Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 50021579
TargetVascular endothelial growth factor receptor 2(Human)
Institute of Respiratory Health

Curated by ChEMBL
LigandPNGBDBM50021574(CHEBI:72317 | CABOZANTINIB | BMS-907351 | Cometriq...)
Affinity DataIC50: 0.0350nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM50145416(GSK2126458 | Omipalisib)
Affinity DataIC50: 0.0400nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM50642136(CHEMBL5562761)
Affinity DataIC50: 0.100nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Institute of Respiratory Health

Curated by ChEMBL
LigandPNGBDBM50146163(CHEMBL3764045)
Affinity DataIC50: 0.810nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Institute of Respiratory Health

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetVascular endothelial growth factor receptor 2(Human)
Institute of Respiratory Health

Curated by ChEMBL
LigandPNGBDBM734434(US20250129067, Compound Anlotinib)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Institute of Respiratory Health

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 1.20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHepatocyte growth factor receptor(Human)
Institute of Respiratory Health

Curated by ChEMBL
LigandPNGBDBM50021574(CHEBI:72317 | CABOZANTINIB | BMS-907351 | Cometriq...)
Affinity DataIC50: 1.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Institute of Respiratory Health

Curated by ChEMBL
LigandPNGBDBM50279080(methyl (3Z)-3-{[(4-{methyl[(4-methylpiperazin-1-yl...)
Affinity DataIC50: 1.80nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM50642133(CHEMBL5565411)
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Institute of Respiratory Health

Curated by ChEMBL
LigandPNGBDBM50332294(N-tert-butyl-3-(5-methyl-2-(4-(2-(pyrrolidin-1-yl)...)
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetVascular endothelial growth factor receptor 2(Human)
Institute of Respiratory Health

Curated by ChEMBL
LigandPNGBDBM50279080(methyl (3Z)-3-{[(4-{methyl[(4-methylpiperazin-1-yl...)
Affinity DataIC50: 3.10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMast/stem cell growth factor receptor Kit(Human)
Institute of Respiratory Health

Curated by ChEMBL
LigandPNGBDBM50021574(CHEBI:72317 | CABOZANTINIB | BMS-907351 | Cometriq...)
Affinity DataIC50: 4.60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM50642134(CHEMBL1234114)
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Institute of Respiratory Health

Curated by ChEMBL
LigandPNGBDBM50021574(CHEBI:72317 | CABOZANTINIB | BMS-907351 | Cometriq...)
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Institute of Respiratory Health

Curated by ChEMBL
LigandPNGBDBM50642136(CHEMBL5562761)
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Institute of Respiratory Health

Curated by ChEMBL
LigandPNGBDBM50146163(CHEMBL3764045)
Affinity DataIC50: 7.10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDiscoidin domain-containing receptor 2(Human)
Institute of Respiratory Health

Curated by ChEMBL
LigandPNGBDBM50642132(CHEMBL5574484)
Affinity DataIC50: 8.20nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM50642135(CHEMBL5571102)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpithelial discoidin domain-containing receptor 1(Human)
Institute of Respiratory Health

Curated by ChEMBL
LigandPNGBDBM50297825(5-[(2-methyl-5-{[3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataIC50: 12nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDiscoidin domain-containing receptor 2(Human)
Institute of Respiratory Health

Curated by ChEMBL
LigandPNGBDBM50297825(5-[(2-methyl-5-{[3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataIC50: 19nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Institute of Respiratory Health

Curated by ChEMBL
LigandPNGBDBM50642130(CHEMBL5592453)
Affinity DataIC50: 25nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Institute of Respiratory Health

Curated by ChEMBL
LigandPNGBDBM50642131(CHEMBL5591364)
Affinity DataIC50: 31nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetfMet-Leu-Phe receptor(Human)
Institute of Respiratory Health

Curated by ChEMBL
LigandPNGBDBM523339(US11136296, Example 70)
Affinity DataIC50: 32nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Institute of Respiratory Health

