21 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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2,4-Disubstituted quinazolines as amyloid-ß aggregation inhibitors with dual cholinesterase inhibition and antioxidant properties: Development and structure-activity relationship (SAR) studies.
University of Waterloo
Structure-Activity Relationship Studies of Isomeric 2,4-Diaminoquinazolines onß-Amyloid Aggregation Kinetics.
University of Waterloo
Amyloid cascade in Alzheimer's disease: Recent advances in medicinal chemistry.
University of Waterloo
A-ring substituted 17ß-arylsulfonamides of 17ß-aminoestra-1,3,5(10)-trien-3-ol as highly potent reversible inhibitors of steroid sulfatase.
University of Waterloo
Investigating the binding interactions of the anti-Alzheimer's drug donepezil with CYP3A4 and P-glycoprotein.
University of Waterloo
Development and evaluation of multifunctional agents for potential treatment of Alzheimer's disease: application to a pyrimidine-2,4-diamine template.
University of Waterloo
A re-examination of the difluoromethylenesulfonic acid group as a phosphotyrosine mimic for PTP1B inhibition.
University of Waterloo
Structure of protein tyrosine phosphatase 1B in complex with inhibitors bearing two phosphotyrosine mimetics.
University of Waterloo
The difluoromethylene group as a replacement for the labile oxygen in steroid sulfates: a new approach to steroid sulfatase inhibitors.
University of Waterloo
Synthesis of an alpha-aminophosphonate nucleoside as an inhibitor of S-adenosyl-L-homocysteine hydrolase.
University of Waterloo
Synthesis of [difluoro-(3-alkenylphenyl)-methyl]-phosphonic acids on non-crosslinked polystyrene and their evaluation as inhibitors of PTP1B.
University of Waterloo
17ß-Arylsulfonamides of 17ß-aminoestra-1,3,5(10)-trien-3-ol as highly potent inhibitors of steroid sulfatase.
University of Waterloo
Inhibition of steroid sulfatase with 4-substituted estrone and estradiol derivatives.
University of Waterloo
Development of 2-substituted-N-(naphth-1-ylmethyl) and N-benzhydrylpyrimidin-4-amines as dual cholinesterase and Aß-aggregation inhibitors: Synthesis and biological evaluation.
University of Waterloo
Design, synthesis and structure-activity relationship (SAR) studies of 2,4-disubstituted pyrimidine derivatives: dual activity as cholinesterase and A β-aggregation inhibitors.
University of Waterloo
Design, synthesis and evaluation of 2,4-disubstituted pyrimidines as cholinesterase inhibitors.
University of Waterloo
Syntheses and kinetic evaluation of hydroxamate-based peptide inhibitors of glyoxalase I.
University of Waterloo
Selective inhibition of human acetylcholinesterase by xanthine derivatives: in vitro inhibition and molecular modeling investigations.
University of Waterloo
Cytochrome P450 binding studies of novel tacrine derivatives: Predicting the risk of hepatotoxicity.
University of Waterloo
Synthesis, antidepressant evaluation and docking studies of long-chain alkylnitroquipazines as serotonin transporter inhibitors.
University of Troms£