BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.1M data for 1.3M Compounds and 9.6K Targets. Of those, 1.5M data for 698K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

8 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Optimization of spirocyclic proline tryptophan hydroxylase-1 inhibitors.EBI
Karos Pharmaceuticals
Tryptophan hydroxylase 1 (Tph-1)-targeted bone anabolic agents for osteoporosis.EBI
Nanjing University
Modulation of peripheral serotonin levels by novel tryptophan hydroxylase inhibitors for the potential treatment of functional gastrointestinal disorders.EBI
Lexicon Pharmaceuticals
Structure-Based Design of Xanthine-Imidazopyridines and -Imidazothiazoles as Highly Potent and In Vivo Efficacious Tryptophan Hydroxylase Inhibitors.EBI
Leibniz-Fmp
Structure-Based Design of Xanthine-Benzimidazole Derivatives as Novel and Potent Tryptophan Hydroxylase Inhibitors.EBI
Leibniz-Forschungsinstitut F�R Molekulare Pharmakologie (Fmp)
1H-pyrazolo[4,3-b]pyridines as PDE1 inhibitorsBDB
H. Lundbeck
(S)-5-ethynyl-anabasine, derivatives thereof, and related compositions and methods of making and usingBDB
Iowa State University Research Foundation
Quinuclidine derivatives and medicinal compositions containing the sameBDB
Almirall