 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed