Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 50013686
TargetCarbonic anhydrase 2(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50568585(CHEMBL4876707)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 preincubated with enzyme for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 preincubated with enzyme for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 9(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataIC50: 28nMAssay Description:Inhibition of recombinant human carbonic anhydrase 9 preincubated with enzyme for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50568588(CHEMBL4878420)
Affinity DataIC50: 33nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 preincubated with enzyme for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50568586(CHEMBL4859439)
Affinity DataIC50: 38nMAssay Description:Inhibition of recombinant human carbonic anhydrase 9 preincubated with enzyme for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50568587(CHEMBL4870827)
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 preincubated with enzyme for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50568586(CHEMBL4859439)
Affinity DataIC50: 89nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 preincubated with enzyme for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50568585(CHEMBL4876707)
Affinity DataIC50: 93nMAssay Description:Inhibition of recombinant human carbonic anhydrase 9 preincubated with enzyme for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50568588(CHEMBL4878420)
Affinity DataIC50: 112nMAssay Description:Inhibition of recombinant human carbonic anhydrase 9 preincubated with enzyme for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50568587(CHEMBL4870827)
Affinity DataIC50: 135nMAssay Description:Inhibition of recombinant human carbonic anhydrase 9 preincubated with enzyme for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM10857(aromatic sulfonamide compound 5 | CHEMBL21 | 4-ami...)
Affinity DataIC50: 256nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 preincubated with enzyme for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 9(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM10857(aromatic sulfonamide compound 5 | CHEMBL21 | 4-ami...)
Affinity DataIC50: 298nMAssay Description:Inhibition of recombinant human carbonic anhydrase 9 preincubated with enzyme for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetPancreatic alpha-amylase(Pig)
North-West University

Curated by ChEMBL
LigandPNGBDBM50568592(CHEMBL4861741)
Affinity DataIC50: 380nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using 1% starch as substrate preincubated for 10 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM21(VANDETANIB | N-(4-bromo-2-fluorophenyl)-6-methoxy-...)
Affinity DataIC50: 850nMAssay Description:Inhibition of EGFR in human A-431 cells assessed as antiproliferative activity incubated for 48 hrs by MTS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50568582(CHEMBL4857212)
Affinity DataIC50: 980nMAssay Description:Inhibition of telomerase in human SGC-7901 cell extract by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50515498(CHEMBL4463898)
Affinity DataIC50: 1.64E+3nMAssay Description:Inhibition of EGFR in human A-431 cells assessed as antiproliferative activity incubated for 48 hrs by MTS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetPancreatic alpha-amylase(Pig)
North-West University

Curated by ChEMBL
LigandPNGBDBM50568593(CHEMBL4864128)
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using 1% starch as substrate preincubated for 10 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetPancreatic alpha-amylase(Pig)
North-West University

Curated by ChEMBL
LigandPNGBDBM23406((3R,4R,5S,6R)-5-{[(2R,3R,4R,5S,6R)-5-{[(2R,3R,4S,5...)
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using 1% starch as substrate preincubated for 10 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50568583(CHEMBL4852832)
Affinity DataIC50: 1.92E+3nMAssay Description:Inhibition of telomerase in human SGC-7901 cell extract by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetPancreatic alpha-amylase(Pig)
North-West University

Curated by ChEMBL
LigandPNGBDBM50568608(CHEMBL4867711)
Affinity DataIC50: 2.98E+3nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using 1% starch as substrate preincubated for 10 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetPancreatic alpha-amylase(Pig)
North-West University

Curated by ChEMBL
LigandPNGBDBM50568607(CHEMBL4859605)
Affinity DataIC50: 2.98E+3nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using 1% starch as substrate preincubated for 10 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetPancreatic alpha-amylase(Pig)
North-West University

Curated by ChEMBL
LigandPNGBDBM50568606(CHEMBL4859800)
Affinity DataIC50: 2.98E+3nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using 1% starch as substrate preincubated for 10 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetPancreatic alpha-amylase(Pig)
North-West University

Curated by ChEMBL
LigandPNGBDBM50568605(CHEMBL4876278)
Affinity DataIC50: 2.98E+3nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using 1% starch as substrate preincubated for 10 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetPancreatic alpha-amylase(Pig)
North-West University

Curated by ChEMBL
LigandPNGBDBM50568609(CHEMBL4866166)
Affinity DataIC50: 2.98E+3nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using 1% starch as substrate preincubated for 10 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetPancreatic alpha-amylase(Pig)
North-West University