Curated by ChEMBL
LigandPNGBDBM50642133(CHEMBL5565411)
Affinity DataIC50: 40nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetFibroblast growth factor receptor 1(Human)
Institute of Respiratory Health

Curated by ChEMBL
LigandPNGBDBM50279080(methyl (3Z)-3-{[(4-{methyl[(4-methylpiperazin-1-yl...)
Affinity DataIC50: 41nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Institute of Respiratory Health

Curated by ChEMBL
LigandPNGBDBM50409189(CHEMBL5283402)
Affinity DataIC50: 42nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Institute of Respiratory Health

Curated by ChEMBL
LigandPNGBDBM50642135(CHEMBL5571102)
Affinity DataIC50: 49nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Institute of Respiratory Health

Curated by ChEMBL
LigandPNGBDBM50642134(CHEMBL1234114)
Affinity DataIC50: 76nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Institute of Respiratory Health

Curated by ChEMBL
LigandPNGBDBM50279080(methyl (3Z)-3-{[(4-{methyl[(4-methylpiperazin-1-yl...)
Affinity DataIC50: 85nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Institute of Respiratory Health

Curated by ChEMBL
LigandPNGBDBM50642130(CHEMBL5592453)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Institute of Respiratory Health

Curated by ChEMBL
LigandPNGBDBM50642130(CHEMBL5592453)
Affinity DataIC50: 110nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Institute of Respiratory Health

Curated by ChEMBL
LigandPNGBDBM50642131(CHEMBL5591364)
Affinity DataIC50: 135nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Institute of Respiratory Health

Curated by ChEMBL
LigandPNGBDBM12244(N-(2-chloro-5-methoxyphenyl)-6,7-dimethoxyquinazol...)
Affinity DataIC50: 250nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetFibroblast growth factor receptor 1(Human)
Institute of Respiratory Health

Curated by ChEMBL
LigandPNGBDBM50642130(CHEMBL5592453)
Affinity DataIC50: 1.60E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Institute of Respiratory Health

Curated by ChEMBL
LigandPNGBDBM50409189(CHEMBL5283402)
Affinity DataIC50: 2.17E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Institute of Respiratory Health

Curated by ChEMBL
LigandPNGBDBM50279080(methyl (3Z)-3-{[(4-{methyl[(4-methylpiperazin-1-yl...)
Affinity DataIC50: 2.60E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Institute of Respiratory Health

Curated by ChEMBL
LigandPNGBDBM50396169(CHEMBL1337170)
Affinity DataIC50: 5.10E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Institute of Respiratory Health

Curated by ChEMBL
LigandPNGBDBM50409189(CHEMBL5283402)
Affinity DataIC50: 5.33E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Institute of Respiratory Health

Curated by ChEMBL
LigandPNGBDBM50187686(CHEMBL3828074 | US9670204, 2 2-((2-ethyl-6-(4-(2-(...)
Affinity DataIC50: 1.50E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetType-2 angiotensin II receptor(Human)
Institute of Respiratory Health

Curated by ChEMBL
LigandPNGBDBM50156173(butyl 3-(4-((1H-imidazol-1-yl)methyl)phenyl)-5-iso...)
Affinity DataKi:  0.400nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetType-2 angiotensin II receptor(Human)
Institute of Respiratory Health

Curated by ChEMBL
LigandPNGBDBM50049189(butyl 3-(4-((2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b...)
Affinity DataKi:  2.80nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetType-1 angiotensin II receptor(Human)
Institute of Respiratory Health

Curated by ChEMBL
LigandPNGBDBM50049189(butyl 3-(4-((2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b...)
Affinity DataKi:  3.90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetType-1 angiotensin II receptor(Human)
Institute of Respiratory Health

Curated by ChEMBL
LigandPNGBDBM50156173(butyl 3-(4-((1H-imidazol-1-yl)methyl)phenyl)-5-iso...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed