Compile Data Set for Download or QSAR
Report error Found 115 Enz. Inhib. hit(s) with all data for entry = 3423
TargetEpidermal growth factor receptor(Human)
Duquesne University

LigandPNGBDBM3032(CHEMBL29197 | N-(3-bromophenyl)-6,7-dimethoxyquina...)
Affinity DataIC50: 200nMpH: 7.4 T: 2°CAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Duquesne University

LigandPNGBDBM33395(Z-isomer | 2,4-diaminofuro[2,3-d]pyrimidine, 1b)
Affinity DataIC50: 1.90E+3nMAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Duquesne University

LigandPNGBDBM33402(2,4-diaminofuro[2,3-d]pyrimidine, 8)
Affinity DataIC50: 2.20E+3nMpH: 7.4 T: 2°CAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Duquesne University

LigandPNGBDBM4810(cid_5329098 | CHEMBL276711 | SU5146 | (3Z)-3-[(3,5...)
Affinity DataIC50: 2.40E+3nMpH: 7.4 T: 2°CAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Duquesne University

LigandPNGBDBM33403(2,4-diaminofuro[2,3-d]pyrimidine, 9)
Affinity DataIC50: 3.20E+3nMAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Duquesne University

LigandPNGBDBM33404(2,4-diaminofuro[2,3-d]pyrimidine, 10)
Affinity DataIC50: 3.70E+3nMAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Duquesne University

LigandPNGBDBM33395(Z-isomer | 2,4-diaminofuro[2,3-d]pyrimidine, 1b)
Affinity DataIC50: 3.90E+3nMAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

LigandPNGBDBM33395(Z-isomer | 2,4-diaminofuro[2,3-d]pyrimidine, 1b)
Affinity DataIC50: 3.94E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

LigandPNGBDBM33394(E-isomer | 2,4-diaminofuro[2,3-d]pyrimidine, 1a)
Affinity DataIC50: 4.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Duquesne University

LigandPNGBDBM33397(E/Z ratio=3:1 | 2,4-diaminofuro[2,3-d]pyrimidine, ...)
Affinity DataIC50: 4.14E+3nMAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydrofolate reductase(Mouse)
Duquesne University

LigandPNGBDBM33401(E/Z ratio=3:2 | 2,4-diaminofuro[2,3-d]pyrimidine, ...)
Affinity DataIC50: 4.20E+3nMAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

LigandPNGBDBM33404(2,4-diaminofuro[2,3-d]pyrimidine, 10)
Affinity DataIC50: 4.44E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

LigandPNGBDBM33398(E/Z ratio=2:1 | 2,4-diaminofuro[2,3-d]pyrimidine, ...)
Affinity DataIC50: 4.60E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Duquesne University

LigandPNGBDBM33398(E/Z ratio=2:1 | 2,4-diaminofuro[2,3-d]pyrimidine, ...)
Affinity DataIC50: 4.64E+3nMAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Duquesne University

LigandPNGBDBM33403(2,4-diaminofuro[2,3-d]pyrimidine, 9)
Affinity DataIC50: 5.00E+3nMAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Duquesne University

LigandPNGBDBM33404(2,4-diaminofuro[2,3-d]pyrimidine, 10)
Affinity DataIC50: 5.01E+3nMAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Duquesne University

LigandPNGBDBM33403(2,4-diaminofuro[2,3-d]pyrimidine, 9)
Affinity DataIC50: 5.09E+3nMAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

LigandPNGBDBM33401(E/Z ratio=3:2 | 2,4-diaminofuro[2,3-d]pyrimidine, ...)
Affinity DataIC50: 5.70E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Duquesne University

LigandPNGBDBM33408(cid_2048 | CHEMBL7724 | AG1295)
Affinity DataIC50: 6.20E+3nMAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Duquesne University

LigandPNGBDBM33397(E/Z ratio=3:1 | 2,4-diaminofuro[2,3-d]pyrimidine, ...)
Affinity DataIC50: 6.35E+3nMAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

LigandPNGBDBM33403(2,4-diaminofuro[2,3-d]pyrimidine, 9)
Affinity DataIC50: 7.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

LigandPNGBDBM33397(E/Z ratio=3:1 | 2,4-diaminofuro[2,3-d]pyrimidine, ...)
Affinity DataIC50: 7.50E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Duquesne University

LigandPNGBDBM33396(E/Z ratio=2:1 | 2,4-diaminofuro[2,3-d]pyrimidine, ...)
Affinity DataIC50: 7.92E+3nMAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Duquesne University

LigandPNGBDBM33401(E/Z ratio=3:2 | 2,4-diaminofuro[2,3-d]pyrimidine, ...)
Affinity DataIC50: 8.64E+3nMAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

LigandPNGBDBM33401(E/Z ratio=3:2 | 2,4-diaminofuro[2,3-d]pyrimidine, ...)
Affinity DataIC50: 9.64E+3nMAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

LigandPNGBDBM33404(2,4-diaminofuro[2,3-d]pyrimidine, 10)
Affinity DataIC50: 1.01E+4nMAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

LigandPNGBDBM33395(Z-isomer | 2,4-diaminofuro[2,3-d]pyrimidine, 1b)
Affinity DataIC50: 1.02E+4nMAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydrofolate reductase(Human)
Duquesne University

LigandPNGBDBM33398(E/Z ratio=2:1 | 2,4-diaminofuro[2,3-d]pyrimidine, ...)
Affinity DataIC50: 1.02E+4nMAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Duquesne University

LigandPNGBDBM33394(E-isomer | 2,4-diaminofuro[2,3-d]pyrimidine, 1a)
Affinity DataIC50: 1.03E+4nMAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

LigandPNGBDBM33398(E/Z ratio=2:1 | 2,4-diaminofuro[2,3-d]pyrimidine, ...)
Affinity DataIC50: 1.03E+4nMAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

LigandPNGBDBM33396(E/Z ratio=2:1 | 2,4-diaminofuro[2,3-d]pyrimidine, ...)
Affinity DataIC50: 1.18E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

LigandPNGBDBM33397(E/Z ratio=3:1 | 2,4-diaminofuro[2,3-d]pyrimidine, ...)
Affinity DataIC50: 1.19E+4nMAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydrofolate reductase(Human)
Duquesne University

LigandPNGBDBM33396(E/Z ratio=2:1 | 2,4-diaminofuro[2,3-d]pyrimidine, ...)
Affinity DataIC50: 1.22E+4nMAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

LigandPNGBDBM33404(2,4-diaminofuro[2,3-d]pyrimidine, 10)
Affinity DataIC50: 1.25E+4nMAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

LigandPNGBDBM33403(2,4-diaminofuro[2,3-d]pyrimidine, 9)
Affinity DataIC50: 1.26E+4nMAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Duquesne University

LigandPNGBDBM33394(E-isomer | 2,4-diaminofuro[2,3-d]pyrimidine, 1a)
Affinity DataIC50: 1.28E+4nMpH: 7.4 T: 2°CAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Duquesne University

LigandPNGBDBM33405(2,4-diaminofuro[2,3-d]pyrimidine, 11)
Affinity DataIC50: 1.34E+4nMpH: 7.4 T: 2°CAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Duquesne University

LigandPNGBDBM33404(2,4-diaminofuro[2,3-d]pyrimidine, 10)
Affinity DataIC50: 1.37E+4nMAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Duquesne University

LigandPNGBDBM33394(E-isomer | 2,4-diaminofuro[2,3-d]pyrimidine, 1a)
Affinity DataIC50: 1.45E+4nMAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

LigandPNGBDBM33396(E/Z ratio=2:1 | 2,4-diaminofuro[2,3-d]pyrimidine, ...)
Affinity DataIC50: 1.52E+4nMAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

LigandPNGBDBM33407(2,4-diaminofuro[2,3-d]pyrimidine, 13)
Affinity DataIC50: 1.54E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Duquesne University

LigandPNGBDBM33394(E-isomer | 2,4-diaminofuro[2,3-d]pyrimidine, 1a)
Affinity DataIC50: 1.64E+4nMAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Duquesne University

LigandPNGBDBM33407(2,4-diaminofuro[2,3-d]pyrimidine, 13)
Affinity DataIC50: 1.74E+4nMpH: 7.4 T: 2°CAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Duquesne University

LigandPNGBDBM33396(E/Z ratio=2:1 | 2,4-diaminofuro[2,3-d]pyrimidine, ...)
Affinity DataIC50: 1.78E+4nMAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Duquesne University

LigandPNGBDBM33403(2,4-diaminofuro[2,3-d]pyrimidine, 9)
Affinity DataIC50: 1.82E+4nMpH: 7.4 T: 2°CAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

LigandPNGBDBM33394(E-isomer | 2,4-diaminofuro[2,3-d]pyrimidine, 1a)
Affinity DataIC50: 1.85E+4nMAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

LigandPNGBDBM33405(2,4-diaminofuro[2,3-d]pyrimidine, 11)
Affinity DataIC50: 1.96E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

LigandPNGBDBM33406(2,4-diaminofuro[2,3-d]pyrimidine, 12)
Affinity DataIC50: 2.22E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

LigandPNGBDBM33398(E/Z ratio=2:1 | 2,4-diaminofuro[2,3-d]pyrimidine, ...)
Affinity DataIC50: 2.22E+4nMAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

LigandPNGBDBM33400(E/Z ratio=2:1 | 2,4-diaminofuro[2,3-d]pyrimidine, ...)
Affinity DataIC50: 2.49E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
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