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BindingDB contains 3.1M data for 1.3M Compounds and 9.6K Targets. Of those, 1.5M data for 698K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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11 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Evaluation of known and novel inhibitors of Orai1-mediated store operated CaEBI
The University of Queensland
Discovery of 7-azaindole derivatives as potent Orai inhibitors showing efficacy in a preclinical model of asthma.EBI
RhôNe-Poulenc Rorer
Review of Transient Receptor Potential Canonical (TRPC5) Channel Modulators and Diseases.EBI
University of Nebraska Medical Center
An SAR study of hydroxy-trifluoromethylpyrazolines as inhibitors of Orai1-mediated store operated CaEBI
University of Auckland
CD73 COMPOUNDSBDB
Gilead Sciences
Compounds and methods for inhibiting JAKBDB
Dizal (Jiangsu) Pharmaceutical
Design, synthesis, and X-ray crystal structures of 2,4-diaminofuro[2,3-d]pyrimidines as multireceptor tyrosine kinase and dihydrofolate reductase inhibitors.BDB
Duquesne University
Discovery of begacestat, a Notch-1-sparing gamma-secretase inhibitor for the treatment of Alzheimer's disease.BDB
Wyeth Research
Design and synthesis of 2-amino-pyrazolopyridines as Polo-like kinase 1 inhibitors.BDB
Sunesis Pharmaceuticals
Inhibitors of the tyrosine kinase EphB4. Part 1: Structure-based design and optimization of a series of 2,4-bis-anilinopyrimidines.BDB
Astrazeneca