Curated by ChEMBL
LigandPNGBDBM50568610(CHEMBL4866437)
Affinity DataIC50: 2.98E+3nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using 1% starch as substrate preincubated for 10 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetPancreatic alpha-amylase(Pig)
North-West University

Curated by ChEMBL
LigandPNGBDBM50568611(CHEMBL4871075)
Affinity DataIC50: 2.98E+3nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using 1% starch as substrate preincubated for 10 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetPancreatic alpha-amylase(Pig)
North-West University

Curated by ChEMBL
LigandPNGBDBM50568604(CHEMBL4876409)
Affinity DataIC50: 2.98E+3nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using 1% starch as substrate preincubated for 10 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetPancreatic alpha-amylase(Pig)
North-West University

Curated by ChEMBL
LigandPNGBDBM50568603(CHEMBL4869717)
Affinity DataIC50: 2.98E+3nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using 1% starch as substrate preincubated for 10 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetPancreatic alpha-amylase(Pig)
North-West University

Curated by ChEMBL
LigandPNGBDBM50568602(CHEMBL4860734)
Affinity DataIC50: 2.98E+3nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using 1% starch as substrate preincubated for 10 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetPancreatic alpha-amylase(Pig)
North-West University

Curated by ChEMBL
LigandPNGBDBM50568601(CHEMBL4868815)
Affinity DataIC50: 2.98E+3nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using 1% starch as substrate preincubated for 10 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetPancreatic alpha-amylase(Pig)
North-West University

Curated by ChEMBL
LigandPNGBDBM50568600(CHEMBL4875625)
Affinity DataIC50: 2.98E+3nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using 1% starch as substrate preincubated for 10 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetPancreatic alpha-amylase(Pig)
North-West University

Curated by ChEMBL
LigandPNGBDBM50568599(CHEMBL4866987)
Affinity DataIC50: 2.98E+3nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using 1% starch as substrate preincubated for 10 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetPancreatic alpha-amylase(Pig)
North-West University

Curated by ChEMBL
LigandPNGBDBM50568598(CHEMBL4865236)
Affinity DataIC50: 2.98E+3nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using 1% starch as substrate preincubated for 10 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetPancreatic alpha-amylase(Pig)
North-West University

Curated by ChEMBL
LigandPNGBDBM50568597(CHEMBL4846195)
Affinity DataIC50: 2.98E+3nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using 1% starch as substrate preincubated for 10 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetPancreatic alpha-amylase(Pig)
North-West University

Curated by ChEMBL
LigandPNGBDBM50568596(CHEMBL4851123)
Affinity DataIC50: 2.98E+3nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using 1% starch as substrate preincubated for 10 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetPancreatic alpha-amylase(Pig)
North-West University

Curated by ChEMBL
LigandPNGBDBM50568595(CHEMBL4854163)
Affinity DataIC50: 2.98E+3nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using 1% starch as substrate preincubated for 10 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetPancreatic alpha-amylase(Pig)
North-West University

Curated by ChEMBL
LigandPNGBDBM50568594(CHEMBL188521)
Affinity DataIC50: 2.98E+3nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using 1% starch as substrate preincubated for 10 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 3.31E+3nMAssay Description:Inhibition of telomerase in human SGC-7901 cell extract by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetBeta-glucuronidase(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50568584(CHEMBL4865538)
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of beta-glucuronidase (unknown origin) using p-nitrophenyl-beta-D-glucuronide as substrate pre-incubated for 30 mins followed by substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetBeta-glucuronidase(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50008907(D-Saccharic Acid 1,4-Lactone)
Affinity DataIC50: 4.58E+4nMAssay Description:Inhibition of beta-glucuronidase (unknown origin) using p-nitrophenyl-beta-D-glucuronide as substrate pre-incubated for 30 mins followed by substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50568590(CHEMBL4864240)
Affinity DataKi:  128nMAssay Description:Inhibition of recombinant human carbonic anhydrase 1 preincubated with enzyme for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50568589(CHEMBL4868770)
Affinity DataKi:  152nMAssay Description:Inhibition of recombinant human carbonic anhydrase 1 preincubated with enzyme for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  250nMAssay Description:Inhibition of recombinant human carbonic anhydrase 1 preincubated with enzyme for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 1(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50568591(CHEMBL4874430)
Affinity DataKi:  6.43E+3nMAssay Description:Inhibition of recombinant human carbonic anhydrase 1 preincubated with enzyme for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed