Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50038677
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50243184({[2-Bromo-4-(40-bromo-30-sulfamoylbiphenyl-4-ylmet...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50243238(({2-Bromo-4-[40-bromo-30-(difluorosulfamoylmethyl)...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50243239({2-Bromo-4-[40-bromo-30-(difluorosulfamoylmethyl)b...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50243241(PTP1B inhibitor 3 | {3-[(2R)-2-[(2S)-2-[(2S)-2-[(2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50243236([2-Bromo-4-(40-bromo-30-sulfamoylbiphenyl-4-ylmeth...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50243237([2-Bromo-4-(40-bromo-30-sulfamoylbiphenyl-4-ylmeth...)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50075312(difluoro(2-naphthyl)methylphosphonate | difluoro(n...)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50243311((S)-4-((S)-2-((S)-2-((S)-2-amino-3-carboxypropanam...)
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50072598(CHEMBL109646 | difluoro(naphthalen-2-yl)methanesul...)
Affinity DataIC50: 1.75E+5nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50243240(PTP1B inhibitor peptide 1 | (3-((R)-2-((S)-2-((S)-...)
Affinity DataKi:  24nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50243238(({2-Bromo-4-[40-bromo-30-(difluorosulfamoylmethyl)...)
Affinity DataKi:  24nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50243239({2-Bromo-4-[40-bromo-30-(difluorosulfamoylmethyl)b...)
Affinity DataKi:  3.30E+3nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50243237([2-Bromo-4-(40-bromo-30-sulfamoylbiphenyl-4-ylmeth...)
Affinity DataKi:  1.03E+4nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50243236([2-Bromo-4-(40-bromo-30-sulfamoylbiphenyl-4-ylmeth...)
Affinity DataKi:  1.06E+4nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed