41 articles for thisTarget
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Biology-oriented drug synthesis (BIODS): In vitroß-glucuronidase inhibitory and in silico studies on 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl aryl carboxylate derivatives.
University of Karachi
Synthesis and biological evaluation of novel N-arylidenequinoline-3-carbohydrazides as potentß-glucuronidase inhibitors.
Universiti Teknologi Mara (Uitm)
Thiadiazole derivatives as New Class ofß-glucuronidase inhibitors.
University of Karachi
Synthesis of novel benzohydrazone-oxadiazole hybrids asß-glucuronidase inhibitors and molecular modeling studies.
Universiti Teknologi Mara (Uitm)
Novel 2,5-disubtituted-1,3,4-oxadiazoles with benzimidazole backbone: a new class ofß-glucuronidase inhibitors and in silico studies.
Universiti Teknologi Mara
Substituted thieno[2,3-b]thiophenes and related congeners: Synthesis,ß-glucuronidase inhibition activity, crystal structure, and POM analyses.
King Saud University
Synthesis andß-glucuronidase inhibitory activity of 2-arylquinazolin-4(3H)-ones.
University of Karachi
Evaluation of bisindole as potentß-glucuronidase inhibitors: synthesis and in silico based studies.
University of Karachi
Anti-inflammatory flavonoids and pterocarpanoid from Crotalaria pallida and C. assamica.
Kaohsiung Medical University
Structure-based lead optimization to improve potency and selectivity of a novel tetrahydroimidazo[1,2-a]pyridine-5-carboxylic acid series of heparanase-1 inhibitor.
Taisho Pharmaceutical
Exploring gabosine and chlorogentisyl alcohol derivatives from a marine-derived fungus as EcGUS inhibitors with informatic assisted approaches.
Zhejiang University
Nanomolar β-glucosidase and β-galactosidase inhibition by enantiomeric α-1-C-alkyl-1,4-dideoxy-1,4-imino-arabinitol derivatives.
Chinese Academy of Sciences
Lead identification of novel tetrahydroimidazo[1,2-a]pyridine-5-carboxylic acid derivative as a potent heparanase-1 inhibitor.
Taisho Pharmaceutical Co.
Synthesis and glycosidase inhibition of 5-C-alkyl-DNJ and 5-C-alkyl-l-ido-DNJ derivatives.
Chinese Academy of Sciences
Metronidazole-conjugates: A comprehensive review of recent developments towards synthesis and medicinal perspective.
North-West University
One-pot synthesis of thioxo-tetrahydropyrimidine derivatives as potent β-glucuronidase inhibitor, biological evaluation, molecular docking and molecular dynamics studies.
Shiraz University of Medical Sciences
Therapeutic significance of β-glucuronidase activity and its inhibitors: A review.
University of Kwazulu-Natal
Isolation and Structural Characterization of Specific Bacterial β-Glucuronidase Inhibitors from Noni (
Wayne State University
Synthetic approaches and pharmaceutical applications of chloro-containing molecules for drug discovery: A critical review.
Wuhan University of Technology
Substituent Position of Iminocyclitols Determines the Potency and Selectivity for Gut Microbial Xenobiotic-Reactivating Enzymes.
Academia Sinica
Synthesis of oxadiazole-coupled-thiadiazole derivatives as a potent β-glucuronidase inhibitors and their molecular docking study.
Imam Abdulrahman Bin Faisal University
Synthesis of novel inhibitors of β-glucuronidase based on benzothiazole skeleton and study of their binding affinity by molecular docking.
University of Karachi
Scoparic acid A, a beta-glucuronidase inhibitor from Scoparia dulcis.
Toyama Medical and Pharmaceutical University
Synthesis of bis-indolylmethanes as new potential inhibitors of β-glucuronidase and their molecular docking studies.
Imam Abdulrahman Bin Faisal University
Synthesis, in vitro β-glucuronidase inhibitory potential and molecular docking studies of quinolines.
University of Karachi
Small molecule DCN1 inhibitors and therapeutic methods using the same
University Of Michigan
Investigating the Reaction Mechanism of F420-Dependent Glucose-6-phosphate Dehydrogenase from Mycobacterium tuberculosis: Kinetic Analysis of the Wild-Type and Mutant Enzymes.
The University of Texas At Arlington
Synthesis, molecular docking, and biological evaluation of some novel hydrazones and pyrazole derivatives as anti-inflammatory agents.
Cairo University
Evaluating the Role of Macrocycles in the Susceptibility of Hepatitis C Virus NS3/4A Protease Inhibitors to Drug Resistance.
University of Massachusetts Medical School
Synthesis and urease enzyme inhibitory effects of some dicoumarols.
University of Karachi
Characterization of LY344864 as a pharmacological tool to study 5-HT1F receptors: binding affinities, brain penetration and activity in the neurogenic dural inflammation model of migraine.
Eli Lilly