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BindingDB contains 3.1M data for 1.3M Compounds and 9.6K Targets. Of those, 1.5M data for 698K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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40 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Novel 3-(1H-indol-3-yl)-2-[3-(4-methoxyphenyl)ureido]propanamides as selective agonists of human formyl-peptide receptor 2.EBI
University of Bari Aldo Moro
Pachymodulin, a new functional formyl peptide receptor 2 peptidic ligand isolated from frog skin has Janus-like immunomodulatory capacities.EBI
Sorbonne University
Development of potent antagonists for formyl peptide receptor 1 based on Boc-Phe-D-Leu-Phe-D-Leu-Phe-OH.EBI
Saga University
Discovery of 2-[5-(4-Fluorophenylcarbamoyl)pyridin-2-ylsulfanylmethyl]phenylboronic Acid (SX-517): Noncompetitive Boronic Acid Antagonist of CXCR1 and CXCR2.EBI
Syntrix Biosystems
Lead optimisation of pyrazoles as novel FPR1 antagonists.EBI
Astrazeneca
Discovery of pyrazoles as novel FPR1 antagonists.EBI
Astrazeneca
Discovery of small molecule human FPR1 receptor antagonists.EBI
Astrazeneca
2-Phenyl-2,3-dihydro-1H-imidazo[1,2-b]pyrazole derivatives: new potent inhibitors of fMLP-induced neutrophil chemotaxis.EBI
University of Genoa
Cyclosporins: structure-activity relationships for the inhibition of the human FPR1 formylpeptide receptor.EBI
Strasbourg 1 University
6-methyl-2,4-disubstituted pyridazin-3(2H)-ones: a novel class of small-molecule agonists for formyl peptide receptors.EBI
Universita Degli Studi Di Firenze
Fused Tetrahydroquinolines Are Interfering with Your Assay.EBI
University of North Carolina At Chapel Hill
Development of potent isoflavone-based formyl peptide receptor 1 (FPR1) antagonists and their effects in gastric cancer cell models.EBI
University of Bari Aldo Moro
Recent advances in the design and development of formyl peptide receptor 2 (FPR2/ALX) agonists as pro-resolving agents with diverse therapeutic potential.EBI
Queen Mary University of London
Design, Synthesis, Biological Evaluation, and Computational Studies of Novel Ureidopropanamides as Formyl Peptide Receptor 2 (FPR2) Agonists to Target the Resolution of Inflammation in Central Nervous System Disorders.EBI
University of Bari Aldo Moro
Discovery of Heteroaryl Urea Isosteres for Formyl Peptide Receptor 2 Agonists.EBI
Bristol Myers Squibb Research and Development
Design, synthesis, and biological evaluation of novel pyrrolidinone small-molecule Formyl peptide receptor 2 agonists.EBI
Queen Mary University of London
Discovery of BMS-986235/LAR-1219: A Potent Formyl Peptide Receptor 2 (FPR2) Selective Agonist for the Prevention of Heart Failure.EBI
Kyorin Pharmaceutical
Substituted Pyridazin-3(2 H)-ones as Highly Potent and Biased Formyl Peptide Receptor Agonists.EBI
Monash University
Preventing Morphine-Seeking Behavior through the Re-Engineering of Vincamine's Biological Activity.EBI
University of Florida
N-terminus urea-substituted chemotactic peptides: new potent agonists and antagonists toward the neutrophil fMLF receptor.EBI
Johnson Matthey Biomedical Research
Novel ureidopropanamide based N-formyl peptide receptor 2 (FPR2) agonists with potential application for central nervous system disorders characterized by neuroinflammation.EBI
University of Bari Aldo Moro
Streptococcus mutans glucosyl transferase inhibitors for dental caries therapyBDB
Uab Research Foundation
CASEIN KINASE 1 DELTA MODULATORSBDB
Janssen Pharmaceutica
PHD INHIBITOR COMPOUNDS, COMPOSITIONS, AND METHODS OF USEBDB
Akebia Therapeutics
Protacs based on VHL ligand targeting coronavirus 3CL protease and preparation method and application thereofBDB
Shaanxi Panlong Pharmaceutical
Galactopyranosyl-cyclohexyl derivauves as E-selectin antagonistsBDB
Glycomimetics.
Sultam compound and application method thereofBDB
Chai Tai Tianqing Pharmaceutical Group
Substituted tricyclic compounds as FGFR inhibitorsBDB
Incyte
Compounds and their uses as ACC inhibitorsBDB
Nanjing Ruijie Pharmatech
Selective Bruton's tyrosine kinase inhibitor and use thereofBDB
Hangzhou Hertz Pharmaceutical
CompoundsBDB
Exonate
3-oxo-tetrahydro-furo[3,2-b]pyrrol-4(5H)-yl) derivatives IIBDB
GrÜNenthal
C-6 spirocarbocyclic iminothiadiazine dioxides as BACE inhibitors, compositions, and their useBDB
Merck Sharp & Dohme
Dihydroquinoline pyrazolyl compoundsBDB
Hoffmann-La Roche
ERK inhibitors and uses thereofBDB
Celgene Car
Definition of peptide inhibitors from a synthetic peptide library by targeting gelatinase B/matrix metalloproteinase-9 (MMP-9) and TNF-a converting enzyme (TACE/ADAM-17).BDB
China Pharmaceutical University
Rapid behavior-based identification of neuroactive small molecules in the zebrafish.BDB
Harvard Medical School
Structure-activity relationship studies of a series of peptidomimetic ligands for alpha(4) beta(1) integrin on Jurkat T-leukemia cells.BDB
University of California Davis
Design and synthesis of hydroxyethylene-based peptidomimetic inhibitors of human beta-secretase.BDB
Elan Pharmaceuticals