33 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Design and synthesis of novel 2-substituted 11-keto-boswellic acid heterocyclic derivatives as anti-prostate cancer agents with Pin1 inhibition ability.
Shenyang Pharmaceutical University
Peptidyl prolyl isomerase Pin1-inhibitory activity of D-glutamic and D-aspartic acid derivatives bearing a cyclic aliphatic amine moiety.
Nagoya City University
A Selective, Cell-Permeable Nonphosphorylated Bicyclic Peptidyl Inhibitor against Peptidyl-Prolyl Isomerase Pin1.
The Ohio State University
Structure-based design of novel human Pin1 inhibitors (III): optimizing affinity beyond the phosphate recognition pocket.
Pfizer
Synthesis of the novel elemonic acid derivatives as Pin1 inhibitors.
Shenyang Pharmaceutical University
Synthesis and biological evaluation of novel human Pin1 inhibitors with benzophenone skeleton.
Peking Union Medical College
Discovery and characterization of a nonphosphorylated cyclic peptide inhibitor of the peptidylprolyl isomerase, Pin1.
The University of Western Ontario
Synthesis and biological evaluation of novel quinazoline-derived human Pin1 inhibitors.
Peking Union Medical College
Discovery of cell-active phenyl-imidazole Pin1 inhibitors by structure-guided fragment evolution.
Vernalis (R&D)
Biological Function of Pin1 in Vivo and Its Inhibitors for Preclinical Study: Early Development, Current Strategies, and Future Directions.
Shanghai University
Peptidyl-Proline Isomerases (PPIases): Targets for Natural Products and Natural Product-Inspired Compounds.
University of Michigan
Nanomolar inhibitors of the peptidyl prolyl cis/trans isomerase Pin1 from combinatorial peptide libraries.
Max Planck Research Unit For Enzymology of Protein Folding
Control of protein-protein interactions: structure-based discovery of low molecular weight inhibitors of the interactions between Pin1 WW domain and phosphopeptides.
Cnrs-University of Lille 2 Umr 8525
Triazine-Based Covalent DNA-Encoded Libraries for Discovery of Covalent Inhibitors of Target Proteins.
Chinese Academy of Sciences
Computational and Structure-Based Development of High Potent Cell-Active Covalent Inhibitor Targeting the Peptidyl-Prolyl Isomerase NIMA-Interacting-1 (Pin1).
Chinese Academy of Sciences
Targeting Protein Folding: A Novel Approach for the Treatment of Pathogenic Bacteria.
University of W£Rzburg
A Phosphoramidate Strategy Enables Membrane Permeability of a Non-nucleotide Inhibitor of the Prolyl Isomerase Pin1.
University of California San Francisco
Synthesis and Pin1 inhibitory activity of thiazole derivatives.
Peking Union Medical College
Design, synthesis and biological evaluation of novel thiazole-based derivatives as human Pin1 inhibitors.
Peking Union Medical College
Synthesis and cytotoxic evaluation of cycloheximide derivatives as potential inhibitors of FKBP12 with neuroregenerative properties.
Max-Planck Research Unit
Design, synthesis and biological evaluation of benzimidazole derivatives as novel human Pin1 inhibitors.
Shenyang Pharmaceutical University
An irreversible inhibitor of peptidyl-prolyl cis/trans isomerase Pin1 and evaluation of cytotoxicity.
Nagoya Citi University
Discovery of 4,6-bis(benzyloxy)-3-phenylbenzofuran as a novel Pin1 inhibitor to suppress hepatocellular carcinoma via upregulating microRNA biogenesis.
Sichuan University
Membrane permeable cyclic peptidyl inhibitors against human Peptidylprolyl Isomerase Pin1.
The Ohio State University
Design, synthesis and biological evaluation of ring A modified 11-keto-boswellic acid derivatives as Pin1 inhibitors with remarkable anti-prostate cancer activity.
Shenyang Pharmaceutical University
Synthesis and biological evaluation of pyrimidine derivatives as novel human Pin1 inhibitors.
Peking Union Medical College
Conjugates of 18β-glycyrrhetinic acid derivatives with 3-(1H-benzo[d]imidazol-2-yl)propanoic acid as Pin1 inhibitors displaying anti-prostate cancer ability.
Shenyang Pharmaceutical University
Benzimidazole-2-piperazine heterocyclic compound, pharmaceutical composition containing the same, preparation method and use thereof
Shanghai Huilun Life Science & Technology