23 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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Article Title
Organization
Functionalized N,N-Diphenylamines as Potent and Selective EPAC2 Inhibitors.
University of Texas Medical Branch
Structure-Activity Relationship Studies of Substituted 2-(Isoxazol-3-yl)-2-oxo-N'-phenyl-acetohydrazonoyl Cyanide Analogues: Identification of Potent Exchange Proteins Directly Activated by cAMP (EPAC) Antagonists.
University of Texas Medical Branch
Small molecule inhibitors targeting activator protein 1 (AP-1).
University of Texas Medical Branch
Recent advances in the discovery of small molecules targeting exchange proteins directly activated by cAMP (EPAC).
University of Texas Medical Branch
Identification and characterization of small molecules as potent and specific EPAC2 antagonists.
University of Texas Medical Branch
5-Cyano-6-oxo-1,6-dihydro-pyrimidines as potent antagonists targeting exchange proteins directly activated by cAMP.
University of Texas Medical Branch
Synthesis and screening of 3-substituted thioxanthen-9-one-10,10-dioxides.
University of Texas Medical Branch
Design, synthesis, and pharmacological evaluations of pyrrolo[1,2-a]quinoxaline-based derivatives as potent and selective sirt6 activators.
University of Texas Medical Branch
Scaffold repurposing of fendiline: Identification of potent KRAS plasma membrane localization inhibitors.
University of Texas Medical Branch
Discovery of Potent and Brain-Penetrant GPR52 Agonist that Suppresses Psychostimulant Behavior.
University of Texas Medical Branch
Discovery of phenanthridine analogues as novel chemical probes disrupting the binding of DNA to ΔFosB homodimers and ΔFosB/JunD heterodimers.
University of Texas Medical Branch
Discovery of 4-Phenylpiperidine-2-Carboxamide Analogues as Serotonin 5-HT
University of Texas Medical Branch
Mechanism of Action of an EPAC1-Selective Competitive Partial Agonist.
University of Texas Medical Branch
Synthesis and Pharmacological Evaluation of Noncatechol G Protein Biased and Unbiased Dopamine D1 Receptor Agonists.
University of Texas Medical Branch
Discovery of Orally Bioavailable Chromone Derivatives as Potent and Selective BRD4 Inhibitors: Scaffold Hopping, Optimization, and Pharmacological Evaluation.
University of Texas Medical Branch
Structure-activity relationship studies on Bax activator SMBA1 for the treatment of ER-positive and triple-negative breast cancer.
University of Texas Medical Branch
Synthesis and Biochemical Evaluation of Noncyclic Nucleotide Exchange Proteins Directly Activated by cAMP 1 (EPAC1) Regulators.
University of Texas Medical Branch
Structure-activity relationships of 2-substituted phenyl-N-phenyl-2-oxoacetohydrazonoyl cyanides as novel antagonists of exchange proteins directly activated by cAMP (EPACs).
University of Texas Medical Branch
Exchange proteins directly activated by cAMP (EPACs): Emerging therapeutic targets.
University of Texas Medical Branch
Discovery of potent and selective BRD4 inhibitors capable of blocking TLR3-induced acute airway inflammation.
University of Texas Medical Branch
Drug Discovery Targeting Bromodomain-Containing Protein 4.
University of Texas Medical Branch