Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 2846
TargetEphrin type-B receptor 4(Human)
Astrazeneca

LigandPNGBDBM25223(3-({4-[(5-chloro-2H-1,3-benzodioxol-4-yl)amino]pyr...)
Affinity DataIC50: 40nMpH: 7.4 T: 2°CAssay Description:This assay detects inhibitors of EphB4-mediated phosphorylation of a polypeptide substrate using Alphascreen luminescence detection technology. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEphrin type-B receptor 4(Human)
Astrazeneca

LigandPNGBDBM25226(4-N-(5-chloro-2H-1,3-benzodioxol-4-yl)-2-N-(3-meth...)
Affinity DataIC50: 90nMpH: 7.4 T: 2°CAssay Description:This assay detects inhibitors of EphB4-mediated phosphorylation of a polypeptide substrate using Alphascreen luminescence detection technology. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEphrin type-B receptor 4(Human)
Astrazeneca

LigandPNGBDBM25205(4-N-(5-chloro-2H-1,3-benzodioxol-4-yl)-2-N-(3,4,5-...)
Affinity DataIC50: 240nMpH: 7.4 T: 2°CAssay Description:This assay detects inhibitors of EphB4-mediated phosphorylation of a polypeptide substrate using Alphascreen luminescence detection technology. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEphrin type-B receptor 4(Human)
Astrazeneca

LigandPNGBDBM25224(4-({4-[(5-chloro-2H-1,3-benzodioxol-4-yl)amino]pyr...)
Affinity DataIC50: 300nMpH: 7.4 T: 2°CAssay Description:This assay detects inhibitors of EphB4-mediated phosphorylation of a polypeptide substrate using Alphascreen luminescence detection technology. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

LigandPNGBDBM6219(BMCL182776 Compound 1 | N-(5-chloro-2H-1,3-benzodi...)
Affinity DataIC50: 350nMpH: 7.4 T: 2°CAssay Description:This assay detects inhibitors of EphB4-mediated phosphorylation of a polypeptide substrate using Alphascreen luminescence detection technology. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEphrin type-B receptor 4(Human)
Astrazeneca

LigandPNGBDBM25214(4-N-(5-chloro-2H-1,3-benzodioxol-4-yl)-2-N-(3-meth...)
Affinity DataIC50: 460nMpH: 7.4 T: 2°CAssay Description:This assay detects inhibitors of EphB4-mediated phosphorylation of a polypeptide substrate using Alphascreen luminescence detection technology. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

LigandPNGBDBM25220(3-({4-[(5-chloro-2H-1,3-benzodioxol-4-yl)amino]pyr...)
Affinity DataIC50: 550nMpH: 7.4 T: 2°CAssay Description:This assay detects inhibitors of EphB4-mediated phosphorylation of a polypeptide substrate using Alphascreen luminescence detection technology. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

LigandPNGBDBM25229(4-N-(5-chloro-2H-1,3-benzodioxol-4-yl)-2-N-[3-(mor...)
Affinity DataIC50: 580nMpH: 7.4 T: 2°CAssay Description:This assay detects inhibitors of EphB4-mediated phosphorylation of a polypeptide substrate using Alphascreen luminescence detection technology. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEphrin type-B receptor 4(Human)
Astrazeneca

LigandPNGBDBM25227(4-N-(5-chloro-2H-1,3-benzodioxol-4-yl)-2-N-(4-meth...)
Affinity DataIC50: 630nMpH: 7.4 T: 2°CAssay Description:This assay detects inhibitors of EphB4-mediated phosphorylation of a polypeptide substrate using Alphascreen luminescence detection technology. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

LigandPNGBDBM25217(4-N-(5-chloro-2H-1,3-benzodioxol-4-yl)-2-N-(3-meth...)
Affinity DataIC50: 640nMpH: 7.4 T: 2°CAssay Description:This assay detects inhibitors of EphB4-mediated phosphorylation of a polypeptide substrate using Alphascreen luminescence detection technology. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

LigandPNGBDBM25230(4-N-(5-chloro-2H-1,3-benzodioxol-4-yl)-2-N-[4-(mor...)
Affinity DataIC50: 1.00E+3nMpH: 7.4 T: 2°CAssay Description:This assay detects inhibitors of EphB4-mediated phosphorylation of a polypeptide substrate using Alphascreen luminescence detection technology. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

LigandPNGBDBM25208(4-N-(5-chloro-2H-1,3-benzodioxol-4-yl)-2-N-(3-fluo...)
Affinity DataIC50: 1.15E+3nMpH: 7.4 T: 2°CAssay Description:This assay detects inhibitors of EphB4-mediated phosphorylation of a polypeptide substrate using Alphascreen luminescence detection technology. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

LigandPNGBDBM25221(4-({4-[(5-chloro-2H-1,3-benzodioxol-4-yl)amino]pyr...)
Affinity DataIC50: 1.25E+3nMpH: 7.4 T: 2°CAssay Description:This assay detects inhibitors of EphB4-mediated phosphorylation of a polypeptide substrate using Alphascreen luminescence detection technology. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

LigandPNGBDBM25211(4-N-(5-chloro-2H-1,3-benzodioxol-4-yl)-2-N-(3-chlo...)
Affinity DataIC50: 1.33E+3nMpH: 7.4 T: 2°CAssay Description:This assay detects inhibitors of EphB4-mediated phosphorylation of a polypeptide substrate using Alphascreen luminescence detection technology. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

LigandPNGBDBM25206(4-N-(5-chloro-2H-1,3-benzodioxol-4-yl)-2-N-phenylp...)
Affinity DataIC50: 1.55E+3nMpH: 7.4 T: 2°CAssay Description:This assay detects inhibitors of EphB4-mediated phosphorylation of a polypeptide substrate using Alphascreen luminescence detection technology. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

LigandPNGBDBM25215(4-N-(5-chloro-2H-1,3-benzodioxol-4-yl)-2-N-(4-meth...)
Affinity DataIC50: 1.60E+3nMpH: 7.4 T: 2°CAssay Description:This assay detects inhibitors of EphB4-mediated phosphorylation of a polypeptide substrate using Alphascreen luminescence detection technology. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

LigandPNGBDBM25218(4-N-(5-chloro-2H-1,3-benzodioxol-4-yl)-2-N-(4-meth...)
Affinity DataIC50: 1.94E+3nMpH: 7.4 T: 2°CAssay Description:This assay detects inhibitors of EphB4-mediated phosphorylation of a polypeptide substrate using Alphascreen luminescence detection technology. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

LigandPNGBDBM25209(4-N-(5-chloro-2H-1,3-benzodioxol-4-yl)-2-N-(4-fluo...)
Affinity DataIC50: 2.30E+3nMpH: 7.4 T: 2°CAssay Description:This assay detects inhibitors of EphB4-mediated phosphorylation of a polypeptide substrate using Alphascreen luminescence detection technology. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

LigandPNGBDBM25204(4-N-(5-chloro-2H-1,3-benzodioxol-4-yl)-6-N-(3,4,5-...)
Affinity DataIC50: 2.54E+3nMpH: 7.4 T: 2°CAssay Description:This assay detects inhibitors of EphB4-mediated phosphorylation of a polypeptide substrate using Alphascreen luminescence detection technology. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

LigandPNGBDBM25203(2-N-(5-chloro-2H-1,3-benzodioxol-4-yl)-4-N-(3,4,5-...)
Affinity DataIC50: 2.96E+3nMpH: 7.4 T: 2°CAssay Description:This assay detects inhibitors of EphB4-mediated phosphorylation of a polypeptide substrate using Alphascreen luminescence detection technology. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

LigandPNGBDBM25216(4-N-(5-chloro-2H-1,3-benzodioxol-4-yl)-2-N-(2-meth...)
Affinity DataIC50: 3.88E+3nMpH: 7.4 T: 2°CAssay Description:This assay detects inhibitors of EphB4-mediated phosphorylation of a polypeptide substrate using Alphascreen luminescence detection technology. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

LigandPNGBDBM25207(4-N-(5-chloro-2H-1,3-benzodioxol-4-yl)-2-N-(2-fluo...)
Affinity DataIC50: 5.00E+3nMpH: 7.4 T: 2°CAssay Description:This assay detects inhibitors of EphB4-mediated phosphorylation of a polypeptide substrate using Alphascreen luminescence detection technology. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

LigandPNGBDBM25212(4-N-(5-chloro-2H-1,3-benzodioxol-4-yl)-2-N-(4-chlo...)
Affinity DataIC50: 6.00E+3nMpH: 7.4 T: 2°CAssay Description:This assay detects inhibitors of EphB4-mediated phosphorylation of a polypeptide substrate using Alphascreen luminescence detection technology. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

LigandPNGBDBM25228(4-N-(5-chloro-2H-1,3-benzodioxol-4-yl)-2-N-[2-(mor...)
Affinity DataIC50: 7.85E+3nMpH: 7.4 T: 2°CAssay Description:This assay detects inhibitors of EphB4-mediated phosphorylation of a polypeptide substrate using Alphascreen luminescence detection technology. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

LigandPNGBDBM25210(4-N-(5-chloro-2H-1,3-benzodioxol-4-yl)-2-N-(2-chlo...)
Affinity DataIC50: 1.13E+4nMpH: 7.4 T: 2°CAssay Description:This assay detects inhibitors of EphB4-mediated phosphorylation of a polypeptide substrate using Alphascreen luminescence detection technology. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

LigandPNGBDBM25213(4-N-(5-chloro-2H-1,3-benzodioxol-4-yl)-2-N-(2-meth...)
Affinity DataIC50: 1.40E+4nMpH: 7.4 T: 2°CAssay Description:This assay detects inhibitors of EphB4-mediated phosphorylation of a polypeptide substrate using Alphascreen luminescence detection technology. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

LigandPNGBDBM25202(2-N-(3-chloro-4-methoxyphenyl)-4-N-(3,4,5-trimetho...)
Affinity DataIC50: 1.60E+4nMpH: 7.4 T: 2°CAssay Description:This assay detects inhibitors of EphB4-mediated phosphorylation of a polypeptide substrate using Alphascreen luminescence detection technology. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEphrin type-B receptor 4(Human)
Astrazeneca

LigandPNGBDBM25219(2-({4-[(5-chloro-2H-1,3-benzodioxol-4-yl)amino]pyr...)
Affinity DataIC50: 2.05E+4nMpH: 7.4 T: 2°CAssay Description:This assay detects inhibitors of EphB4-mediated phosphorylation of a polypeptide substrate using Alphascreen luminescence detection technology. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

LigandPNGBDBM25222(2-({4-[(5-chloro-2H-1,3-benzodioxol-4-yl)amino]pyr...)
Affinity DataIC50: 3.55E+4nMpH: 7.4 T: 2°CAssay Description:This assay detects inhibitors of EphB4-mediated phosphorylation of a polypeptide substrate using Alphascreen luminescence detection technology. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

LigandPNGBDBM25225(4-N-(5-chloro-2H-1,3-benzodioxol-4-yl)-2-N-(2-meth...)
Affinity DataIC50: 4.10E+4nMpH: 7.4 T: 2°CAssay Description:This assay detects inhibitors of EphB4-mediated phosphorylation of a polypeptide substrate using Alphascreen luminescence detection technology. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed