BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.1M data for 1.3M Compounds and 9.6K Targets. Of those, 1.5M data for 698K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

16 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Human Toll-like receptor 8-selective agonistic activities in 1-alkyl-1H-benzimidazol-2-amines.EBI
University of Kansas
Nucleotide-binding oligomerization domain (NOD) inhibitors: a rational approach toward inhibition of NOD signaling pathway.EBI
University of Ljubljana
Identification of Inhibitors of NOD1-Induced Nuclear Factor-¿B Activation.EBI
TBA
Structure-activity relationships in nucleotide oligomerization domain 1 (Nod1) agonistic¿-glutamyldiaminopimelic acid derivatives.EBI
University of Kansas
Salutaxel, a Conjugate of Docetaxel and a Muramyl Dipeptide (MDP) Analogue, Acts as Multifunctional Prodrug That Inhibits Tumor Growth and Metastasis.EBI
Shenzhen Salubris Pharmaceuticals Co.
Identification of benzofused five-membered sultams, potent dual NOD1/NOD2 antagonists in vitro and in vivo.EBI
Peking Union Medical College
Structural features and functional activities of benzimidazoles as NOD2 antagonists.EBI
University of Ljubljana
Nonpeptidic quinazolinone derivatives as dual nucleotide-binding oligomerization domain-like receptor 1/2 antagonists for adjuvant cancer chemotherapy.EBI
Peking Union Medical College
Identification of indole scaffold-based dual inhibitors of NOD1 and NOD2.EBI
University of Ljubljana
Modulation of the NOD-like receptors NOD1 and NOD2: A chemist's perspective.EBI
University of Delaware
Discovery of 1,4-Benzodiazepine-2,5-dione (BZD) Derivatives as Dual Nucleotide Binding Oligomerization Domain Containing 1/2 (NOD1/NOD2) Antagonists Sensitizing Paclitaxel (PTX) To Suppress Lewis Lung Carcinoma (LLC) Growth in Vivo.EBI
Peking Union Medical College
Methods for treating pulmonary emphysema using substituted 2-Aza-bicyclo[2.2.1]heptane-3-carboxylic acid (benzyl-cyano-methyl)-amides inhibitors of Cathepsin CBDB
Boehringer Ingelheim International
Heteroaromatic compounds and their use as dopamine D1 ligandsBDB
Pfizer
2-Amino-N-pyrimidin-4-ylacetamides as A2A Receptor Antagonists: 2. Reduction of hERG Activity, Observed Species Selectivity, and Structure-Activity Relationships.BDB
Neuroscience
7'-substituted benzothiazolothio- and pyridinothiazolothio-purines as potent heat shock protein 90 inhibitors.BDB
Conforma Therapeutics
Discovery of substituted maleimides as liver X receptor agonists and determination of a ligand-bound crystal structure.BDB
Glaxosmithkline